Molecular basis for AHFCA recognition by MmfR
The molecular basis of phosphite and hypophosphite recognition by ABC-transporters
... biochemical basis of phosphite and hypophosphite utilisation and the PtxD and HtxA enzymes have been characterised previously 18, 23, 32, 33 , the mechanism of high-affinity ligand binding by the cognate ABC ...
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Molecular basis for bacterial peptidoglycan recognition by LysM domains.
... the basis of our results, we discuss the molecular basis for the promiscuous binding of LysM to polysaccharides including chitin, peptidoglycan and Nod ...
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CiteSeerX — Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
... pri-miRNA recognition by Micro- processor that we present in this study will provide the basis for the future design of an efficient shRNA expres- sion ...
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The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6
... efficacies. Molecular modelling indicates that the majority of non-conserved ligand-interacting residues are at the periphery of the TLR2 binding pocket and in the ligand peptide-interacting regions, which may ...
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The Molecular Basis of Substrate Recognition by the Family of Pellino E3 Ubiquitin Ligases
... 57 determinants enhance Pellino binding affinities as seen with the M. tuberculosis FHA domain- containing FhaA protein, which interacts with its cognate binding partner, MviN, 2-fold stronger than a peptide library ...
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Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition
... the molecular basis for the CsrA/RsmE protein recognition by a specific GGA motif, which is close to the high affinity SELEX-derived consensus sequence (14), it is unclear how other GGA motifs in dif- ...
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Molecular basis of sugar recognition by collectin K1 and the effects of mutations associated with 3MC syndrome
... Results: In this study, we show that CL-K1 primarily targets a subset of high-mannose oligosaccharides present on both self- and non-self structures, and provide the structural basis for its ligand specificity. We ...
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Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome
... carbohydrate recognition, the structures of CL-K1 also reveal the location of residues that are altered in the 3MC syndrome (Ser 169 , Gly 204 and Ser 217 ...
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Molecular basis of class III ligand recognition by PDZ3 in murine protein tyrosine phosphatase PTPN13
... ligand recognition by a PDZ domain now provide a basis for the detailed structural investigation of the promiscuous interaction between the PDZ domains of PTPN13 and of their interaction ...
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Molecular basis for cytolytic T-lymphocyte recognition of the murine cytomegalovirus immediate-early protein pp89.
... By using synthetic peptides, the sequence between residues 161 and 179, which is located within the defined domain, was identified as an epitope presented to BALB/C cytotoxic T lymphocyt[r] ...
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Disease variants of FGFR3 reveal molecular basis for the recognition and new roles for Cdc37 in Hsp90 chaperone system
... Receptor tyrosine kinase FGFR3 is involved in many signaling networks and is frequently mutated in developmental disorders and cancer. The Hsp90/ Cdc37 chaperone system is essential for function of normal and neoplastic ...
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A protein-protein interaction underlies the molecular basis for substrate recognition by an adenosine-to-inosine RNA-editing enzyme
... To gain insight into the molecular mechanisms of ADAR substrate recognition, we compared in vitro and in vivo recognition of dsRNA. We focused on the Caenorhabdi- tis elegans ADARs as worms lacking ...
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Molecular basis of lipid-linked oligosaccharide recognition and processing by bacterial oligosaccharyltransferase Author(s): Publication Date:
... Oligosaccharyltransferase (OST) is a membrane-integral enzyme that catalyzes the transfer of glycans from lipid-linked oligosaccharides (LLOs) onto asparagine side chains, the first step in protein N-glycosylation. We ...
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THE MOLECULAR BASIS OF DOMINANCE
... It is intuitively obvious that there is a relationship between the value of the sensitivity coefficient of the wild type, whose magnitude describes the differential response at[r] ...
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Molecular Basis of Cancer
... The basis for the occurrence of tumors restricted to the retina in patients who inherit one defective allele of RB is not fully understood, but some possible explanations have emerged from the study of mice with ...
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MOLECULAR BASIS OF INHERITANCE
... DNA fingerprinting involves identifying differences in some specific regions in DNA sequence called as repetitive DNA, because in these sequences, a small stretch of DNA is repeated many times. These repetitive DNA are ...
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Molecular basis of alpha-thalassemia
... 4. Clinical description The clinical presentations of α -thalassemia include four widely di- verse conditions from the silent carrier state, the α-thalassemia trait, the clinically variable hemoglobin H (HbH) disease to ...
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Cyclodextrins as the basis of molecular devices
... the molecular level to formulate devices is seen to be the bridge between these ...The molecular recognition of a substrate to its receptor with reactive functions forms a supermolecule that may act ...
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The molecular basis of hypertrophic scars
... and molecular mecha- nisms are different leading to distinct therapeutic out- ...the molecular and cellular mechanism of HTS for technological and scien- tific advances such as the establishment of new ...
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MOLECULAR BASIS FOR GENETIC RECOMBINATION
... The studies of transformed bacteria just mentioned indicate a recombination intermediate in which the molecular segment of donor DNA incorporated into a recipient helix is a[r] ...
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