molecular signatures
Molecular signatures of neutrophil extracellular traps in human visceral leishmaniasis
... that signatures composed by NET-related molecules distinguish asymptomatic individuals from uninfected controls ...these molecular signatures might con- tribute to a better characterization of ...
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Sex-specific lipid molecular signatures in obesity-associated metabolic dysfunctions revealed by lipidomic characterization in ob/ob mouse
... distinctive molecular signatures between sexes using a lipidomics approach to characterize lipid species in liver, perigonadal adipose tissue, and inguinal adipose tissue and correlate them to the ...
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Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice
... the molecular signatures of neurodegeneration similar in the HC and FC and 5) is presenilin-dependent molecular neurodegeneration pro- gressing similarly in FC and ...
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Transcriptomics and Epigenomics in head and neck cancer: available repositories and molecular signatures
... predictive molecular signatures in ...mRNA signatures, 11 and 13 related to miRNA and other non-coding-RNA signatures and 4 analyzing DNA methylation ...identified signatures (36) had a ...
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Bayesian profiling of molecular signatures to predict event times
... profile molecular features on the basis of their prognostic relations to event ...identifying molecular signatures for event times with "small n large p" ...of molecular ...
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The Multiple Molecular Signatures in Gallbladder Carcinoma: from Basic Studies to Clinical Application
... Gallbladder carcinoma (GBC) is a malignant tumor in gastrointestinal system. In this review, we mainly focus on three molecular levels to illuminate the potential molecular mechanisms in gallbladder ...
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Identification of molecular signatures specific for distinct cranial sensory ganglia in the developing chick
... the paucity of markers for the different cell populations. To overcome this restriction we set out to identify mo- lecular signatures for the distinct cranial sensory ganglia at early stages of neuronal ...
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Molecular Signatures in Infrared Spectra of Saliva in Healthy, Chronic and Aggressive Periodontitis
... respective spectrum. Mosquitoes predicted as having a value of < 2.5 were considered to be 1 day of age, 2.5–5.4 as 4 days of age, 5.5–8.4 as 7 days of age, 8.5–11.4 as 10 days of age, 11.5–14.4 as 13 days of age, ...
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Parity related molecular signatures and breast cancer subtypes by estrogen receptor status
... parity-related signatures in genome- wide expression profiling data sets derived from paired tumor-adjacent normal and breast tumor tissues collected from breast cancer ...gene signatures were preserved in ...
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Molecular signatures of mood stabilisers highlight the role of the transcription factor REST/NRSF
... Network analysis of genes significantly modulated in response to mood stabilisers To further explore potential gene networks important in the response to drug challenge, we analysed only[r] ...
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Transcriptomic analysis in pediatric spinal ependymoma reveals distinct molecular signatures
... elucidate molecular mechanisms that give rise to pediatric SEPN, we compared the transcriptomic landscape of SEPNs to that of intracranial ependymomas using genome-wide mRNA and microRNA (miRNA) expression ...
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Diabetes-related molecular signatures in infrared spectra of human saliva
... composite molecular content of saliva then, assuming molecular alterations occur during the disease process, then the chance for IR spectroscopy to distinguish var- ious states of diabetes should be ...
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Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates
... core molecular machinery associated with postnatal granule cell neurogenesis is highly conserved between mice and monkeys and that the timing of this process is delayed relative to birth in mice, as expected given ...
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Leishmania tarentolae molecular signatures in a 300 hundred years old human Brazilian mummy
... Molecular phylogenetic studies confirm the hypothesis that Sauroleishmania species have evolved from the mammalian Leishmania [13]. Therefore, it is not uncon- ceivable to hypothesize that L. tarentolae maintained ...
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Molecular signatures of liver dysfunction are distinct in fungal and bacterial infections in mice
... A transcriptomic approach was used to investigate the molecular hepatic host response to fungal and bacterial infection. Principal component analysis was applied to show general expression trends in the data. The ...
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Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia
... We have previously shown, as have others, that distinct DNA methylation profiles in AML and acute lymphoid leukemia (ALL) are strongly correlated with the presence of specific molecular and cytogenetic subtypes ...
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Ontogeny and phylogeny: molecular signatures of selection, constraint, and temporal pleiotropy in the development of Drosophila
... We tested this prediction by performing pairwise compari- sons of the proportion of genes showing significant evi- dence of positive selection using the comparison between models 7 and 8[r] ...
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Molecular signatures of T cell inhibition in HIV 1 infection
... other molecules exist that instead, regulate and inhibit T- cell activation. Herein, we review the role of inhibitory molecules that are expressed on cells or secreted following HIV-1 infection, and focus on their ...
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Molecular signatures of the evolving immune response in mice following a Bordetella pertussis infection
... of available purified antigens. The inclusion of other antigens, such as outer membrane proteins, would perhaps have allowed a more detailed analysis. Third, in this study we propose murine infection- induced immune ...
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Molecular signatures of chronic myeloid leukemia stem cells
... BCR-ABL tyrosine kinase inhibitors (TKIs) are effective in controlling Philadelphia-positive (Ph + ) chronic myeloid leukemia (CML) are unlikely to cure the disease because TKIs are unable to eradicate leukemia stem ...
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