Molecular Subtypes
Original Article Molecular subtypes of breast cancer with pathological features prevalent in Zhuang and Han ethnic groups in China: a study of 990 patients
... of molecular types and clinical pathological characteristics of breast cancer between Zhuang and Han ethnic groups of patients, and to provide improved treatment regimens for individuals with breast ...four ...
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Calretinin expression in molecular subtypes of invasive carcinoma breast
... Studies have showed that triple negative breast tumors frequently exhibit atypical metastatic patterns, such as early visceral matastases, along with lack of targeted therapy Furthermore, they arise through one of the ...
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Title: Lung-molGPA in EGFR-mutated Adenocarcinoma: Prognostic Implications of Molecular Subtypes and Targeted Therapies
... Figure 1. Kaplan-Meier survival outcome curves in patients with advanced EGFR-muted NSCLC with brain metastases. (a) Overall survival in the study cohort. (b) Overall survival grouped by Lung-molGPA score. (c) Overall ...
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Genomic alterations and molecular subtypes of gastric cancers in Asians
... relevant molecular subtypes of GC with actionable onco- genic ...on molecular mechanisms underlying the pathobiology of GC in relevant disease models, such as patient-derived xenograft (PDX) models ...
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Identifying molecular subtypes related to clinicopathologic factors in pancreatic cancer
... Survival after resection is associated with many clinical factors such as stage, grade (cell differentiation), and metastasis [7,8]. We extracted 20,219 unique genes out of 22,077 genes (from 33,297 of probe ID) for each ...
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hERG1 channel expression associates with molecular subtypes and prognosis in breast cancer
... In the present paper we provide evidence that hERG1 potassium channels are expressed in BC and positively affect patients’ prognosis. Data presented here are the results of a pilot study performed on 40 BC primary ...
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Baseline blood immunological profiling differentiates between Her2– breast cancer molecular subtypes: implications for immunomediated mechanisms of treatment response
... the systemic cytokine expression of two molecular subtypes of breast cancer patients. The patients were grouped according to the ER/PR expression on the primary tumors, ER/PR + , Her2 - patients being ...
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Consensus Molecular Subtypes of Colorectal Cancer and their Clinical Implications
... independent molecular classification systems, based on gene expression data, into a single consensus system with four distinct groups, known as the consensus molecular subtypes (CMS); clinical ...
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DNA methylation epigenotypes in breast cancer molecular subtypes
... the molecular classi- fication of human malignancies and monitoring cancer progression based on a tumor-specific methylation sig- nature ...with molecular subtypes of breast cancer through ...
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Breast cancer molecular subtypes respond differently to preoperative chemotherapy.pdf
... described molecular classes in fine needle aspiration ...the molecular classes of breast tumors in our ...each molecular subtypes corresponded well to the previously described ...
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Molecular subtypes of gastrointestinal stromal tumors and their prognostic and therapeutic implications.
... various molecular subtypes, with differing prognostic and predictive ...genetic subtypes of GIST can guide clinical decision-making both in the adjuvant and the metastatic ...
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Geographic differences in the distribution of molecular subtypes of breast cancer in Brazil
... by molecular markers ...different molecular subtypes, not to mention the opportunity to develop more efficient strategies of prevention and early detection of breast cancer, particu- larly among the ...
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Significance of ERβ expression in different molecular subtypes of breast cancer
... different molecular subtypes of breast cancer was ...four molecular subtypes of breast can- ...three subtypes while the proportion of Her-2 overex- pression type and basal like type was ...
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Original Article Molecular subtypes of male breast cancer by immunohistochemistry
... between molecular subtypes of MBC and clinical behav- iors has rarely well studied [11, ...the molecular subtypes of 98 cases of MBC by immunohistochemistry and examined the correlation with ...
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Contrasting breast cancer molecular subtypes across serial tumor progression stages: biological and prognostic implications
... intrinsic subtypes for clinical management of metastatic breast cancer is not comprehensively ...tumor molecular subtypes during breast cancer ...and molecular subtypes were assigned ...
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Anatomic mapping of molecular subtypes in diffuse glioma
... principal molecular subsets represent distinctive clinical significance and germline ...of molecular pathology in glioma which was published on New England Journal of Medicine ...histological ...
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Differential tumor infiltration by T cells characterizes intrinsic molecular subtypes in breast cancer
... with molecular subtypes has not yet been explored ...the subtypes, originally defined by dissimilar gene expression, exhibit inher- ently differential densities of ...
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Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
... HER2-enriched molecular subtypes did not display distinct methylation ...all molecular subtypes [22,39], and that expression profiles of HER2-positive tumours are very heterogeneous ...
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Role of urokinase plasminogen activator and plasminogen activator inhibitor mRNA expression as prognostic factors in molecular subtypes of breast cancer
... to molecular subtype and were treated according to former treatment ...the molecular subtypes of the patients in their validation cohorts, although this might have had a strong influence on the ...
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Molecular subtypes of urothelial carcinoma are defined by specific gene regulatory systems
... between subtypes, we observed SCCL specific downregulation of ALDH1A2 and overex- pression of CYP26B1, involved in synthesis and degradation of the retinoid RAR ligands, respectively (Additional file 2: Figure ...
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