Monoclonal anti-A/B
A new approach to comparing anti-CD20 antibodies: importance of the lipid rafts in their lytic efficiency
... for B-cell non-Hodgkin’s lymphoma (NHL), representing a major advance in its ...involves anti-CD20 monoclonal Abs (mAbs), which are directed against the CD20-expressing members of the B-cell ...
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B cell targeted therapies
... as B cells, that cause or perpetuate RA. How, then, may B cells be targeted? There are several ways to target B ...promote B cell function and survival, such as IL-6 and B lymphocyte ...
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B cell subpopulations in humans and their differential susceptibility to depletionwith anti CD20 monoclonal antibodies
... on B-cell subpopulations that may be resistant to depletion with anti-CD20 ...of B-cell depletion or repopulation at the time of ...circulating B cells at the time of vaccination [64] or the ...
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Production and analysis of human monoclonal IgG anti-DNA antibodies
... points, B=3, C=1, D=0, ...and B scores are considered to represent active disease in individual systems and a total score of greater than 6 indicates active disease as a ...
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Application of Subtype Specific Monoclonal Antibodies for Rapid Detection and Identification of Influenza A and B Viruses
... and B virus strains: the peroxidase- antiperoxidase (PAP) staining method with two subtype-specific murine monoclonal antibodies, C179 (H1 and H2 specific) and F49 (H3 specific), and an ...
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Ofatumumab: a novel monoclonal anti-CD20 antibody
... profound B-cell depletion lasting 6 to 10 months after end of therapy, and 65% of evaluable patients converted from Bcl-2 positive to Bcl-2 negative peripheral ...
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Endogenous interferon specifically regulates Newcastle disease virus-induced cytokine gene expression in mouse macrophages.
... This hypothesis was further supported by the finding that addition of identical amounts of mouse rIFN-a4 in the presence of monoclonal anti-IFN-,B also exerted a suppressive effect on su[r] ...
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Neutralization of IL-8 decreases tumor PMN-MDSCs and reduces mesenchymalization of claudin-low triple-negative breast cancer
... clinical-stage monoclonal anti–IL-8 antibody, termed HuMax-IL8 (19, 20), was explored both in vitro and in vivo with xenografts of claudin-low breast cancer ...an anti–IL-8 monoclonal antibody ...
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A unique cell surface antigen identifying lymphoid malignancies of B cell origin
... A monoclonal antibody (anti-B1) specific for a unique B cell surface differentiation antigen was used to characterize the malignant cells from patients with leukemias or ...either monoclonal ...
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Control of human B cell tumor growth in severe combined immunodeficiency mice by monoclonal anti B cell antibodies
... of B cells and EBV. In this study, scid mice were infused with B cell lines derived from three patients who developed a B lymphocyte proliferative disorder after bone marrow or organ ...10(6) ...
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Biologic activity and safety of belimumab, a neutralizing anti B lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus
... of anti-dsDNA autoantibod- ies [4]. Therefore, B-cell and plasma cell depletion may be an appropriate therapeutic approach in the treatment of ...SLE. B-lymphocyte stimulator (BLyS) is a member of ...
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Inhibition of IL-13 by Antisense Oligonucleotide Changes Immunoglobulin Isotype Profile in Cultured B-Lymphocytes
... human B-lymphocytes increase the IL-13 m-RNA ...tonsillar B-cells in the presence of anti CD-40 monoclonal antibody as a T- B cell interaction substitute plus IL-4 to promote IL-13 ...
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Establishment of anti mesothelioma monoclonal antibodies
... mouse B cells are generated that produce antibodies against the tumor ...establishing anti-mesothelioma mAbs. We report here the generation of anti-human mesothelioma mAbs for diagnosis and ...
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Proteomic Analysis of Phagocytosis in the Enteric Protozoan Parasite Entamoeba histolytica
... shown). Anti-myc monoclonal antibody 11MO reacted with phagosomes containing red blood cells (B) and beads (data not shown), as well as small vesicles, in the transformant expressing myc-tagged Rab7A ...
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B cell epitopes on infliximab identified by oligopeptide microarray with unprocessed patient sera
... that anti-drug-antibodies (ADA) are induced in a substantial number of patients who are treated with therapeutic monoclonal ...of B and T cell ...
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A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis
... bilized anti-CD3 and anti-CD28 monoclonal antibodies (anti-CD3/anti-CD28; Dynabeads Human T-Activator, Invitrogen, Grand Island, NY, USA); bacterial CpG oli- gonucleotides (CpG); ...
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Minute Virus of Mice NS1 Interacts with the SMN Protein, and They Colocalize in Novel Nuclear Bodies Induced by Parvovirus Infection
... antibody: anti-NS1 polyclonal; secondary antibody: anti-rabbit FITC conjugate) and VP1 (primary antibody: anti-VP1 polyclonal peptide antibody; secondary antibody: anti-mouse TRITC conjugate) ...
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Role of the Metabolic Minor Components in the Regulation of Intermolecular Interaction
... glycoprotein B. The degree of agglutination of the antigens of A (II)-B (IV) blood groups remained stable comparing with the control and amounted ...and B determinants: formation of complexes ...
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Anti T cell immunoglobulin and mucin domain 2 monoclonal antibody exacerbates collagen induced arthritis by stimulating B cells
... immobilized anti-CD3 mAb (5 μ g/ml) in the presence or absence of anti-CD28 mAb (5 μ ...g/ml). B cells were also purified by using the auto-MACS column with B cell isolation ...Purified ...
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Blood Group Discrepancies at a Regional Blood Center
... method. Monoclonal antisera: anti-A, anti-B (Iranian Blood Research and Fractionation, Tehran, Iran) and in-house cells (group A1, B, and O reagent red blood cells) were used for ...
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