Monocyte and Macrophage
Monocyte and macrophage immunometabolism in atherosclerosis
... plaques, macrophage phenotype is shaped largely by external ...inflammatory monocyte/macrophage phenotype either in the bone marrow or in the ...
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Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases
... Figure 2 Human MC and M ϕ differentiation, and distinct subset functions. Human CD14 ++ CD16 - classical MCs leave the bone marrow in a CC-chemokine receptor 2 (CCR2)-dependent manner. In the steady state, classical MCs ...
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Monocyte and Macrophage Apoptosis and Activation During HIV-1 Infection and Antiretroviral Therapy
... and Macrophage Apoptosis and Activation During HIV-1 Infection and Antiretroviral Therapy Abstract Monocytes and macrophages represent a cell lineage integral to multiple aspects of HIV-1 infection, dissemination, ...
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Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease.
... and monocyte-derived macrophages revealed enrichment for genes near IBD loci among those upregulated during macrophage dif- ferentiation or stimulation [ 21 ], suggesting the importance of this cellular ...
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Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation
... the macrophage lineage, are thought to contribute to various pathological changes associated with poor patient ...human monocyte-derived macrophages (Mph) demonstrated greater susceptibility to human ...
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Epigenetic dynamics of monocyte-to-macrophage differentiation
... during monocyte-to-macrophage dif- ferentiation are related to DNA methylation changes around the transcription start sites of the genes, we per- formed a correlation ...
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Innate immunity and monocyte-macrophage activation in atherosclerosis
... in macrophage behaviour and activation within athero- sclerotic ...resident monocyte-macrophages leading to cytokine and chemokine ...biasing macrophage polarisation towards an M1 phenotype, together ...
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Targeting the monocyte-macrophage lineage in solid organ transplantation
... the monocyte–macrophage lineage in transplantation by immunosuppressive ...target monocyte–macrophage lineage cells, multiple categories of currently prescribed immunosuppressive drugs, such ...
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The monocyte-macrophage-mast cell axis in dengue pathogenesis
... Both innate and adaptive immune responses to DENV play significant roles in protection against DENV, but can also elicit pathological responses which may worsen disease [2, 7]. Understanding the mechanisms that regu- ...
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Regulation of HIV 1 transcription in cells of the monocyte macrophage lineage
... the monocyte-macrophage lineage, although replication occurs to a lesser extent than in infected T ...the monocyte-macrophage lineage become differentiated and activated and subsequently ...
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Molecular mechanisms of HIV 1 persistence in the monocyte macrophage lineage
... The protein gp120 produced by monocyte-mac- rophages inhibits TRAIL-mediated cell death by inducing the expression of macrophage-stimulating factor (M- CSF). This envelope protein also up-regulates ...
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Bordetella Adenylate Cyclase Toxin Inhibits Monocyte to Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte like Cells
... IMPORTANCE Macrophages are key sentinel cells of the immune system, and, as such, they are targeted by the toxins produced by the pertussis agent Bordetella per- tussis. The adenylate cyclase toxin (CyaA) mediates immune ...
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Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development
... shape macrophage development Reena ...on monocyte function is less well ...increased monocyte survival and differentiation to macrophages by stimulating CSF-1 ...
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Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in asthma
... Granulocyte macrophage-colony stimulating factor; ICS: Inhaled corticosteroid; IL: Interleukin; LAMP-1: Lysosomal-associated membrane protein 1; MDM: Monocyte-derived macrophages; MFI: Median ...
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Effect of cinnamon water extract on monocyte to macrophage differentiation and scavenger receptor activity
... of monocyte differentiation [17], we measured whether CWE may influence the activity of scavenger receptors in differentiating THP-1 ...primary macrophage culture: Alexa 488 -acLDL uptake was reduced by ...
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Anti myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development
... on monocyte proliferation depended on enzymatic MPO, as we had found this to be the case for the reduction in IL-6 and ...on monocyte/macrophage differentiation, unrelated to ...
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Monocyte/macrophage expression of ABCA1 has minimal contribution to plasma HDL levels
... of monocyte/macrophage ABCA1 to HDL formation in ...donor macrophage ABCA1 or high-fat feeding. Expression of WT macrophage ABCA1 in ABC1 –/– mice resulted in a small but significant increase ...
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Human Cytomegalovirus Stimulates Monocyte-to-Macrophage Differentiation via the Temporal Regulation of Caspase 3
... undergo monocyte-to-macrophage ...known macrophage differentia- tion ...of monocyte-to-macrophage differ- entiation but allows for survival of the HCMV-infected monocyte, while ...
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Monocyte depletion increases local proliferation of macrophage subsets after skeletal muscle injury
... M1 macrophage accumulation Up to now, most studies pointed toward the infiltration of “inflammatory monocytes” to explain the accumulation of tissue macrophages after non-infectious tissue injury like skeletal ...
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Tumor necrosis factor alpha modulates monocyte/macrophage apoprotein E gene expression
... lesions, therefore, we undertook a series of studies to evaluate the effect of TNF alpha on monocyte/macrophage apo E production. The addition of TNF alpha to freshly isolated human monocytes led to a four- ...
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