Monocyte-derived dendritic cells (MDDCs)
DIFFERENTIATION OF MONOCYTE DERIVED DENDRITIC CELLS IN SERUM FREE CONDITIONS
... dendritiform cells of an increased accessory potency showing reduced Mel ...into monocyte derived dendritic cells ...the cells will acquire most of DC criteria; functionally, ...
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SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells
... Monocyte-derived dendritic cells (MDDC) stimulate CD8 ⴙ cytotoxic T lymphocytes (CTL) by presenting endogenous and exog- enous viral peptides via major histocompatibility complex class I ...
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Varying Effects of Different β-Glucans on the Maturation of Porcine Monocyte-Derived Dendritic Cells
... Since dendritic cells (DCs) are the first cells that are encountered after an antigen is taken up by the intestinal epithelial cell barrier, we decided to investigate the effect of two concentrations ...
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Evaluation of Feline Monocyte-Derived Dendritic Cells Loaded with Internally Inactivated Virus as a Vaccine against Feline Immunodeficiency Virus
... Dendritic cells are the only antigen-presenting cells that can present exogenous antigens to both helper and cytolytic T cells and prime Th1-type or Th2-type cellular immune ...functions, ...
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Nsp1α of Porcine Reproductive and Respiratory Syndrome Virus Strain BB0907 Impairs the Function of Monocyte-Derived Dendritic Cells via the Release of Soluble CD83
... of monocyte/macrophage cell development, a reduction in antiviral and inflam- matory cytokines, and an increased secretion of immunosuppressive cytokines ...in monocyte- derived dendritic ...
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Effects of Filovirus Interferon Antagonists on Responses of Human Monocyte-Derived Dendritic Cells to RNA Virus Infection
... responses. MDDCs were transduced with empty, eVP35, mVP40-Ci67 or mVP40- Ravn lentiviruses and subsequently infected with SeV ...control MDDCs, similar to the case with ...
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HIV 2 infects resting CD4+ T cells but not monocyte derived dendritic cells
... the cells in a dose dependent manner (Figure ...in MDDCs was low (Figure ...with MDDCs was 50 times more efficient than that of the wild-type ...
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Quantitative Expression and Virus Transmission Analysis of DC-SIGN on Monocyte-Derived Dendritic Cells
... on MDDCs from the same donor over time as well as between donors ...are derived from projecting the standard curve beyond the last standard and so should not be deemed as ...
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Immunotherapy of Malignant Melanoma with Tumor Lysate Pulsed Autologous Monocyte Derived Dendritic Cells
... In this study, DC vaccination using tumor antigen loaded with mature, monocyte-derived DC led to tumor regression in individual melanoma patients. However, there was a huge discrepancy between the strong ...
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Generation of Mature Monocyte-Derived Dendritic Cells in the Presence of Heparin and Monocyte Conditioned Medium: Phenotypic and Functional Comparison
... It is frequently reported that MCM is required to ensure the development of fully differentiated DC from GM-CSF and IL-4-primed progenitor cell cultures [9], so we examined the expression of CD83 as a unique DC ...
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Infection of human monocyte derived dendritic cells by ANDES Hantavirus enhances pro inflammatory state, the secretion of active MMP 9 and indirectly enhances endothelial permeability
... The presence of high levels of pro-inflammatory cyto- kines both in plasma and lungs have been reported as pathological markers associated with HCPS in humans. These excesses of pro-inflammatory cytokines are secreted in ...
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Alteration of T cell immunity by lentiviral transduction of human monocyte derived dendritic cells
... the cells were resuspended and fixed in 1% paraformaldehyde in PBS and analyzed using a FACSCalibur flow cytometer and the CELLQUEST program (Becton ...live cells were gated by forward- and side-light ...
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Foal Monocyte-Derived Dendritic Cells Become Activated upon Rhodococcus equi Infection
... horse cells revealed a statistically significant difference in MHC class II expression between infected and noninfected mMOs and ...noninfected cells at the same time ...
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Severe Acute Respiratory Syndrome Coronavirus Fails To Activate Cytokine-Mediated Innate Immune Responses in Cultured Human Monocyte-Derived Dendritic Cells
... Activation of host innate immune responses was studied in severe acute respiratory syndrome coronavirus (SCV)-infected human A549 lung epithelial cells, macrophages, and dendritic cells (DCs). In all ...
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Antitumor Efficacy of Human Monocyte-Derived Dendritic Cells: Comparing Effects of two Monocyte Isolation Methods
... Cell surface staining was performed using monoclonal antibodies fluorescently labeled with fluorescein isothio- cyanate (FITC), allophycocyanin (APC) or phycoerythrin (PE). Anti-CD3 and anti-CD14 antibodies (Immuno- ...
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S100A9 protein is a novel ligand for the CD85j receptor and its interaction is implicated in the control of HIV 1 replication by NK cells
... to dendritic cells, NK cells and T lym- phocytes ...tumor cells, has been suggested to be an escape mechanism of gamma delta T-cell antitumoral activity [13] or continuous ligation of CD85j on ...
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Comparative analysis of miRNA profile in human dendritic cells infected with respiratory syncytial virus and human metapneumovirus
... To further understand the differential activation of DCs by RSV and HMPV, we investigated herein whether these viruses induce distinct profiles of microRNAs (miRNAs), a kind of small non-coding RNA molecules of 19-24 ...
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Complementary Antiviral Efficacy of Hydroxyurea and Protease Inhibitors in Human Immunodeficiency Virus-Infected Dendritic Cells and Lymphocytes
... Dendritic cells are susceptible to human immunodeficiency virus (HIV) infection and may transmit the virus to T cells in ...in dendritic cells because preclinical testing of ...
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High Secretion of Interferons by Human Plasmacytoid Dendritic Cells upon Recognition of Middle East Respiratory Syndrome Coronavirus
... immune cells such as antigen-presenting cells ...B cells, macrophages, monocyte-derived/myeloid den- dritic cells (MDDCs/mDCs), and by plasmacytoid dendritic ...
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HIV-1 Envelope Glycan Moieties Modulate HIV-1 Transmission
... to monocyte-derived macro- phages (MDMs), (iii) bound monocyte-derived dendritic cells (MoDCs), and (iv) trans-infected primary lymphocytes via ...TZMbl cells, MDMs, ...
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