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Morphometry data from mdx and C57 mice

Modifying function and fibrosis of cardiac and skeletal muscle from mdx mice

Modifying function and fibrosis of cardiac and skeletal muscle from mdx mice

... Importantly, these functional parameters improved to values that were not significantly different to values measured in C57 mice. While treatment with pirfenidone has reproducibly shown antifibrotic effects ...

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Long-term administration of pirfenidone improves cardiac function in mdx mice

Long-term administration of pirfenidone improves cardiac function in mdx mice

... the mdx mouse undergoes an acute inflammatory response early in life with increased expression of cytokines including TNF-α and TGF-β, which may lay the foundation for pathways leading to increased ...15-month-old ...

31

Modifying function and fibrosis of cardiac and skeletal muscle from mdx mice

Modifying function and fibrosis of cardiac and skeletal muscle from mdx mice

... resulting from continual cycles of degeneration of the muscle tissues followed by inadequate regeneration of the muscles, is progressive in both cardiac and skeletal dystrophic ...the mdx mouse which ...

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Analyses of the differentiation potential of satellite cells from myoD
 / , mdx, and PMP22 C22 mice

Analyses of the differentiation potential of satellite cells from myoD / , mdx, and PMP22 C22 mice

... grown from single cells, we again found no ultimate difference in differentiation effi- ciency (data not ...of mdx results by differ- ences in the experimental design or genetic background of the ...

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Effect of Passive Transfer of Spleen Cells from Immunized Mice with Hydatid Cyst Antigens on the Growth of Melanoma Cancer in C57/Black Mice

Effect of Passive Transfer of Spleen Cells from Immunized Mice with Hydatid Cyst Antigens on the Growth of Melanoma Cancer in C57/Black Mice

... This work was carried out in collaboration between all authors. Author STR contributed in designing the study, performed the experimental work and wrote the first draft of the manuscript. Author SMS contributed in ...

6

The chondrogenic response to exercise in the proximal femur of normal and mdx mice

The chondrogenic response to exercise in the proximal femur of normal and mdx mice

... the mdx mice, although not enlarged, are also not significantly reduced in size relative to sedentary controls (Table ...Our data suggests that chondrogenic activity in both the sedentary and ...

6

SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice

SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice

... phin-deficient mdx mice and normal control C57Bl/10 (BL10) mice were purchased from The Jackson Labora- tory (Bar Harbor, ...12-m-old mdx mice in a single bolus through the tail ...

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Alterations in cardiac dihydropyridine receptors and calcium channel function in MDX mice

Alterations in cardiac dihydropyridine receptors and calcium channel function in MDX mice

... biopsies from human failing hearts and plasma samples showing low content of noradrenalin in tissue and high levels of circulating ...these data could also be interpreted in the opposite manner concluding ...

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CiteSeerX — Stimulation of calcineurin signaling attenuates the dystrophic pathology in mdx mice

CiteSeerX — Stimulation of calcineurin signaling attenuates the dystrophic pathology in mdx mice

... that mice expressing enhanced muscle calcineurin activity (CnA*) displayed elevated levels of utrophin around their ...CnA* mice with mdx mice to determine the suitability of elevating ...

10

Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice

Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice

... cells from the mdx mouse — an animal model for DMD that possesses a premature stop codon in the dystrophin ...of mdx myotubes to gentamicin led to the expression and localization of dystrophin to the ...

8

miR-146a deficiency does not aggravate muscular dystrophy in mdx mice

miR-146a deficiency does not aggravate muscular dystrophy in mdx mice

... generated from fibro- adipogenic progenitors (FAPs), produce high levels of proteins like collagens and fibronectin in response to el- evated transforming growth factor- β (TGF- β ) expression [21, ...

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Treatment with rGDF11 does not improve the dystrophic muscle pathology of mdx mice

Treatment with rGDF11 does not improve the dystrophic muscle pathology of mdx mice

... of myofiber size and numbers, sections were stained for laminin. Muscle sections were fixed in 4 % PFA for 30 min, washed three times with PBS, blocked with 5 % BSA in PBS for 1 h at room temperature (RT), and then ...

8

Advanced MDX - Performance, Optimization and the MDX Script

Advanced MDX - Performance, Optimization and the MDX Script

... in MDX Scripting Cache Warming Strategies Creating a Second Hierarchy to Choose the Adding Values Not Directly in Source Situations that Prevent Block Computation Type of Date Data Monitoring for Block ...

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Disease-modifying bioactivity of intravenous cardiosphere-derived cells and exosomes in mdx mice

Disease-modifying bioactivity of intravenous cardiosphere-derived cells and exosomes in mdx mice

... of mdx mice when delivered intravenously — a clinically innocuous ...reports, data presented here support the idea that CDCs work by secreting EXOs to antag- onize multiple pathological processes ...

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Long-term quercetin dietary enrichment decreases muscle injury in mdx mice

Long-term quercetin dietary enrichment decreases muscle injury in mdx mice

... diaphragms from mdx-control (A) and mdx-quercetin (B) treated ...between mdx-control and mdx-quercetin treatments (C). Data are means ± ...muscle from typical disease pro- ...

9

Muscle reorganisation through local injection of stem cells in the diaphragm of mdx mice

Muscle reorganisation through local injection of stem cells in the diaphragm of mdx mice

... 9 mice, including 3 control BALB/Cmice, 3 5-month-old mdx mice without stem cell injections and 3 mdx mice injected with stem cells, were ...cells from GFP-labelled rabbit ...

7

Placental histomorphology and morphometry in the pregnant mice treated with cell phone radiation

Placental histomorphology and morphometry in the pregnant mice treated with cell phone radiation

... 57 aims to investigate the probable histo- morphological and morphometrical alterations of the placenta after exposure to EMFs. For this purpose, the cell phone radiation period was extended to day 17 of gestation. ...

10

Silica nanoparticles induce reversible damage of spermatogenic cells via RIPK1 signal pathways in C57 mice

Silica nanoparticles induce reversible damage of spermatogenic cells via RIPK1 signal pathways in C57 mice

... These data suggested that SiNPs could induce apoptosis and necroptosis in the spermatogenic cells by activating the RIPK1 pathway resulting from oxidative stress in male ...

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Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice

Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice

... These data suggest that SC cell differentiation and fate choice are directly dependent on sig- nals derived by MFs and IL-10 plays a crucial role in mediating the SCs-MFs ...Our data are based on a new ...

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Combined effect of AMPK/PPAR agonists and exercise training in mdx mice functional performance

Combined effect of AMPK/PPAR agonists and exercise training in mdx mice functional performance

... Interestingly, the exercise training group presented increased values of training intensity in wheel activity when compared to the animals that also received exercise mimetics - the time of activity per day was similar ...

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