Motility and invasion
A unique protein phosphatase with kelch like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion
... Our functional studies have shown that the only point of essentiality for PPKL in the malaria parasite is ookinete differentiation, particularly in the latter stages when the machinery for motility and ...
15
Urotensin II receptor determines prognosis of bladder cancer regulating cell motility/invasion
... cell motility and invasion, respectively, in T24 cells if compared to untreated ...both motility and invasion of human bladder cancer ...
10
The role of the tissue microenvironment in the regulation of cancer cell motility and invasion
... The structural and mechanical properties of extracellu- lar matrix and the presence of signaling molecules from embedded cells have a profound influence on cancer cell motility, tissue invasion, ...
8
S100P enhances the motility and invasion of human trophoblast cell lines
... both motility and invasion in these lines since its specific down-regulation using targeted siRNA technology is sufficient to abrogate these ...in motility and ...characterised motility and ...
18
By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization
... cell motility, invasion and metastasis have yet to be ...cell motility and invasion via the induction of matrix metalloproteinase-7 ...chondrosarcoma invasion and ...
20
Surface attachment, promoted by the actomyosin system of Toxoplasma gondii is important for efficient gliding motility and invasion
... in motility and invasion [24] or to an un- usually stable actin (encoded by a single copy gene [47]), which persists many days and parasite generations after gene excision and can polymerize via an unusual ...
23
Abnormal Smooth Muscle Contraction Alters Gut Motility and Propagates Epithelial invasion in the Larval Zebrafish Intestine
... GI motility, with and without phospho-MLC, highlighting CaD's ability to independently modulate contractile ...epithelial invasion was observed pointing to the unique role for force propagation in ...
151
mMaspin: The Mouse Homolog of a Human Tumor Suppressor Gene Inhibits Mammary Tumor Invasion and Motility
... These data have demonstrated that mMaspin functions to inhibit mouse mammary tumor cell invasion and motility, just as human maspin in- hibits human mammary carcinoma cells, sug- gesting[r] ...
11
Regulation of breast cancer cell motility by T cell lymphoma invasion and metastasis inducing protein
... Not all studies support a role for Tiam1 as an onco- gene. Thus, in renal cell carcinoma [38], breast carci- noma [39], and gastric cancer [40], an inverse correlation has also been observed between Tiam1 expression and ...
15
Knockdown of WAVE3 impairs HGF induced migration and invasion of prostate cancer cells
... In summary, it is safe to conclude that WAVE-3 plays an important role during cellular motility and invasion in pros- tate cancer cells. It is also actively involved in the mediation of HGF induced changes ...
10
Reciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls invasive phenotypes in glioblastoma
... Here we demonstrate an important mechanism whereby the Abl interacting adaptor proteins Abi1 and Crk differentially impinge on Abl to regulate invasive GBM. Using several cell lines as a model of classical GBM, a type ...
16
Alterations in integrin expression modulates invasion of pancreatic cancer cells
... increased motility and invasion through matrigel and fibronectin, and reduced adhesion to matrigel and ...the invasion or adhesion of Clone #8 cells to lam- inin, but loss of α6 significantly reduced ...
12
Invading, Leading and Navigating Cells in Caenorhabditis elegans: Insights into Cell Movement in Vivo
... AC invasion and the expression of genes associated with later aspects of AC differentiation (Matus et ...ing invasion effectors such as matrix metalloproteinases ...cell motility and invasion ...
26
<p>CSNK2A1 Promotes Gastric Cancer Invasion Through the PI3K-Akt-mTOR Signaling Pathway</p>
... Several indicator molecules were found to regulate GC cell invasion and metastasis via the EMT signaling pathway. 26–28 CSNK2A1 was overexpressed in colorectal cancer and modulated cell proliferation and ...
9
Docetaxel resistance in prostate cancer: evaluating associated phenotypic changes and potential for resistance transfer via exosomes
... While docetaxel remains as the current gold standard for HRPC treatment, it only increases overall survival by on average 2.5 months and those patients who initially respond eventually develop resistance to this drug. In ...
12
Original Article MiR-22 functions as a biomarker and regulates cell proliferation, cycle, apoptosis, migration and invasion in renal cell carcinoma
... cell motility, migration and invasion, as well as induced cell cycle arrest and promoted apoptosis in RCC cells, while blockage of miR- 22 reversed these effects in RCC ...
13
Swiprosin-1 stimulates cancer invasion and metastasis by increasing the Rho family of GTPase signaling
... SM3). Invasion of B16F1 cells ectopically expressing myc-tagged Swiprosin-1 was enhanced to a similar extent as that of B16F10 cells (Figure 5F and Supplementary movie ...
12
RNAi silencing of c-Myc inhibits cell migration, invasion, and proliferation in HepG2 human hepatocellular carcinoma cell line: c-Myc silencing in hepatocellular carcinoma cell
... In summary, inhibition of endogenous c-Myc using siRNA technology could reduce the motility, invasion, and proliferation of HCC cells. Although we obtained comparable c-Myc inhibition with plasmid ...
6
Oxazepine Derivative as an Antitumor Agent and Snail1 Inhibitor against Human Colorectal Adenocarcinoma
... the invasion suppressor gene CDH1, thereby leading to the transcriptional suppression of crucial transmembrane adhesion glycoprotein E-cadherin ...to invasion, motility, increased apoptotic ...
7
Galangin, a novel dietary flavonoid, attenuates metastatic feature via PKC/ERK signaling pathway in TPA-treated liver cancer HepG2 cells
... Tumour invasion and migration are the primary causes of morbidity in patients with ...the invasion ability and motility of cancer cells, we used a transwell chamber invasion and migration ...
11