Motor deficits
Regularizing firing patterns of rat subthalamic neurons ameliorates parkinsonian motor deficits
... The subthalamic nucleus (STN), the only excitatory structure in the basal ganglia, holds a key position in the basal ganglia circuitry and is an optimal clinical target for deep brain stimulation (DBS) (1, 2) for ...
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CONGENITAL RUBELLA: PATHOGENESIS OF MOTOR DEFICITS
... loss and a history of maternal rubella revealed a relation between the character and degree of their motor deficits and the maternal gestational age at which the infection had occurred..[r] ...
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Addition of Capsaicin to Local Anesthetics for Spinal Anesthesia in Rats Shortens Motor Deficits and Prolongs Anti Nociception
... than motor or autonomic deficits, is often clinically desirable but traditional local anesthetics rarely have such selective ...over motor block in rat sciatic ...capsaicin. Motor block was ...
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Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice
... neurological deficits over 15 months, suggesting a milder form of the disease in mice ...strong motor deficits as early as 6 months of age, including reduction of spontaneous movement, bizarre limb ...
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Deranged NMDAergic cortico subthalamic transmission underlies parkinsonian motor deficits
... pathway, we first locally delivered the specific NMDA receptor antagonists D-(–)-2-amino-5-phosphonopentanoic acid (AP5) and cis-4-[phosphomethyl]-piperidine-2-carboxylic acid (CGS) and the ...
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Assessing motor deficits in compressive neuropathy using quantitative electromyography
... Sensory, motor, and combined nerve conduction studies were used to stratify individuals by severity of CTS such that we had one experimental group with evidence of motor involvement (severe CTS), one group ...
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Atypical lateralization of motor circuit functional connectivity in children with autism is associated with motor deficits
... fine motor control have been suggested to be more focal preventing conduction delays and enabling rapid processing [33, 34], whereas visuospatial functions require more interhemispheric integration to represent ...
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SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington’s disease
... The striatum, the brain region that degenerates most significantly in HD (11), plays an important role in controlling voluntary behavior and motor skill acquisition (12). Medium spiny neurons (MSNs) are the ...
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Gross Motor Deficits in Children Prenatally Exposed to Alcohol: A Meta-analysis
... gross motor tasks based on several standardized assessments; GMTOT, Gross Motor Total Score; M-ABC, Movement Assessment Battery for Children; M-ABC2, Movement Assessment Battery for Children, Second ...
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White Matter Changes Contribute to Corpus Callosum Atrophy in the Elderly: The LADIS Study
... Therefore, CC atrophy in this population may be an indicator for reduced neocortical functional integrity, which may be associated with some of the cognitive and motor deficits observed [r] ...
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The psychophysiological effects of Tai chi and exercise in residential Schizophrenic patients: a 3 arm randomized controlled trial
... Background: Patients with schizophrenia are characterized by high prevalence rates and chronicity that often leads to long-term institutionalization. Under the traditional medical model, treatment usually emphasizes the ...
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Motor and cognitive deficits in aged tau knockout mice in two background strains
... We interrogated the cognitive function of 12-month old tau -/- mice using the Y-maze test. Consistent with our previous observation [5], tau ablation in the Bl6/ 129sv background caused a significantly decreased time ...
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Motor Intervention and Assessment Instruments in Autism Spectrum Disorders
... Therefore, motor intervention programs have been increasingly used for the development of children with ASD, both at the motor level and at the social lev- ...el. Motor deficits are a hallmark ...
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Functional neuroimaging of traumatic brain injury: advances and clinical utility
... TBI and attempted to characterize the relationship between structural damage (DAI) and metabolic status in the ante- rior and posterior corpus callosum. These authors acquired MRS, fMRI, and DTI volumes from a total of ...
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Neuroprotective Effects of Tetramethylpyrazine against Dopaminergic Neuron Injury in a Rat Model of Parkinson's Disease Induced by MPTP
... Parkinson's disease (PD) is the second most prevalent progressive neurodegenerative disease. Although several hypotheses have been proposed to explain the pathogenesis of PD, apoptotic cell death and oxidative stress are ...
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Clinical motion analyses over eight consecutive years in a child with crouch gait: a case report
... the motor deficits associated with spastic CP (that is, muscle weakness, shortened muscle- tendon lengths, spasticity, and impaired selective motor control) to crouch ...
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Cognitive-motor integration deficits in young adult athletes following concussion
... rule-based motor performance (“cognitive-motor integration”) in adults affected by age-related mild brain dysfunction ...required motor output to the guiding visual information ...gross motor ...
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White Matter Microstructural Abnormality in Children with Hydrocephalus Detected by Probabilistic Diffusion Tractography
... patients with hydrocephalus are in such domains as motor, visuospatial, and other nonverbal intelligences.1-3 These deficits have been associated with myelin sheath breakdown, axonal deg[r] ...
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Clinical diagnosis and management in early Huntington's disease: a review
... for motor, cognitive, and psychiatric alterations, which are the three major symptom domains of this devastating progressive ...limited, motor and psychiatric symptoms often respond to pharmacotherapy, and ...
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Practice Parameter: Diagnostic assessment of the child with cerebral palsyReport of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society
... Since the advent of neuroimaging, it has become more apparent that children with CP may have con- genital brain malformations. Data from this same group of 1,426 children found that 7% of patients who had a CT scan and ...
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