motor neuron disease
Study on treatment method of motor neuron disease based on Jiweiling injection
... Motor neuron disease is a chronic progressive neurodegenerative disease with unknown etiology of selective spinal cord anterior horn cells, the group of brain stem motor neurons, cortex ...
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Identification and outcomes of clinical phenotypes in amyotrophic lateral sclerosis/motor neuron disease: Australian National Motor Neuron Disease observational cohort
... Consecutive patients in whom the treating neurologist felt had a likely diagnosis of ALS/MND were invited to participate in the national registry. ALS/MND care deliv- ery in Australia is through 10 major clinics and the ...
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Cervicothoracic Intradural Arachnoid Cyst Misdiagnosed as Motor Neuron Disease
... of motor neuron disease in adults and usually causes death within a few years ...lower motor neuron signs in the bulbar, arm and leg musculature with clear evidence of ...
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Establishing the UK DNA Bank for motor neuron disease (MND)
... Motor Neuron Disease (MND) is a fatal, rapidly pro- gressive disease that affects the brain and spinal cord and which ultimately leads to respiratory failure around 2 – 5 years following ...
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Imaging muscle as a potential biomarker of denervation in motor neuron disease
... the disease stage of our patients, it is likely that both fluid compartment shifts and sarcolemmal fat replacement related to denervation (evidenced by associations with lower MUNIX) are responsible for the ...
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Vitamin E deficiency and risk of equine motor neuron disease
... in motor neuron death but not necessarily the sole etiologic agent/ ...the disease, we are an in a position to test spe- cific hypotheses regarding the etiologic factor(s) while taking into ...
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Marchiafava-Bignami disease mimics motor neuron disease: case report
... lower motor neuron signs, the initial diagnosis was motor neuron ...primary motor cortices ...mimic motor neuron disease ...
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Frontostriatal deficit in Motor Neuron Disease/Amyotrophic Lateral Sclerosis (MND/ALS)
... reported: Motor Neuron Disease/Amyotrophic Lateral Sclerosis/Dementia Syndrome (MND/ALS/DS) and Motor Neuron Disease/Amyotrophic Lateral Sclerosis/ Aphasia Syndrome (MND/ALS/AS) ...
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Turkish families with juvenile motor neuron disease broaden the phenotypic spectrum of SPG11
... limb-onset disease at the ages of 14 (male) and 16 (female), with walking difficulties, twitching, spasticity, and fasciculation in ...lower motor neuron (UMN and LMN) involvement was ...progressive ...
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Cellular therapy in motor neuron disease: A case report
... Motor Neuron Disease (MND) is a progressive neurodegenerative ...of motor neurons in the spinal cord and motor cortex; selectively sparing the sensory neurons in this ...
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MR Spectroscopy Findings in Early Stages of Motor Neuron Disease
... the motor cortex is useful to detect upper motor neuron ...the motor cortex compared with ...modifies disease progression at later ...
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Evaluation of function, disability and participation of patients with motor neuron disease
... Aims: To objective the symptoms and estimate the necessity of technical or social aid as well as to receive parameters for treatment, this evaluation was carried out. The aim is the preparation of core sets for patients ...
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The Why of Sporadic Motor Neuron Disease - Many Factors, still a Mystery?
... is not adequately inactivated and is increasing oxidative and nitrosative stress. This is likewise supposed to be a mechanism in a specific familial form of the disease with mutation and malfunction of ...
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Dominantly Inherited Amyotrophic Lateral Sclerosis (Motor Neuron Disease)
... The term amyotrophic lateral sclerosis (ALS) was first introduced by Charcot to describe cases with mixed upper and lower motor neuron signs without.. This is paper #46 f[r] ...
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Longitudinal multi-modal muscle-based biomarker assessment in motor neuron disease
... Results MND patients exhibited 18% higher whole-body mean muscle relative T2-signal than controls (95% CI 7–29%, p < 0.01), maximal in leg muscles (left tibialis anterior 71% (95% CI 33–122%, p < 0.01). Clinical ...
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Heavy metals in locus ceruleus and motor neurons in motor neuron disease
... LC neuron was defined as any neuron (pigmented or non-pigmented) with a maximum diameter greater than 26 μm (the length of the side of one grid square) that contained 10 or more AMG ...spinal motor ...
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Evaluating a novel cervical orthosis, the Sheffield Support Snood, in patients with amyotrophic lateral sclerosis/motor neuron disease with neck weakness
... Severe weakness of the neck extensor muscles has been described in various neuromuscular disorders including myasthenia gravis, spinal muscular atrophy and amyotrophic lateral sclerosis (ALS) / motor neurone ...
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Evaluation of the role of an antioxidant gene in NSC-34 motor neuron-like cells as a model of a motor neuron disease
... While SMA has traditionally been classified as a pure lower MN disease, it is becoming clear that supplementary cells and tissue types are particularly susceptible to decreased SMN expression. Current ther- ...
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Process evaluation and exploration of telehealth in motor neuron disease in a UK specialist centre
... the disease and the holistic aims of care in this terminal disease mean telehealth systems will need to differ from more simplistic, target-driven care systems (such as blood pressure ...
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Post polio Syndrome: More Than Just a Lower Motor Neuron Disease
... aerobic regimens must be carefully tailored to individual fitness levels (147). While some studies show improved endurance following mid- to high-intensity aerobic exercises (139, 140), a recent study (148) highlights ...
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