mouse epiblast stem cells
Medaka Cleavage Embryos Are Capable of Generating ES-Like Cell Cultures
... tipotent stem cell cultures from earlier developing embryos has not been ...pluripotent stem (iPS) cells have been ob- tained by forced expression of pluripotency tran- scription factors even in ...
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Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors
... gastrulation, epiblast cells are pluripotent and their fate is thought to be constrained principally by their ...of epiblast stem cells (EpiSCs), self-renewing pluripotent cell lines ...
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Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells
... the epiblast- maintenance condition and under the NPC condition for 1 (NP1) and 2 (NP2) days using ...the epiblast and specific domains of the neural plate ...in mouse embryos from ...the ...
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Epiblast derived stem cells in embryonic and adult tissues
... germ cells from other pluripotent cells of the early ...germ cells and by ES cells, but is weakly expressed by the epiblast and other surrounding embry- onic cells (Ginsburg et ...
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Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification
... the epiblast during gastrulation (Pereira et ...streak epiblast and Nanog protein levels actually increased in epiblast cells as they moved towards the ...the epiblast had no apparent ...
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The absence of Prep1 causes p53 dependent apoptosis of mouse pluripotent epiblast cells
... protein, die mostly at E17.5 with liver hypoplasia, anemia, angiogenesis and eye defects (Ferretti et al., 2006). The hematopoietic phenotype is due to malfunction of long-term repopulating hematopoietic stem ...
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The principles that govern transcription factor network functions in stem cells
... stage epiblast of blastocyst stage embryos (Boroviak et ...whereas mouse EpiSCs are in the primed pluripotent state that mimics the character of the late post-implantation stage epiblast (Brons et ...
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Self renewing epiblast stem cells exhibit continual delineation of germ cells with epigenetic reprogramming in vitro
... from epiblast cells from which PGCs originate in ...– Mouse Genome Informatics) is detected in Blimp1-positive cells at the end of the PGC specification process (Hayashi et ...germ ...
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Spermatogenesis from epiblast and primordial germ cells following transplantation into postnatal mouse testis
... germ cells from day 0-3 mouse pups did not show spermatogenic colonies after transplantation into adult testes (McLean et ...however, epiblast cells at ...Sertoli cells lack tight ...
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Targeted DamID reveals differential binding of mammalian pluripotency factors
... homogeneous cells and antisera with high ...fewer cells than ChIP-based ...in mouse embryonic stem cells, epiblast-like cells and primordial germ cell-like cells ...
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Conversion from mouse embryonic to extra embryonic endoderm stem cells reveals distinct differentiation capacities of pluripotent stem cell states
... the mouse pre-implantation blastocyst comprises epiblast progenitor and primitive endoderm cells of which cognate embryonic (mESCs) or extra-embryonic (XEN) stem cell lines can be ...each ...
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The pluripotent state in mouse and human
... the mouse counterparts (see ...the mouse post-implantation epiblast (Brons et ...These cells, called epiblast stem cells or EpiSCs, although pluripotent by the criteria of ...
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Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state
... ES cells from different strains of mice tested, including 129, CBA and NOD (Nichols et ...of mouse somatic cells to induced pluripotency is also enhanced using 2i-LIF (Silva et ...pluripotent ...
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Dynamics of Wnt activity on the acquisition of ectoderm potency in epiblast stem cells
... anterior epiblast during ...the mouse, the impact of the loss of Dkk1 function is manifested as a complete truncation of the head (Mukhopadhyay et ...of cells from the anterior epiblast of the ...
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Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning
... progenitor cells in the mammalian embryo communicate with each other and their extra-embryonic ...in stem cells. Self-renewing embryonic stem (ES) cell lines can be derived from the inner cell ...
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Multipotency of mouse trophoblast stem cells
... of cells; the inner cytotropho- blast cells and the outer syncytiotrophoblast cells that differentiate from the ...of stem cells [49–54]. TSCs are a heterogeneous population of ...
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Differential plasticity of epiblast and primitive endoderm precursors within the ICM of the early mouse embryo
... ICM cells does not correlate with mutually exclusive expression of Nanog and ...ICM cells as well as the majority of trophoblast cells, and Gata4 was not ...the epiblast and PrE layers. In ...
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Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrPC signaling
... arachnoid-pia stem cells (APSCs) from adult human ...neuroglia-like cells migrated from the spheres and show a unique morphology (phase ...+ cells was observed with markers of OCT4 or SOX2 in ...
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Mouse induced pluripotent stem cells
... of mouse iPS cells by Takahashi and Yamanaka in 2006, research in this area has advanced at an astonishing ...reprogramme mouse cells has been successfully extended to human cells, ...
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Long noncoding RNA CCDC144NL-AS1 knockdown induces naïve-like state conversion of human pluripotent stem cells
... To obtain candidate lncRNAs tightly correlated with hu- man pluripotency, we took 32 pluripotency-associated genes as a module (PGM) (Additional file 4: Figure S1e) and calculated the membership values for all noncoding ...
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