Mouse neural progenitor cells
CCL11 promotes migration and proliferation of mouse neural progenitor cells
... immune cells, endothelial cells, fibroblasts, and brain cells after ischemic ...immune cells traffick- ing during inflammatory ...for neural progenitor cell guidance and orienta- ...
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Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells
... the neural differentiation efficiency for each cell line, we quantified the expression levels of several pluripotency (OCT4, SOX2), mesodermal (Brachyury), endodermal (GATA4), and dorsal NPC (Nestin, PAX6, SOX1, ...
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Exosomes released from neural progenitor cells and induced neural progenitor cells regulate neurogenesis through miR-21a
... in mouse stroke models [9, ...primary neural stem/progenitor cells (NPCs)-derived exosomes (EXOs) could promote the proliferation of NPCs in vitro, implying that iNPCs have the potential to ...
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Lymphotoxin β receptor-mediated NFκB signaling promotes glial lineage differentiation and inhibits neuronal lineage differentiation in mouse brain neural stem/progenitor cells
... using mouse stainless steel brain ...dissociated cells were cultured at a density of 2 × 10 5 cells/ml in DMEM/F12 NSC/NPC proliferation medium containing × 1 B27 Supplement, 20 ng/ml epidermal ...
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Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development
... neuronal progenitor marker Tbr2 (red, bottom) and with Hoechst ...+ cells in the cortex, calculated per unit ventricle length, using images similar to ...
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Humanized neuronal chimeric mouse brain generated by neonatally engrafted human iPSC-derived primitive neural progenitor cells
... complex neural network formation of the human ...of neural cells in the mouse brain, the majority of the pNPCs generate neurons, particularly in the gray ...of neural circuits in the ...
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Original Article Inhibitory effects of murine cytomegalovirus infection on neural stem/progenitor cells of embryonic mouse brains
... nerve cells by suppressing expression of key upstream and downstream genes of Wnt signal path- ...its neural invasion process, in which the promoter of this gene plays a key role ...
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Mathematical modeling supports substantial mouse neural progenitor cell death
... A primary objection to the idea of substantial NPC death is the intuition that ≥ 50% NPC death throughout neu- rodevelopment would preclude expansion of the NPC pool. However, the level of NPC death need not be con- ...
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Production of Neural Progenitors from Bone Marrow Mesenchymal Stem Cells
... have neural progenitors for differentiation to specific neuron ...stem cells (MSCs) are easily isolated, cultured, manipulated ex vivo, showing great potential for thera- peutic ...studied neural ...
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Cyclosporine Inhibits Mouse Cytomegalovirus Infection via a Cyclophilin-Dependent Pathway Specifically in Neural Stem/Progenitor Cells
... Inhibition of MCMV replication independent of cal- cineurin-mediated immunosuppressive activity but dependent on CyP inhibition. Cs and FK506 have a common target, cal- cineurin, that mediates immunosuppression in T ...
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Selective expression of presenilin 1 in neural progenitor cells rescues the cerebral hemorrhages and cortical lamination defects in presenilin 1 null mutant mice
... We have also generated transgenic mice expressing Cre recombinase under the control of the nestin intron 2 enhancer/tk promoter (NesCrenls mice). Cre expression in these lines has been verified by both western blotting ...
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Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos
... of neural crest progenitors. Sox10-GFP-positive cells are produced transiently from mouse embryonic stem (ES) cells by treatment with retinoic acid in combination with Fgf8b and the cytokine ...
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Direct conversion of mouse astrocytes into neural progenitor cells and specific lineages of neurons
... sertoli cells, and urine ...somatic cells into iNPCs suggests a common iNPCs re- programming ...for mouse fibro- blast reprogramming, can superimpose a NPC fate onto astrocytes ...the neural ...
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Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington’s disease patient cells
... a neural-induction medium consisting of neurobasal medium (Invitrogen) supplemented with 2% B27 (Invitrogen), 1% glutamine, and 40 ng/ml of ...neurons, neural progenitor cells were ...
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Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration
... knockout mouse line to delete XBP1 in retinal neural progenitor cells by crossing an XBP1 floxed line [14] with the Chx10-Cre line, in which a Cre-recombinase- GFP fusion protein is expressed ...
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Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression
... stem cells and precursor cells within the adult ...in cells of the embryonic brain versus the adult ...stem cells and the subsequent production of IPs (Harris et ...stem cells undergo ...
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ADAM23 promotes neuronal differentiation of human neural progenitor cells
... III-tubulin-positive cells in the slices was quantified by counting the intersection of fibers with a grid of cycloids (cycloid length: 30 μ m) according to a previously described stereological analytical method ...
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Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133 tumor initiating cells
... Cancer cells are characterized by rapid uptake of glucose. Unlike normal cells, that require growth factor signaling to utilize available resources for every cellular processes, cancer cells display ...
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Molecular basis for Flk1 expression in hemato cardiovascular progenitors in the mouse
... 5B, upper panel). The binding specificity was confirmed by competition experiments using an excess amount of control oligonucleotides, as described previously (Lien et al., 1999), including one with a mutated sequence. ...
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Lentivirus Gene Transfer in Murine Hematopoietic Progenitor Cells Is Compromised by a Delay in Proviral Integration and Results in Transduction Mosaicism and Heterogeneous Gene Expression in Progeny Cells
... Lentivirus vector constructs. Lentivirus vectors were generated by transient transfection in 293T cells using the three-plasmid system as previously described (31). The packaging plasmid pCMV R8.91 provides the ...
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