Mouse peritoneal macrophages
Stimulation of cholesteryl ester synthesis in mouse peritoneal macrophages by cholesterol rich very low density lipoproteins from the Watanabe heritable hyperlipidemic rabbit, an animal model of familial hypercholesterolemia
... with mouse peritoneal macrophages, the VLDL from WHHL rabbit (WHHL- VLDL) stimulated cholesteryl [14C]oleate synthesis 124-fold more than did VLDL from the normal Japanese White rabbit ...
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Foam cell forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity
... J774 macrophages, unlike mouse peritoneal macrophages, accumulate large amounts of CE from unmodified low density lipoprotein ...and mouse peritoneal ...two macrophages, ...
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Cholesteryl ester accumulation in mouse peritoneal macrophages induced by β migrating very low density lipoproteins from patients with atypical dysbetalipoproteinemia
... The d < 1.006 lipoproteins of patients in a kindred with atypical dysbetalipoproteinemia induced marked cholesteryl ester accumulation in mouse peritoneal macrophages. The affected family members ...
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Stimulated arachidonate metabolism during foam cell transformation of mouse peritoneal macrophages with oxidized low density lipoprotein
... in mouse peritoneal macrophages incubated with various types of ...by macrophages and stimulated macrophage prostaglandin E2 (PGE2) and leukotriene C4 syntheses, respectively, ...
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Phosphatidylserine-Mediated Phagocytosis of Influenza A Virus-Infected Cells by Mouse Peritoneal Macrophages
... by mouse peritoneal ...with mouse peritoneal ...of macrophages, but control mock-infected cells were not significantly engulfed by macrophages (data not ...by macrophages ...
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Inactivation of lysosomal proteases by oxidized low density lipoprotein is partially responsible for its poor degradation by mouse peritoneal macrophages
... When mouse peritoneal macrophages (MPM) were preincubated for 21 h at 37 degrees C with ox-LDL, LDL, or vortex-aggregated LDL, only ox-LDL inhibited the subsequent degradation of 125I-labeled forms ...
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Hypertriglyceridemic Very Low Density Lipoproteins Induce Triglyceride Synthesis and Accumulation in Mouse Peritoneal Macrophages
... Triglyceride-rich lipoproteins may be responsible for the lipid accumulation in macrophages that can occur in hypertriglyceridemia. Chylomicrons and very low density lipoproteins (VLDL, total and with flotation ...
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Thromboxane synthase is preferentially conserved in activated mouse peritoneal macrophages
... lipoxygenase metabolites relative to resident cells. Since some products have been shown to modulate immune functions, we examined how the AA metabolic enzyme activities regulate the products that are synthesized. We ...
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Thrombospondin binds to monocytes macrophages and mediates platelet monocyte adhesion
... Thrombospondin (TSP) is a multifunctional platelet glycoprotein synthesized by a variety of cells in culture including monocytes and macrophages. We now report that 125I-TSP binds specifically, saturably, and ...
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IL-17 induces macrophages to M2-like phenotype via NF-κB
... in mouse peritoneal macrophages treated with ...il-17-treated macrophages transfected with ...in mouse peritoneal macrophages by real-time ...
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Anti inflammatory activities of Aedes aegypti cecropins and their protection against murine endotoxin shock
... (LPS)-stimulated mouse peritoneal macrophages and human peripheral blood mononuclear cells (PBMCs) with low toxicity to mammalian ...a mouse model of endotoxin shock, AeaeCec1-5 effectively ...
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Original Article Luteolin regulates CLP-induced sepsis mice by inhibiting PPAR-γ/STAT/MyD88 pathway
... on mouse peritoneal macrophage was tested by MTT ...of macrophages, downregu- lated the expression of MyD88 and TLR4 in mouse peritoneal macrophages, regulated the expression of ...
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Original Article Mcl-1 signals pathway inhibitors in mouse peritoneal macrophage apoptosis infected with the Xinjiang strain of M. tuberculosis
... XJ-MTB-infected mouse peritoneal macrophages (Figure 3), which confirmed that the MAPK signalling pathway is the major sig- nalling pathway involved in regulating the expression of Mcl-1 in XJ-MTB ...
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Differences in iNOS and arginase expression and activity in the macrophages of rats are responsible for the resistance against T gondii infection
... non-activated peritoneal macrophages isolated from 5 strains of rat (Sprague-Dawley (SD), Lewis, Wistar, F344 and Brown Norway (BN)) and 4 strains of mouse (Swiss, BALB/c, C57BL/6 and ...in ...
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EVALUATION OF IN VITRO IMMUNOMODULATORY EFFECTS OF SOYABEAN (GLYCINE MAX L) EXTRACTS ON MOUSE IMMUNE SYSTEM
... into hypochlorous acid (HOCl), a potent bactericidal agent. HOCl is an important component of host defense mechanism against invading pathogens. 37 On exposure of different concentrations (800-6.25µg/ml) of SBE and SBM ...
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MD-2 is required for disulfide HMGB1-dependent TLR4 signaling
... primary macrophages, isolated from human blood, were stimulated with HMGB1 (1 µg/ml) or other stimuli (Poly I:C, S100A12, LPS, PGN, and CpG DNA) in vitro, plus increasing amounts of P5779 (or scrambled control ...
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BMP4 is increased in the aortas of diabetic ApoE knockout mice and enhances uptake of oxidized low density lipoprotein into peritoneal macrophages
... in mouse aortas and in human coronary arter- ies, suggesting that BMPs, including BMP4, are in- volved in the formation of atherosclerosis ...in macrophages in atherosclerotic ...into macrophages in ...
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Therapeutic Effect of Scrophularia striata Ethanolic Extract against Localized Cutaneous Leishmaniasis Caused by Leishmania major (MRHO/IR/75/ER)
... 15% FBS. Cells were plated in 8-chamber Lab- Tek tissue-culture slides, and adherent macro- phages were infected with late logarithmic pro- mastigote parasites at the parasites-to macro- phage ratio of 5:1. After 2 h of ...
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Poly(ADP-Ribosyl)ation of High Mobility Group Box 1 (HMGB1) Protein Enhances Inhibition of Efferocytosis
... compared with HMGB1-treated macrophages. (D.1) Phagocytosis assays were performed after preincubation of macrophages for 2 h with 1 μ g/mL PARylated HMGB1 or free PAR and compared with control BSA-treated ...
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A targeted DNA vaccine encoding Fas ligand defines its dual role in the regulation of experimental autoimmune encephalomyelitis
... activated macrophages, thioglycollate-elicited peritoneal macro- phages were activated (in vitro) by LPS, with or without the addition of either control IgG from naive Lewis rats or with purified ...
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