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MPO-ANCA

Comparative investigation of respiratory tract involvement in granulomatosis with polyangiitis between PR3-ANCA positive and MPO-ANCA positive cases: a retrospective cohort study

Comparative investigation of respiratory tract involvement in granulomatosis with polyangiitis between PR3-ANCA positive and MPO-ANCA positive cases: a retrospective cohort study

... of MPO-ANCA positive patients was ...whereas MPO-ANCA was as- sociated with HLA-DQ ...with MPO-ANCA associated vasculitis or healthy ...

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MPO-ANCA associated crescentic glomerulonephritis with numerous immune complexes: case report

MPO-ANCA associated crescentic glomerulonephritis with numerous immune complexes: case report

... Laboratory data are shown in Table 1. Serum creatinine was markedly increased (i.e., 8.3 mg/dL). A urinalysis showed massive proteinuria (i.e., 3+), and the sediment contained 50 to 100 red blood cells/high power field ...

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Interstitial Pneumonia in a 94 Year Old Woman with MPO ANCA Positive Vasculitis

Interstitial Pneumonia in a 94 Year Old Woman with MPO ANCA Positive Vasculitis

... by MPO-ANCA asso- ciated ...by MPO-ANCA associated vasculitis was over 60 years, with a male ...by MPO-ANCA associated vasculitis in the ...

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Alpha-1 Antitrypsin Deficiency Presenting with MPO-ANCA Associated Vasculitis and Aortic Dissection

Alpha-1 Antitrypsin Deficiency Presenting with MPO-ANCA Associated Vasculitis and Aortic Dissection

... CT angiography demonstrated a type B aortic dissection, extending from the left subclavian artery to the right superior femoral artery (Figures 1(a) and 1(c)). Visceral perfusion and renal perfusion were adequate. The ...

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Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome

Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome

... We concluded that the patient had double-positive Goodpasture ’ s syndrome with falsely negative immuno- fluorescence due to a not perfectly preserved frozen biopsy specimen. Induction therapy was established with plasma ...

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Successful non-surgical treatment on bilateral spontaneous perirenal giant hematomas in rapidly progressive glomerulonephritis with MPO-ANCA positive

Successful non-surgical treatment on bilateral spontaneous perirenal giant hematomas in rapidly progressive glomerulonephritis with MPO-ANCA positive

... In this case, we concluded that her experiencing pro- gressive deterioration in renal function was caused by rapidly progressive glomerulonephritis (RPGN) because of the following reasons. There was a finding of ...

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MPO-ANCA associated vasculitis with mononeuritis multiplex following influenza vaccination

MPO-ANCA associated vasculitis with mononeuritis multiplex following influenza vaccination

... In this report, we described a patient with MPO-ANCA vasculitis with renal involvement and mononeuritis mul- tiplex two weeks after seasonal influenza vaccination. Since the patient showed overlapping sets ...

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Rituximab in relapsing and de novo MPO ANCA-associated vasculitis with severe renal involvement: a case series

Rituximab in relapsing and de novo MPO ANCA-associated vasculitis with severe renal involvement: a case series

... the ANCA type, not just based on clinical features, for the characterisation of the ...recurrent MPO-ANCA associated vasculitis and severe renal involvement treated with RTX with no CYC ...

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Anti-neutrophil extracellular trap antibody in a patient with relapse of anti-neutrophil cytoplasmic antibody-associated vasculitis: a case report

Anti-neutrophil extracellular trap antibody in a patient with relapse of anti-neutrophil cytoplasmic antibody-associated vasculitis: a case report

... After another 6 months of observation, the serum Cr and MPO-ANCA levels were re-elevated (Cr, 2.0 mg/dl; MPO-ANCA, 195 IU/ml) and proteinuria and micro- scopic hematuria were re-appeared. The ...

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Index Catalog // Carolina Digital Repository

Index Catalog // Carolina Digital Repository

... vasculitis. ANCA have been found to be markers of disease since 1985 and more recently have been found to be pathogenic in vivo 5 ...with ANCA disease have a polyclonal response to ANCA autoantigens ...

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Anti Neutrophil Cytoplasmic Antibodies Stimulate Release of Neutrophil Microparticles

Anti Neutrophil Cytoplasmic Antibodies Stimulate Release of Neutrophil Microparticles

... or MPO-ANCA derived from patients with AAV or with healthy control polyclonal IgG at a concentration of 200 ...PR3-ANCA, MPO-ANCA, and control IgG had no effect on NMP release from ...

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Automated interpretation of ANCA patterns   a new approach in the serology of ANCA associated vasculitis

Automated interpretation of ANCA patterns a new approach in the serology of ANCA associated vasculitis

... 70 ANCA positive samples with distinct ANCA specificities (anti-MPO-ANCA, n = 20 and anti-PR3-ANCA, n = 50) and 100 healthy con- trols was used for the development and refinement of ...

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Epitope analysis of anti myeloperoxidase antibodies in propylthiouracil induced antineutrophil cytoplasmic antibody associated vasculitis

Epitope analysis of anti myeloperoxidase antibodies in propylthiouracil induced antineutrophil cytoplasmic antibody associated vasculitis

... of ANCA, in particular, MPO-ANCA, in the development of ...AAV. ANCA can mediate the activation of primed neutrophils, resulting in a respiratory burst and degranu- lation, which could play a ...

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Clinico-pathological considerations in a 48-years-old female with acute kidney injury: is it lupus nephritis, ANCA-associated vasculitis or something else?

Clinico-pathological considerations in a 48-years-old female with acute kidney injury: is it lupus nephritis, ANCA-associated vasculitis or something else?

... of MPO, PR3 and lactoferrine ANCAs with a strong posi- tivity for MPO and lactoferrine ANCAs and a low posi- tivity for PR3 ...ANCAs. ANCA detection using multiplex technology also detected ...

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Original Article Laser microdissection-based analysis of cytokine balance in the kidneys of patients with ANCA-associated glomerulonephritis

Original Article Laser microdissection-based analysis of cytokine balance in the kidneys of patients with ANCA-associated glomerulonephritis

... to MPO (MPO-ANCA) is predominant in MPA patients and Churg- Strauss syndrome (CSS) patients ...with ANCA-associatedGN (AAGN) compared to th- ose with non-proliferative forms of GN and Ig ...

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Prognosis of pulmonary fibrosis presenting with a usual interstitial pneumonia pattern on computed tomography in patients with myeloperoxidase anti-neutrophil cytoplasmic antibody-related nephritis: a retrospective single-center study

Prognosis of pulmonary fibrosis presenting with a usual interstitial pneumonia pattern on computed tomography in patients with myeloperoxidase anti-neutrophil cytoplasmic antibody-related nephritis: a retrospective single-center study

... with MPO-ANCA nephritis who visited the De- partment of Nephrology in Fujita Health University Hos- pital from 2008 to ...serum ANCA positivity from among the patients with ...(in ...

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ANCA-Associated Vasculitis: Advancement in
Pathogenesis, Clinical Features and Management

ANCA-Associated Vasculitis: Advancement in Pathogenesis, Clinical Features and Management

... for ANCA screening and then confirm positive results by enzyme-linked immunosorbent assay (ELISA) to differentiate proteinase 3 (PR3)-ANCA or c-ANCA from myeloperoxidase (MPO)-ANCA or ...

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nrrheum.2017.140.pdf

nrrheum.2017.140.pdf

... for ANCA by indirect immunofluorescence (IIF) and to test for proteinase 3 (PR3)-ANCAs and myeloperoxidase (MPO)-ANCAs in IIF-positive samples; the ideal approach was to perform IIF and immunoassay on all ...

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Predictors of outcome in idiopathic rapidly progressive glomerulonephritis (IRPGN)

Predictors of outcome in idiopathic rapidly progressive glomerulonephritis (IRPGN)

... between ANCA (+) and ANCA (-) ...in ANCA (-) ...in ANCA (+) patients in our study may reflect an increased susceptibility of these patients to treatment and this could explain in part the ...

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Complement-targeted therapy: development of C5- and C5a-targeted inhibition

Complement-targeted therapy: development of C5- and C5a-targeted inhibition

... causing ANCA-associated vasculitis (AAV) in ...by ANCA cause the release of substances that activate the alternative pathway of complement activation ...with MPO-ANCA almost entirely inhibited ...

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