mRNA, messenger
Twist of messenger Fate: novel mechanisms for TDP43 in modulating mRNA decay and alternative polyadenylation
... The PAS selection is regulated by multiple mechanisms, acting in combination (reviewed in Shi, 2012). According to the survival of the fittest model (Figure 1.12a), the alternative polyadenylation outcome depends on the ...
91
Up-regulation of brain-derived neurotrophic factor in the dorsal root ganglion of the rat bone cancer pain model
... BDNF mRNA (messenger ribonucleic acid) and protein were significantly increased in L3 dorsal root ganglia after intra-tibial inoculation of MRMT-1 rat breast cancer ...BDNF mRNA, exon 1–9 variant ...
9
Killing the messenger: new insights into nonsense mediated mRNA decay
... the mRNA can be targeted for destruction? For a long time it has been argued that the cell really has only a single system capable of sensing in- frame stop codons — ...abnormal mRNA species must occur in ...
5
Polyethylene glycol–poly(ε-benzyloxycarbonyl-L-lysine)-conjugated VEGF siRNA for antiangiogenic gene therapy in hepatocellular carcinoma
... Notes: Tumor-bearing mice were killed 28 days after initial injection, then tumor tissues were collected and processed for paraffin-embedded sections and immunohistochemical staining (n=5). Brown staining in the tissue ...
13
Original Article Correlation between CT characteristics and P16 expression in malignant meningioma
... P16 messenger ribonucleic acid (mRNA) in car- cinoma tissues and para-carcinoma tissues was detected via reverse transcription-polymerase chain reaction (RT- PCR), and the level of P16 protein was detected ...
7
Unavailability of liver triacylglycerol increases serum cholesterol concentration induced by dietary cholesterol in exogenously hypercholesterolemic (ExHC) rats
... hepatic messenger RNA (mRNA) abundance related to lipid metabolism—acetyl- coenzyme A [CoA] acyltransferase (Acat1), apolipoprotein B (Apob), apolipoprotein E (Apoe), fatty acid translocase (Cd36), CPT on ...
11
Isolation and Characterization of Adenovirus Messenger Ribonucleic Acid in Productive Infection
... Isolation and Characterization of Adenovirus Messenger Ribonucleic Acid in Productive lInfection Messenger ribonucleic acid mRNA from cells productively infected with adenovirus type 2 w[r] ...
11
rco-3, a Gene Involved in Glucose Transport and Conidiation in Neurospora crassa
... The messenger RNA (mRNA) levels of conidiation-specific genes in this strain were elevated during development in submerged culture (-1 et al. Here we report the cloning [r] ...
10
Estrogen-mediated hemangioma-derived stem cells through estrogen receptor-α for infantile hemangioma
... A quantitative real-time RT-PCR assay was used to quantify VEGF-A and FGF-2 messenger RNA (mRNA). Media containing E2 were washed out, and all cells were serum starved for 24 h before harvesting RNA from ...
8
Modulation of proinsulin messenger RNA after partial pancreatectomy in rats Relationships to glucose homeostasis
... Proinsulin mRNA was measured by dot hybridization to complementary ...proinsulin mRNA. After 90% Px a marked increase of proinsulin mRNA occurred, but it was insufficient and it was not maintained ...
10
Possible Cis-acting signal that could be involved in the localization of different mRNAs in neuronal axons
... The mRNAs containing the U-rich region could be com- plexed with a protein responsible for transport toward the axon, just as HuD complexes with and stabilizes the tau messenger [9]. HuD itself has the capacity to ...
10
Virus-specific Ribonucleic Acid Synthesis in KB Cells Infected with Herpes Simplex Virus
... This paper describes studies of the relationship of virus messenger ribonucleic acid mRNA synthesis to virus DNA, antigenic protein, and infectious-particle production in KB cells infect[r] ...
8
Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy Interaction between hemodynamic and thyroid hormone induced signals
... beta-MHC mRNA followed by the appearance of comparable levels of the beta-MHC protein in parallel to an increase in the left ventricular ...the mRNA and protein levels, despite progression of left ...
9
Molecular basis for the deficiency of complement 1 inhibitor in type I hereditary angioneurotic edema
... INH messenger RNA (mRNA) by Northern blot analysis indicated that in HANE patients' monocytes a message of normal size is present at about half the concentration of that from normal ...
6
Differential Expression of Bacteriophage Genomes in Vegetative and Sporulating Cells of Bacillus subtilis
... Deoxyribonucleic acid-ribonucleic acid hybrid analysis of relative amounts of phage-specific and host-specific messenger ribonucleic acid mRNA present in infected cells suggested that 33[r] ...
13
Discordant Reports of miRNA Expression in Cervical Cancer: An Upshot of Overlapping Factors
... cervical cancer [11] amongst others. MicroRNAs (miRNA) act by inhibiting messenger RNA (mRNA) in several biological processes, including proliferation, differentiation, development, metabolism and cell ...
9
Chemical stability of bacteriophage T7 early mRNA.
... At 20 min after T7 infection 12 min after rifampin addition, at which time total T7 early mRNA has lost messenger activity, individual mRNA species still remain as large size RNAs Fig.. [r] ...
5
SMaRT: A novel approach to gene therapy
... Most messenger RNA precursors (pre-mRNA) undergo cis-splicing in which introns are excised and the adjoining exons from a single pre-mRNA are ligated together to form mature ...
5
Circulating thyrotropin receptor messenger ribonucleic acid is not an effective marker in the follow-up of differentiated thyroid carcinoma
... TSHR mRNA seems to be highly sensitive in TgAb-positive patients ...TSHR mRNA assay in TgAb-positive patients, 24 out of 27 were positive for either TSHR mRNA or TgAb with sensitivity ...TSHR ...
5
Defects in DNA and globin messenger RNA in homozygotes for hemoglobin Lepore
... Lepore mRNA are similar to the amounts of alpha- and Lepore globin synthesized in intact cells and by isolated mRNA in a cell-free ...Lepore-globin mRNA can completely hybridize to full- length or ...
8