Multiple drug resistance
Prevalence and Multiple Drug Resistance of Shigella sonnei Isolated from Diarrheal Stool of Children
... As a conclusion, antibiotic therapy using ciprofloxacin has shown advantages in the treatment of shigellosis, when reaching high concentration in serum and feces. In conclusion, this study revealed that there is a ...
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Multiple Drug Resistance: A Fast-Growing Threat
... antibiotic resistance can be solved. Resistance mechanisms are pandemic and has created enormous clinical and financial burden on health care systems ...judgment. Multiple drug ...
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Multiple drug resistance and biocide resistance in Escherichia coli environmental isolates from hospital and household settings
... exhibited resistance to Trimethoprim-sulfamethoxazole (Fig. 1). Resistance to amoxicillin was seen in ...the resistance was seen in only 19% of the isolates. Resistance to cephalosporins ...
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Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates
... Multiple drug resistance is a condition enabling a disease causing organism to resist distinct drugs or chemicals of a wide variety of structure and function targeted at eradicating the ...multidrug ...
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Troglitazone reverses the multiple drug resistance phenotype in cancer cells
... drug resistance. We previously demonstrated doxorubicin (DOX) resistance in K562 human leukemia cells that was associated with upregulation of glyoxalase 1 (GLO-1) and histone H3 ...the ...
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Mutations in the yeast PDR3, PDR4, PDR7 and PDR9 pleiotropic (multiple) drug resistance loci affect the transcript level of an ATP binding cassette transporter encoding gene, PDR5.
... The yeast pleiotropic (multiple drug) resistance gene PDR5 encodes a product with homology to a large number of membrane transport proteins including the mammalian multiple [r] ...
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Significance of MDR1 and multiple drug resistance in refractory human epileptic brain
... defined multiple drug resistance involve drug- efflux transporters such as the ATP-binding cassette sub- family B member 1 (ABCB1), also known as MDR1 or P- glycoprotein (P-gp) ...with ...
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Overcoming multiple drug resistance mechanisms in medulloblastoma
... Lomustine and TMZ are oral DNA alkylating cytotoxic drugs used for the treatment of primary and recurrent MB, respectively. The activity of both drugs depends on the absence of direct repair by O6-methylguanine-DNA-meth- ...
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NANOMEDICINE: will it offer possibilities to overcome multiple drug resistance in cancer?
... This review is written with the purpose to review the current nanomedicine literature and provide an outlook on the developments in utilizing nanoscale drug constructs in treatment of solid cancers as well as in ...
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High Prevalence of Multiple Drug Resistance among ESBLs-Producing Klebsiella pneumoniae Isolated from Hospitalized Patients in Isfahan, Iran
... Klebsiella pneumoniae is an important opportunistic nosocomial pathogen causing a variety of infections including urinary tract infections, pneumonia, septicemia, wound infections and infections in the intensive care ...
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Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat?
... ated resistance mutations in nematode communities of cattle, sheep, bison and horses provides a powerful new tool that enables unparalleled sensitivity of detection and permits screening for the emergence of ...
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Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces.
... While transformants containing the high copy number autonomously replicating plasmid were resistant to both cycloheximide and sulfometuron methyl, inte- grative transforma[r] ...
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Identification and characterization of class 1 integrons among atypical enteropathogenic Escherichia coli isolated from children under 5 years of age.
... of multiple drug resistance of EPEC strains in this study demonstrated the presence of integrons carrying antimicrobial resistance gene ...of drug resistant ...antibiotic ...
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Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms
... example, drug may be prevented from entering the cells or be pumped out of the cells; it may become enzymatically inactive, mutation or alteration in expression of the drug target, and derangement in ...
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Role of micro-RNAs in drug resistance of multiple myeloma
... in drug resistance of MM ...melphalan resistance even in the presence of BMSCs ...modulated drug influx-efflux transporters SLC7A5/LAT1 and the ABC transporter ABCC1/MRP1, further supporting ...
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ANTIMICROBIAL ACTIVITY OF STEM BARK OF COMBRETUM ALBIDUM G DON; A TRADITIONAL MEDICINAL LIANA
... years, drug resistance to human pathogenic bacteria has been commonly reported from all over the ...of multiple drug resistance to human pathogenic organisms, this has necessitated a ...
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Incidence of multidrug resistant Vibrio parahaemolyticus isolated from Ponnani, South India.
... antibiotic resistance index are comparable with those observed for Vibrios from coastal and brackish water areas of Kerala ...with drug resistant groups of ...the drug resistance of ...the ...
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Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?
... BTK may promote B-cell migration via activation of the CXCR4-CXCL12 (SDF-1) axis [67]. CXCL12 is a pleiotropic chemo-attractant for CXCR4-expressing cells, including HSCs and MMSCs, and retains these cells in the BM. ...
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MULTI DRUG RESISTANT PATTERNS OF BIOFILM FORMING AEROMONAS HYDROPHILA FROM URINE SAMPLES
... enhanced resistance to antibiotics and clearance by the host immune system, the resistance of enteropathogenic bacteria to commonly prescribed antibiotics is increasing both in developing as well as in ...
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Diffusely Adherent E. coli Burden in Low Socio-Economic Pediatric Population
... In conclusion, our findings support the significant association of DAEC with diarrheal diseases in children of non breast feeding age group. This study revealed that DAEC is less predominant pathotype but strongly ...
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