Muscle degeneration
Quantitative MRI comparison of multifidus muscle degeneration in thoracolumbar fractures treated with open and minimally invasive approach
... of muscle degeneration, the ac- tual true amount of degeneration, visible as fatty degener- ation, has not been evaluated ...detectable muscle degeneration and fatty ...of muscle ...
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Association between back muscle degeneration and spinal pelvic parameters in patients with degenerative spinal kyphosis
... of muscle size (CSA) and a increase of fatty infiltration (FI) are considered to be two indications of muscle degeneration [14, ...paraspinal muscle composition and morphology in patients with ...
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Interplay of IKK/NF κB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy
... and muscle necrosis and in skeletal muscle fibers to limit regeneration through the inhibition of muscle progenitor ...and muscle function in mdx ...
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Protective role of Moringa oleifera leaf-based diet on protein- energy malnutrition induced skeletal muscle degeneration
... of muscle degeneration on calcium homeostasis in disease conditions, it would therefore be of great advantage to develop natural compounds that counteract the negative ...
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Nuclear entrapment and extracellular depletion of PCOLCE is associated with muscle degeneration in oculopharyngeal muscular dystrophy
... skeletal muscle tissue maintains cellular function and fibre structure, and further provides an en- vironment for muscle fibre ...skeletal muscle myopathy and muscle fibrosis [2]. Fi- brotic ...
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Ceasing of muscle function with aging: is it the consequence of intrinsic muscle degeneration or a secondary effect of neuronal impairments?
... tibial muscle (35–44 months) were determined [29], a reduction of and abnormalities within the myofibrils were the main causes of atrophy at the cellular ...of muscle fibres and alterations in the ...
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Oleuropein aglycone peracetylated (3,4-DHPEA-EA(P)) attenuates H 2O -mediated cytotoxicity in C2C12 myocytes via inactivation of p-JNK/p-c-Jun signaling pathway
... As previously mentioned, an accumulation of oxidative damage could contribute to the loss of muscular homeostasis, function and atrophy. Interestingly, we have shown that the increase of oxidative stress is associated ...
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Metabolic remodeling agents show beneficial effects in the dystrophin- deficient mdx mouse model
... improve muscle function and overall activity in dystrophic ...improve muscle function in 5 weeks old MDX ...soleus muscle, an increase of mRNA expression of PGC-1α, cyt c and a trend for PDK-4 sug- ...
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The cytolinker Pigs is a direct target and a negative regulator of Notch signalling
... Gas2-like proteins harbour putative binding sites for both the actin and the microtubule cytoskeleton and could thus mediate crosstalk between these cytoskeletal systems. Family members are highly conserved in all ...
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Duchenne muscular dystrophy (DMD) detail study
... of muscle weakness in this condition is the mutated gene dystrophin (muscular protein) which progressively leads to muscle ...as muscle weakness and progressively ends up in a stage where the person ...
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Gamma-Sarcoglycan Mediated Mechanotransduction in Skeletal Muscle
... severe muscle degeneration and signaling defects in response to mechanical load without causing susceptibility to contractile ...the muscle-specific protein archvillin as a g-SG and dystrophic ...
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Programmed cell death specifically eliminates one part of a locust pleuroaxillary muscle after the imaginal moult
... the degeneration of M114c. Both treatments inhibited the degeneration of ...and muscle degeneration must be independent ...the degeneration of M114, but still allowed ...the ...
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Correlation between intervertebral disc degeneration, paraspinal muscle atrophy, and lumbar facet joints degeneration in patients with lumbar disc herniation
... fidus muscle degeneration and chronic low back pain, degenerative disc disease, radiculopathy, and scoliosis has been proposed [7 – ...9]. Muscle atrophy and fatty infil- tration to the multifidus ...
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Attempting to Compensate for Reduced Neuronal Nitric Oxide Synthase Protein with Nitrate Supplementation Cannot Overcome Metabolic Dysfunction but Rather Has Detrimental Effects in Dystrophin-Deficient mdx Muscle
... supplementation reduces skeletal muscle degeneration and enhances mitochondrial function in< i> 1015. mdx</i> mice[r] ...
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Interleukin-15 facilitates muscle regeneration through modulation of fibro/adipogenic progenitors
... the muscle regeneration by regulating ...skeletal muscle, which is one of critical myokines ...in muscle [37], which can increase insulin sensitivity and promote lipid oxidation [38, ...in ...
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ARTHROGRYPOSIS
... showed a mild muscle fiber atrophy character-.. ized by patchy myofibrillar degeneration and.[r] ...
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Optimising antisense oligonucleotide-mediated exon skipping for Duchenne muscular dystrophy
... To optimise delivery and effi ciency, different administration routes have been compared. Intravenous injection resulted rapidly in high plasma levels, which were quickly cleared. Peak plasma levels were twofold lower ...
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Towards defining muscular regions of interest from axial magnetic resonance imaging with anatomical cross reference: part II cervical spine musculature
... suboccipital muscle has a long axis close to perpendicular to the transverse plane, thus making measurement of useful cross-sectional ROI ...either muscle would pose diffi- culty for determining whole ...
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Supraspinatus muscle elasticity measured with real time shear wave ultrasound elastography correlates with MRI spectroscopic measured amount of fatty degeneration
... supraspinatus muscle was detected using conventional ultrasound (b-mode) and this area was marked using a gel capsule ...supraspinatus muscle was performed with a Siemens Acuson S3000 ultrasound system ...
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A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies
... Previously, our laboratory demonstrated that knockdown of zebrafish FKRP mRNA resulted in a spec- trum of pathologies ranging from mild (slight tail curvature) to severe (extreme myofiber disruption, head malformation, ...
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