Muscle Derived Stem Cells
Original Article Skeletal muscle-derived stem cells differentiate into hepatocyte-like cells and aid in liver regeneration
... of stem cells isolated from post-natal skeletal muscle tissue has been investigated for its impressive mutlilineage differentiation ca- pacity and self-renewal ability ...These cells were ...
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Muscle derived stem cells in the treatment of anal sphincter injury in a rat model: An interventional study
... use Muscle Derived Stem Cells (MDSC) in the treatment of anal sphincter injury was by Kang et ...the muscle fibres that had regenerated had in fact developed from the implanted ...
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Effects of sildenafil and/or muscle derived stem cells on myocardial infarction
... skeletal muscle-derived stem cells (MDSC) exerts some of these ...and stem cells in combination were found to be more effective in non-MI cardiac repair than each treatment ...6 ...
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Original Article Neonatal mice muscle-derived stem cells differentiate into Schwann cell-like cells in vitro
... Muscle-derived stem cells (MDSCs) are consid- ered to be distinct from satellite cells as they may not be restricted to the myogenic lineage or mesenchymal tissues, and can ...
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Terminal differentiation is not a major determinant for the success of stem cell therapy - cross-talk between muscle-derived stem cells and host cells
... when muscle-derived stem cells (MDSCs) are implanted into a variety of tissues only a small fraction of the donor cells can be found within the regenerated tissues and the vast majority ...
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Effects of SW033291 on the myogenesis of muscle-derived stem cells and muscle regeneration
... precursor cells leads to decreased myotube formation, and this can be rescued by adding PGE2 into the culture medium ...augments muscle- specific stem cell (MuSC) proliferation through PGE2/ EP4 ...
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Adult muscle-derived stem cells engraft and differentiate into insulin-expressing cells in pancreatic islets of diabetic mice
... nonadherent cells (PP8) were washed once in ice-cold PBS and collected by centrifugation at 570 × g for 10 min before freezing as pellets until ...differentiated cells, including clusters, were washed once ...
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Myostatin genetic inactivation inhibits myogenesis by muscle-derived stem cells in vitro but not when implanted in the mdx mouse muscle
... terized stem cell populations ...the cells were suspended in plating medium (PM), containing Dulbecco Modified Eagle Medium (DMEM), with 10% fetal bovine serum (FBS), 10% horse serum, and ...USA). ...
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The effect of the muscle environment on the regenerative capacity of human skeletal muscle stem cells
... host muscle 3 days before donor human stem cell transplantation does little or nothing to aug- ment donor contribution to regenerated host muscle (Figures 1 and 2 and Tables 1 and ...satellite ...
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Cell sex affects extracellular matrix protein expression and proliferation of smooth muscle progenitor cells derived from human pluripotent stem cells
... of stem cell-based therapies is whether the differentiation of stem cells in organs that do not show sex-specific morphological differences, such as various hollow organs, is also influenced by ...
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Comprehensive analysis of skeletal muscle- and bone-derived mesenchymal stem/stromal cells in patients with osteoarthritis and femoral neck fracture
... Here, we performed a comprehensive analysis with the inclusion of well-recognized MSC sources, as the bone tissue and the less recognized skeletal muscle, to deter- mine whether MSCs from these two tissues are ...
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Markers for the identification of tendon-derived stem cells in vitro and tendon stem cells in situ – update and future development
... don cells arose from the Scx + /Sox9 + progenitors ...alpha-smooth muscle actin (α-SMA, a marker for vascular muscle cells and myofibroblasts) and a constitutively ac- tive Cre driven by ...
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Evaluation of adipose-derived stem cells for tissue-engineered muscle repair construct-mediated repair of a murine model of volumetric muscle loss injury
... in VML injuries repaired with TEMR–MDC (Figure 2) or TEMR–ADSC (Figure 3) constructs, 2 months postrepair, by Masson’s trichrome staining. Figure 2A depicts the interface of retrieved engineered muscle repaired ...
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Extracellular matrix derived from human urine-derived stem cells enhances the expansion, adhesion, spreading, and differentiation of human periodontal ligament stem cells
... Mesenchymal stem cells (MSCs), which undergo self-renewal and have multilineage po- tential, can renew themselves for a long time without significant changes in phenotype and ...and muscle, making ...
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Exosomes secreted by urine-derived stem cells improve stress urinary incontinence by promoting repair of pubococcygeus muscle injury in rats
... Being essential to skeletal muscle regeneration [37, 38], SCs are rapidly activated upon injury and then re- pair the impairment. Upon activation, the expression of MyoD is significantly upregulated while Pax7 is ...
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Muscle-derived stem/progenitor cell dysfunction in Zmpste24-deficient progeroid mice limits muscle regeneration
... a muscle-specific transcription factor involved in functional skeletal muscle development and is expressed mainly in intermediate stages of myogenesis ...myogenesis, cells were cul- tured to ...
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Human Adipose Tissue Derived Stem Cells as a Source of Smooth Muscle Cells in the Regeneration of Muscular Layer of Urinary Bladder Wall
... Four groups of cells were prepared for the evaluation of SM-ADSC differentiation by gene expression. Differentiated and undifferentiated cells at three and six weeks were evaluated. Total ribonucleic acid ...
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Intraurethral co-transplantation of bone marrow mesenchymal stem cells and muscle-derived cells improves the urethral closure
... in muscle regeneration is based on fusion rather than on true differentiation [9, ...progenitor cells and angiogenesis by a paracrine mechanism ...neural stem cells [14, ...in muscle ...
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Fusion of bone marrow–derived stem cells with striated muscle may not be sufficient to activate muscle genes
... of muscle cells) detected only 2 sarcoglycan- positive fibers; all cardiomyocytes contain- ing donor-derived nuclei were sarcoglycan ...BM-SP stem cells can produce δ−sarcoglycan but do ...
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Biological Characteristics of Foam Cell Formation in Smooth Muscle Cells Derived from Bone Marrow Stem Cells
... in cells leads to the formation of foam cells, a pathological feature of atherosclerosis [23, ...vascular cells, can specifically mediate the uptake of ox-LDL ...smooth muscle cells of ...
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