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Muscle-invasive bladder cancer (MIBC)

Chemoradiotherapy in octogenarians as primary treatment for muscle invasive bladder cancer

Chemoradiotherapy in octogenarians as primary treatment for muscle invasive bladder cancer

... for muscle-invasive bladder cancer (MIBC), in octogenarians cystec- tomy results in a higher perioperative mortality rate ...a bladder- sparing regimen composed of transurethral ...

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A case of isolated rectal recurrence of muscle invasive bladder cancer

A case of isolated rectal recurrence of muscle invasive bladder cancer

... to MIBC, specifically the need to investigate hematuria in the right clinical context and to offer neoadju- vant cisplatin based chemotherapy to all patients with ...after muscle invasive ...

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Rehabilitation interventions to improve patient-reported outcomes and physical fitness in survivors of muscle invasive bladder cancer: a systematic review protocol

Rehabilitation interventions to improve patient-reported outcomes and physical fitness in survivors of muscle invasive bladder cancer: a systematic review protocol

... Introduction Survivors of muscle invasive bladder cancer (MIBC) experience physical and psychosocial side effects of cancer diagnosis and treatment. These negative side effects ...

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Circulating Tumour DNA in Muscle-Invasive Bladder Cancer.

Circulating Tumour DNA in Muscle-Invasive Bladder Cancer.

... Muscle-invasive bladder cancer is a heterogeneous disease with an overall poor prognosis ...in MIBC include neoadjuvant platinum-based combination chemotherapy followed by surgery, or ...

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Trimodality Bladder Preservation Therapy for Muscle-Invasive Bladder Cancer: Mansoura Experience

Trimodality Bladder Preservation Therapy for Muscle-Invasive Bladder Cancer: Mansoura Experience

... objective: Bladder preservation therapy (BPT) using a trimodality approach represents an alternative option to cystectomy inmuscle-invasive bladder cancer (MIBC) patients, also a ...

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Preoperative neutrophil to lymphocyte ratio improves recurrence prediction of non-muscle invasive bladder cancer

Preoperative neutrophil to lymphocyte ratio improves recurrence prediction of non-muscle invasive bladder cancer

... Background: This study aims to prospectively evaluate the ability of Neutrophil-to-Lymphocyte ratio (NLR) to forecast recurrence in patients with non-muscle invasive bladder cancer (NMIBC). ...

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Bladder preservation approach versus radical cystectomy for high grade non muscle invasive bladder cancer: a meta analysis of cohort studies

Bladder preservation approach versus radical cystectomy for high grade non muscle invasive bladder cancer: a meta analysis of cohort studies

... non-muscle-invasive bladder cancer ...on Cancer (AJCC) staging system, also known as the tumor node metastases (TNM) classification ...non-muscle-invasive bladder ...

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Comprehensive analysis of aberrantly expressed profiles of lncRNAs and miRNAs with associated ceRNA network in muscle- invasive bladder cancer

Comprehensive analysis of aberrantly expressed profiles of lncRNAs and miRNAs with associated ceRNA network in muscle- invasive bladder cancer

... gastric cancer, hepatocellular cancer, breast cancer and pancreatic cancer ...in bladder cancer. Furthermore, comprehensive analysis of muscle- invasive ...

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Perioperative chemotherapy for muscle invasive bladder cancer

Perioperative chemotherapy for muscle invasive bladder cancer

... There continues to be considerable controversy around the use of systemic chemotherapy for muscle-invasive bladder cancer. While there is high-level evidence for a survival benefit after ...

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Canadian Urological Association guideline: Muscle invasive bladder cancer

Canadian Urological Association guideline: Muscle invasive bladder cancer

... An expert panel of academic clinicians with experience managing patients with MIBC and metastatic bladder cancer was then gathered to facilitate guideline creation. Best practice statements were ...

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Collagen stiffness promoted non-muscle-invasive bladder cancer progression to muscle-invasive bladder cancer

<p>Collagen stiffness promoted non-muscle-invasive bladder cancer progression to muscle-invasive bladder cancer</p>

... using the limma package. Through KEGG pathway analy- sis and GSEA, the ECM – receptor interaction signaling pathway was identi fi ed. By further analyzing the Oncomine database, it was determined that 6 collagen family ...

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The natural history of secondary muscle-invasive bladder cancer

The natural history of secondary muscle-invasive bladder cancer

... Conclusion: In the current series, MIBC progression occurred among initially presenting patients with NMIBC in 6.1%. In most patients, the initial diagnosis of NMIBC is correct and muscle invasion occurs ...

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Optimal management of muscle-invasive bladder cancer &ndash; a review

Optimal management of muscle-invasive bladder cancer &ndash; a review

... RC with lymph-node dissection remains the standard treat- ment for patients with MIBC or high-risk NMIBC. Existing guidelines and practice statements dedicated to preventing perioperative complications like ...

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Canadian Urological Association guideline: Muscle invasive bladder cancer

Canadian Urological Association guideline: Muscle invasive bladder cancer

... with MIBC and metastatic bladder can- cer was then gathered to facilitate guideline ...of bladder tumor (TURBT) pathology, staging, treatment, supportive and palliative care, followup and quality of ...

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Preoperative neutrophil&ndash;lymphocyte ratio and fibrinogen level in patients distinguish between muscle-invasive bladder cancer and non-muscle-invasive bladder cancer

Preoperative neutrophil&ndash;lymphocyte ratio and fibrinogen level in patients distinguish between muscle-invasive bladder cancer and non-muscle-invasive bladder cancer

... Statistical analyses were performed using IBM SPSS Statistics for Windows, version 20.0 (IBM Corporation, Armonk, NY, USA). For intergroup comparison, data obtained from NMIBC and MIBC groups were evaluated using ...

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Outcomes of trimodality bladder sparing therapy for muscle invasive bladder cancer

Outcomes of trimodality bladder sparing therapy for muscle invasive bladder cancer

... curative bladder-sparing treatment of TMT in MIBC but given the median follow up of 21 months, these findings warrant continued surveillance to obtain longer term ...with MIBC, and in the absence of ...

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Update on the management of non muscle invasive bladder cancer

Update on the management of non muscle invasive bladder cancer

... as muscle-invasive ...to muscle invasion include large multifocal high-grade Ta, T1 tumour with concomitant CIS, presence of lympho- vascular invasion, prostatic urethral involvement or non- ...

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Patient-reported Quality of Life Outcomes in Patients Treated for Muscle-invasive Bladder Cancer with Radiotherapy ± Chemotherapy in the BC2001 Phase III Randomised Controlled Trial.

Patient-reported Quality of Life Outcomes in Patients Treated for Muscle-invasive Bladder Cancer with Radiotherapy ± Chemotherapy in the BC2001 Phase III Randomised Controlled Trial.

... or bladder cancer death or after a second primary cancer diagnosis, (ii) excluding any patients with less than two years of follow-up and (iii) excluding any patients with major protocol violations ...

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miR-133b Suppresses Invasion and Migration of Gastric Cancer Cells via the COL1A1/TGF-&beta; Axis

<p>miR-133b Suppresses Invasion and Migration of Gastric Cancer Cells via the COL1A1/TGF-&beta; Axis</p>

... To further clarify the regulatory mechanism of COL1A1 in GC development, we used GSEA pathway enrichment analysis and found that COL1A1 was significantly enriched in TGF-β signaling pathway. TGF-β can be used as a sup- ...

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CUA guidelines on the management of non muscle invasive bladder cancer

CUA guidelines on the management of non muscle invasive bladder cancer

... Using 6 clinico-pathologic parameters (grade, stage, tumour size, prior recurrence rate, presence of concomitant CIS and number of tumours), the probability of recurrence and progression of NMIBC can be calculated with ...

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