Mycobacterial Antigens
Lymphocyte proliferation to mycobacterial antigens is detectable across a spectrum of HIV associated tuberculosis
... multiple antigens were combined [4,24], this approach has the potential to increase LPA ...TB-specific antigens ESAT-6 and Ag85, and is particularly important in BCG-immunized subjects such as are prevalent ...
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Specific and Randomly Derived Immunoactive Peptide Mimotopes of Mycobacterial Antigens
... forms of cancer is well known (42, 51, 55). Although the pre- cise mechanisms of action are probably not known, it is most likely that modulation of cytokine responses is a key to such immunotherapy. Since the peptide ...
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Differential in vivo expression of mycobacterial antigens in Mycobacterium tuberculosisinfected lungs and lymph node tissues
... that mycobacterial antigens are continuously released into the infected tissue and could be responsible for the forma- tion and persistence of lesions ...[10-13]. Antigens secreted into the ...
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Antibody Responses to Mycobacterial Antigens in Children with Tuberculosis: Challenges and Potential Diagnostic Value
... of mycobacterial antigens can distinguish be- tween LTBI and TB (reviewed in reference ...new mycobacterial antigens for potential serodiagnostic ...Many mycobacterial antigens ...
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Cytomegalovirus infection modulates the phenotype and functional profile of the T cell immune response to mycobacterial antigens in older life
... Infection with Cytomegalovirus is associated with accelerated immunosenescence. Expansions of CMV-specific T cell responses have previously been demonstrated to affect the ability of T cells to respond to other ...
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In utero exposure to helminth and mycobacterial antigens generates cytokine responses similar to that observed in adults
... parasite antigens (Ags) in utero may develop altered fetal immunity that could affect subsequent responses to ...and mycobacterial antigens (PPD) in vitro compared to maternal ...and ...
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Multiple mycobacterial antigens are targets of the adaptive immune response in pulmonary sarcoidosis
... to mycobacterial antigens suggested that the recognition observed was antigen-specific, we tested the ability of the BAL-derived T cells to proliferate in response to each of the five mycobacterial ...
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Identification of Mycobacterial Antigens in Human Urine by Use of Immunoglobulin G Isolated from Sera of Patients with Active Pulmonary Tuberculosis
... cross-identified mycobacterial antigens were not found in any latent individual, indicating that the antigens are specific biomarkers for active pul- monary ...
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Age-dependent humoral responses of children to mycobacterial antigens.
... A variety of mycobacterial species, including M. avium, can be cultured from environmental sources and treated water supplies (8, 11, 15), and it has been speculated that showering may provide an aerosolized ...
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Secretion of the mycobacterial 19-kilodalton protein by Escherichia coli, a novel method for the purification of recombinant mycobacterial antigens.
... secrete mycobacterial antigens that retain their antigenicities also raises the possibility that attenuated oral vaccines for salmonella might be used to present secreted mycobacterial ...
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THE PREVALENCE OF INTRADERMAL SENSITIVITY TO VARIOUS MYCOBACTERIAL ANTIGENS IN A GROUP OF HEALTHY CHILDREN IN SOUTHEASTERN UNITED STATES
... occur mainly in populations of the warmer climates.52 In an effort to separate spe- cific from non-specific tuberculin reactions, the present study was undertaken to es- tablish the loca[r] ...
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Recognition of Stage-Specific Mycobacterial Antigens Differentiates between Acute and Latent Infections with Mycobacterium tuberculosis
... The course of an M. tuberculosis infection is very complex, with only 5 to 10% of infections thought to progress to active TB in a short time. In most infected individuals, some bacteria are believed to survive and enter ...
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Mycobacterium avium complex disease in patients with AIDS: seroreactivity to native and recombinant mycobacterial antigens
... Antibodies to Mycobacterium avium complex MAC antigens were measured by enzyme-linked immunosorbent assays and immunoblot analyses in sera from 20 patients with AIDS and disseminated MAC[r] ...
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Immunoglobulin A (IgA) and IgG serum antibodies to mycobacterial antigens in Crohn's disease patients and their relatives
... paratuberculosis whole-cell antigen, using a mixture of anti-human IgA, IgE, IgG, and IgM as second antibody, and found significantly higher reactions with sera from patients with Crohn'[r] ...
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In vivo γδ T Cell Priming to Mycobacterial Antigens by Primary Mycobacterium tuberculosis Infection and Exposure to Nonpeptidic Ligands
... Healthy rhesus 12 n.d. The expansion index was calculated as the absolute number of V82 T cells in stimulated cultures divided by the absolute number of V52 T cells in the initial cultur[r] ...
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Specificity of antibodies to immunodominant mycobacterial antigens in pulmonary tuberculosis
... RESULTS Definition of cutoff points between patient and control The titers of IgG antibodies in human sera were determined in groups of patients with active smear-positive or smear-negat[r] ...
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Recognition of mycobacterial antigens by sera from patients with leprosy
... leprae sonic extract and antigenic recognition profiles by sera from patients with LL A and Mexican controls which recognized antigenic bands B.. tuberculosis soluble extract were probed[r] ...
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Investigating the Induction of Vaccine-Induced Th17 and Regulatory T Cells in Healthy, Mycobacterium bovis BCG-Immunized Adults Vaccinated with a New Tuberculosis Vaccine, MVA85A
... to mycobacterial antigens were associated with higher CD4 ⴙ CD25 hi CD39 ⴙ T-cell levels in the periphery and a reduced capacity to produce IL-17A following ...to mycobacterial antigens may ...
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Tuberculous Lymphadenitis Is Associated with Enhanced Baseline and Antigen-Specific Induction of Type 1 and Type 17 Cytokines and Reduced Interleukin-1β (IL-1β) and IL-18 at the Site of Infection
... Antigens. Mycobacterial antigens, including purified protein derivative (PPD; Statens Serum Insti- tute) and recombinant early secreted antigen 6 (ESAT-6) peptide pools and culture filtrate protein 10 ...
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Production, characterization, and species specificity of five monoclonal antibodies to Mycobacterium tuberculosis
... Three other antibodies, HGT 1, HGT 2, and HGT 4, all belonging to the IgGl type, recognized multiple bands and showed broad reactivity among all mycobacterial antigens tested, Escherichi[r] ...
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