Mycobacterial infection
Macrophages are a significant source of type 1 cytokines during mycobacterial infection
... Development of acquired T-helper 1 (Th1) cellular immunity is essential to the eradication of intracellular pathogens such as mycobacteria. This protective immu- nity is characterized by a polarized production of type 1 ...
8
Membrane TNF confers protection to acute mycobacterial infection
... TNF produced by macrophages, and a variety of other cells, is a major regulator of inflammation and leukocyte trafficking [15,16]. Although soluble TNF in controlling intracellular bacterial infections is uncontested, ...
9
CD36 deficiency attenuates experimental mycobacterial infection
... to mycobacterial infection are novel and somewhat unexpected, given the roles of CD36 in host defense against pathogens such as ...prevalent infection other than malaria ...human infection, it ...
17
Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection
... intermittent treatment is unclear, particularly when concentra- tions of macrolides within MAC-containing phagosomes are likely to be reduced in vivo to below bacteriostatic levels (28). For rapid- growing NTM species, ...
11
Nontuberculous Mycobacterial Infection of the Head and Neck in Immunocompetent Children: CT and MR Findings
... formed in one patient, and excisional biopsy alone was performed in five patients. Two patients un- derwent superficial parotidectomy, including exci- sion of contralateral lymph nodes in one patient. The incised or ...
7
Expression of recombinant HBD3 protein that reduces Mycobacterial infection capacity
... were recruited into the macrophage after dyeing with Auramine O. Subsequently, the mixture of rHBD3 (20 μg/ml) and M. bovis (MOI 10:1) was incubated with RAW264.7 cells for 24 h, and the cell apoptosis and death ratio ...
9
Rapidly growing mycobacterial infection: a recognized cause of early onset prosthetic joint infection
... between mycobacterial PJI and PJI caused by other pathogens, and to study the factors associated with mycobacterial PJI in- cluding factors predicting favorable clinical ...additional mycobacterial ...
9
Nontuberculous mycobacterial infection after lung transplantation: a report of four cases
... (NTM) infection in a patient in an immunosuppressed state caused by increased use of immunosuppressive or biological agents is a serious clinical ...of infection rate in lung transplant recipients is ...
7
Function of metal ion homeostasis in the cell division cycle, mitochondrial protein processing, sensitivity to mycobacterial infection and brain function
... parasites such as Mycobacterium, Salmonella and Leishmania is controlled in the mouse by a single gene on chromosome 1, designated Bcg, Ity or Lsh. A candidate gene for Bcg, designated natural resistance-associated ...
10
MicroRNA 889 Inhibits Autophagy To Maintain Mycobacterial Survival in Patients with Latent Tuberculosis Infection by Targeting TWEAK
... a mycobacterial component ...against mycobacterial infection through activation of ...and mycobacterial replication ...in mycobacterial infection are needed to confirm our ...
17
Current understanding on micro RNAs and its regulation in response to Mycobacterial infections
... Additionally, differential miRNA regulation was also reported recently in response to high virulent Myco- bacteria (M. tuberculosis) as compared to low virulent (M. smegmatis) in infected human macrophages [49]. ...
9
Download Download PDF
... with mycobacterial infection, despite sequencing all exons (although further changes: Three polymorphisms, one silent and two missense low-fre- quency variants were ...and mycobacterial ...
7
Rapid Detection of Mycobacterium tuberculosis in Respiratory Samples by Transcription Reverse Transcription Concerted Reaction with an Automated System
... Sample processing for detection of MTC in clinical sputum samples by cul- ture, TRC method, and COBAS AMPLICOR PCR. Clinical samples were ob- tained from patients diagnosed with or suspected of having a ...
5
Lessons from Mycobacterium avium complex associated pneumonitis: a case report
... Conclusion: The attempt to classify MAC-associated pneumonitis as either a classic hypersensitivity pneumonitis or a direct manifestation of mycobacterial infection is not particularly useful. Our case ...
5
PubMedCentral-PMC5122488.pdf
... The authors of prior publications have reported that idiopathic bronchiectasis has a female predilection and a high prevalence of an asthenic body morphotype, as well as an association with pulmonary nontuberculous ...
9
Trans cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis –induced inflammation and virulence
... early infection, thereby altering granuloma structure and ultimately restricting ...early infection and highlight the complex rela- tionship among the mycobacterial cell envelope, innate immune ...
9
Relationship between the presence of bronchiectasis and acute exacerbation in Thai COPD patients
... positive mycobacterial culture from the induced sputum was identified in 8 cases ...positive mycobacterial cul- ture and positive aerobic culture in sputum with the presence of CT-detected ...and ...
9
T cell and serological responses to Erp, an exported Mycobacterium tuberculosisprotein, in tuberculosis patients and healthy individuals
... subjects corresponding to latent TB infection. These results are consistent with previous findings concerning the production of IFN-γ by activated T cells, which is required for the regulation of isotype switching ...
11
Relief from Zmp1-Mediated Arrest of Phagosome Maturation Is Associated with Facilitated Presentation and Enhanced Immunogenicity of Mycobacterial Antigens
... Applied for almost a century, vaccination against M. tuber- culosis with M. bovis BCG protects poorly against pulmonary infections in adults. This inefficiency is illustrated by the ob- servation that almost all of the ...
7
Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection
... differential mycobacterial growth is associated with disease ...control mycobacterial growth was evaluated using the ...Reduced mycobacterial growth was seen among individuals with active TB compared ...
13