Mycobacterium leprae
Variation of TTC Repeat Pattern In The Dna of Mycobacterium Leprae Isolates Obtained from Archeological Bones and Leprosy Patients From East Nusa Tenggara
... that Mycobacterium leprae isolates are native bacteria of the territory of Indonesia and it can become one of the reasons why in the eastern part of Indonesia the incident rate and prevalence rate of ...
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THE IMPACT OF Mycobacterium leprae : A COMPREHENSIVE META-ANALYSIS OF THE PALEOPATHOLOGICAL LITERATURE
... suggesting Mycobacterium leprae and leprosariums primarily raged through Europe during the medieval era although this conclusion could be biased based on where bioarchaeological research occurs (Donoghue et ...
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Genotyping of Mycobacterium leprae on the Basis of the Polymorphism of TTC Repeats for Analysis of Leprosy Transmission
... in Mycobacterium leprae was examined using the bacilli obtained from residents in villages at North Maluku where ...M. leprae infections are highly endemic (as well as from patients at North Sulawesi ...
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Detection of Mycobacterium leprae infection by PCR
... Leprosy, caused by Mycobacterium leprae, is still considered a major health problem in many developing countries. It is a chronic infectious disease of skin, nasal cavity, and peripheral nerves which ...
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Inhibition of the Multiplication of Mycobacterium leprae by Vaccination with a Recombinant M. bovis BCG Strain That Secretes Major Membrane Protein II in Mice
... killed Mycobacterium leprae, Mycobacterium ...M. leprae and Mycobacterium ...M. leprae, both CD4 ⫹ T cells and CD8 ⫹ T cells play a central ...
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Molecular Epidemiology of Mycobacterium leprae as Determined by Structure Neighbor Clustering
... of Mycobacterium leprae, the causative agent of leprosy, due to difficulties with culturing of the organism and a lack of genetic heterogeneity between ...M. leprae strains from six different ...M. ...
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Rational Combination of Peptides Derived from Different Mycobacterium leprae Proteins Improves Sensitivity for Immunodiagnosis of M. leprae Infection
... stage Mycobacterium leprae infections which are the likely sources of trans- mission and cannot be identified by using the detection of antibodies against phenolic glycolipid ...M. leprae antigens ...
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Identification and Distribution of Mycobacterium leprae Genotypes in a Region of High Leprosy Prevalence in China: a 3 Year Molecular Epidemiological Study
... prevalent Mycobacterium leprae strains in Qiubei County, Yunnan Province, People’s Republic of China, where the annual detection rate of leprosy is 10-fold higher than the national average ...M. ...
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Molecular Determination of Mycobacterium leprae Viability by Use of Real Time PCR
... Mycobacterium leprae, the etiological agent of leprosy, is noncultivable on axenic ...M. leprae for clinical or experimental applications is often ...M. leprae viability determination, two ...
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Enriched whole genome sequencing identified compensatory mutations in the RNA polymerase gene of rifampicin-resistant <em>Mycobacterium leprae</em> strains
... in Mycobacterium leprae (M. leprae) is a cause of concern and poses a threat to the leprosy-control program, which might ultimately dampen the achievement of the elimination program of the ...M. ...
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Recombinant polypeptide of Mycobacterium leprae as a potential tool for serological detection of leprosy
... of Mycobacterium leprae, the causative agent of leprosy, are inad- equate as suggested by the rate of new leprosy cases ...M. leprae infection are crucial for early detection of leprosy and disease ...
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Detection of Mycobacterium leprae antigens in the sera of leprosy patients by sandwich immunoradiometric assay using monoclonal antibodies
... Detection of Mycobacterium leprae Antigens in the Sera of Leprosy Patients by Sandwich Immunoradiometric Assay Using Monoclonal Antibodies SHRIPAD A.. SENGUPTA' Central JALMA Institute F[r] ...
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The genome of Mycobacterium leprae: a minimal mycobacterial gene set
... Mycobacterium leprae, Hansens Bacillus, was the first human pathogenic bacterium to be identified, predating the discovery of the tubercle bacillus (Mycobacterium tubercu- losis) by a ...of ...
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Importance of the immune response to Mycobacterium leprae in the skin
... organism, Mycobacterium leprae (M. leprae), which primarily affects the skin and per- ipheral nerves (Walker and Lockwood ...M. leprae is a unique type of bacteria as it has a long generation ...
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Microsatellite Mapping of Mycobacterium leprae Populations in Infected Humans
... Leprosy is a chronic and debilitating disease caused by in- fection with Mycobacterium leprae. The bacteria are often found in skin lesions, but their abilities to invade the Schwann cells of the peripheral ...
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Presence of Human T-Cell Responses to the Mycobacterium leprae 45-Kilodalton Antigen Reflects Infection with or Exposure to M. leprae
... serine-rich Mycobacterium leprae antigen to stimulate peripheral blood mononu- clear cell (PBMC) proliferation and gamma interferon (IFN- ␥ ) production was measured in leprosy patients, household contacts, ...
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Diversity of Potential Short Tandem Repeats in Mycobacterium leprae and Application for Molecular Typing
... M. leprae obtained from household cases showed identical copy numbers by TTC triplet alone, but the isolates from one family contact case were divided into different genotypes by adding eight other polymorphic ...
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Mycobacterium leprae alters classical activation of human monocytes in vitro
... Background: Macrophages play a central role in the pathogenesis of leprosy, caused by Mycobacterium leprae. The polarized clinical presentations in leprosy are associated with differential immune ...
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Multiple Polymorphic Loci for Molecular Typing of Strains of Mycobacterium leprae
... of Mycobacterium leprae, the route of infec- tion, and the mode of its ...M. leprae and that successful MDT will eliminate ...M. leprae DNA in nasal swabs are being developed with the aim of ...
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Effects of Thalidomide on Intracellular Mycobacterium leprae in Normal and Activated Macrophages
... of Mycobacterium leprae from macro- ...M. leprae. Mouse peritoneal macrophages were infected with M. leprae, activated with gamma interferon and endotoxin, or nonactivated, and treated with ...
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