Mycobacterium smegmatis
Screening of Several Anti Infectives for in Vitro Activity against Mycobacterium smegmatis
... Mycobacterium smegmatis, a soil dwelling saprophyte is distantly related to ...M. smegmatis is also fast growing and colony generation occurs in two to three ...M. smegmatis. Further, to ...
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Disruption of Mycobacterium smegmatis Biofilms Using Bacteriophages Alone or in Combination with Mechanical Stress
... including Mycobacterium smegmatis, have been observed to grow in biofilms ...of Mycobacterium avium has been traced to home showers of those infected ...
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Cloning and Expression of a Novel Phytase Gene (phyMS) from Mycobacterium smegmatis
... The major concerns in phytase production as animal feed are to produce enzymes that is able to effectively release phytate phosphate in the animal digestive tract, stable to resist inactivation by heat from feed ...
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Solvent free synthesis of alkyl 2 (dialkylamino) 4 phenylthiazole 5 carboxylates derivatives and in vitro antimycobacterial activity of these compounds against Mycobacterium smegmatis
... [13]. Mycobacterium smegmatis, a soil dwelling saprophyte is a Mycobacterium model that is used to understand the pathogenesis and physiology of ...M. smegmatis is avirulent and fast ...M. ...
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Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis
... assessed as potential anti-cancer therapeutics. However, their potential utility as antimicrobials has only recently been appreciated. Therefore, to further investigate the efficacy of these compounds as antibiotics, we ...
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Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis
... in Mycobacterium smegmatis, in a gene cluster, conserved in most environmental mycobacterial ...M. smegmatis, two conserved palindromic DNA motifs were iden- ti fi ed using bioinformatics and tested ...
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Rapid Memory CD8+ T-Lymphocyte Induction through Priming with Recombinant Mycobacterium smegmatis
... recombinant Mycobacterium smegmatis strain expressing human immunodeficiency virus type 1 (HIV-1) gp120-elicited CD4 ⴙ T lymphocytes with a functional profile of helper cells as well as a CD8 ⴙ T-lymphocyte ...
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Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis
... in Mycobacterium smegmatis, in a gene cluster, conserved in most environmental mycobacterial ...M. smegmatis, two conserved palindromic DNA motifs were iden- ti fi ed using bioinformatics and tested ...
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Antibiotic Bactericidal Activity Is Countered by Maintaining pH Homeostasis in Mycobacterium smegmatis
... against Mycobacterium smegmatis and four evolutionarily divergent bacterial pathogens was blocked by conditions that worked to maintain intracellular pH ...
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A GFP strategy for efficient recombinant protein overexpression and purification in Mycobacterium smegmatis
... the Mycobacterium tuberculosis (Mtb) pathogen is due to signi fi cant di ffi culties in producing recombinant mycobacterial ...related Mycobacterium smegmatis species as a native host have been e ff ...
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Two promoters in the esx 3 gene cluster of Mycobacterium smegmatis respond inversely to different iron concentrations in vitro
... both Mycobacterium tuberculosis and Mycobacterium smegmatis has two promoters, suggesting the presence of two transcriptional ...M. smegmatis and to assess the promoter activities in wildtype, ...
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Epigallocatechin Gallate, a Green Tea Polyphenol Inhibits Mycobacterium smegmatis: In silico and In vitro Studies
... Presence of multidrug resistant strains makes treatment of tuberculosis difficult. Conventional frontline antituberculosis therapy has high incidence of treatment failure due to non-adherence and severe side effects, and ...
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A Novel Calcium Uptake Transporter of Uncharacterized P Type ATPase Family Supplies Calcium for Cell Surface Integrity in Mycobacterium smegmatis
... FIG 1 Phylogenetic tree depicting P-type ATPases families across bacterial divisions. The boldface numbers after the black triangles or line give the P-type ATPase family numbers; substrates for the characterized ...
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Enhanced Priming of Adaptive Immunity by Mycobacterium smegmatis Mutants with High-Level Protein Secretion
... make Mycobacterium bovis bacillus Calmette-Guérin (BCG) an attractive delivery vehicle for heterologous antigens (37, ...nonpathogenic Mycobacterium smegmatis has instead been used to engineer stable ...
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Small Molecule Suppression of Drug Resistance in Mycobacterium Smegmatis and Mycobacterium Tuberculosis.
... Given the success of our 2-aminobenzimidazoles (2-ABI) ability to lower the MIC of β- lactam antibiotics up to 128-fold in planktonic cultures of Mycobacterium smegmatis, an interest was piqued in ...
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mRNA Degradation Rates Are Coupled to Metabolic Status in Mycobacterium smegmatis
... M. smegmatis as a model for study of the mechanistic basis of mRNA stabilization in mycobacteria under stress ...M. smegmatis to hypoxia and carbon starva- tion and measured mRNA half-lives for a subset of ...
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High performance liquid chromatography patterns of mycolic acids as criteria for identification of Mycobacterium chelonae, Mycobacterium fortuitum, and Mycobacterium smegmatis
... High-Performance Liquid Chromatography Patterns of Mycolic Acids as Criteria for Identification of Mycobacterium chelonae, Mycobacterium fortuitum, and Mycobacterium smegmatis W.. RAY BU[r] ...
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Alkaloid extracts from Combretum zeyheri inhibit the growth of Mycobacterium smegmatis
... of mycobacterium to conventional drugs is mainly due to inadequate exposure of the TB causing organism to anti-tuberculosis drugs ...of mycobacterium strains to increase activity of their efflux pumps ...
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Inhibition of biofilm formation in Mycobacterium smegmatis by Parinari curatellifolia leaf extracts
... The objective of this study was to investigate the effects of P. curatellifolia leaf extracts on M. smegmatis biofilm formation. The effect of the extract on biofilm formation was determined after initially ...
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Chromosome Organization and Replisome Dynamics in Mycobacterium smegmatis
... M. smegmatis by using a dual-reporter strain express- ing fluorescent markers of the DNA replisome (mCherry-DnaN) and cell division septum (Wag31-green fluorescent protein [GFP]) ...
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