myelin oligodendrocyte glycoprotein
Evaluation of IL-17 Serum Level, Brain Inflammation and Demyelination in Experimental Autoimmune Encephalomyelitis C57BL/6 Mice Model with Different Doses of Myelin Oligodendrocyte Glycoprotein
... μg myelin oligodendrocyte glycoprotein in complete Freund’s adjuvant containing 4 mg/Ml Mycobacterium tuberculosis and two injections of 800 ng of pertussis toxin intraperitoneally, on day 0 and 2 ...
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Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis
... MOG: myelin oligodendrocyte glycoprotein; rMOG: recombinant rat MOG (extracellular domain); MS: multiple sclerosis; OD: optical density; PBS: phosphate buffered saline; PP-MS: primary progressive MS; ...
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Antibodies to myelin oligodendrocyte glycoprotein in HIV-1 associated neurocognitive disorder: a cross-sectional cohort study
... Another myelin protein that has been extensively stu- died in MS is myelin oligodendrocyte glycoprotein (MOG) [12]. MOG is a quantitatively minor type I transmembrane protein exclusively ...
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Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination
... the myelin oligodendrocyte glycoprotein (MOG) are associated with inflammatory demyelinating diseases of the central nervous system (CNS), such as acute disseminated encephalomyelitis (ADEM), mono- ...
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Chronic relapsing inflammatory optic neuropathy (CRION): a manifestation of myelin oligodendrocyte glycoprotein antibodies
... to myelin oligodendrocyte glycoprotein (MOG-Ab) has been proposed as a new marker of in- flammatory demyelinating diseases (IDDs) of the central nervous system (CNS) [3, ...
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Optical coherence tomography in myelin-oligodendrocyte-glycoprotein antibody-seropositive patients: a longitudinal study
... MOG-IgG: Myelin-oligodendrocyte glycoprotein antibodies; MS: Multiple sclerosis; N: Number; NCRC: NeuroCure Clinical Research Center Berlin; NMOSD: Neuromyelitis optica spectrum disorders; OCT: ...
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Myelin oligodendrocyte glycoprotein–specific T and B cells cooperate to induce a Devic like disease in mice
... Multiple sclerosis (MS) is a clinically and pathologically heterogeneous inflammatory/demyelinating disease of the CNS. In the MS variant Devic disease, lesions are predominantly found in the optic nerves and spinal cord ...
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Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein.
... MOG, myelin oligodendrocyte glycoprotein; MS, multiple sclerosis; PAD, peptidyl arginase deaminase; PCA, principal component analysis; qPCR, quantitative PCR; rhMOG, recombinant human MOG; SC, spleen ...
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Reactivity to myelin antigens in multiple sclerosis Peripheral blood lymphocytes respond predominantly to myelin oligodendrocyte glycoprotein
... major myelin proteins, myelin basic protein (MBP) and proteolipid protein (PLP), are likely to be of importance in the course of multiple sclerosis (MS), cell-mediated autoimmune responses to other ...
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Myelin Oligodendrocyte Glycoprotein Antibody Persistency in a Steroid-Dependent ADEM Case
... lesions (Fig 1F). At this attack, we searched for aquaporin 4 antibody (AQP4) and myelin oligodendrocyte glycoprotein (MOG) antibodies. AQP4 antibody was negative but anti-MOG IgG was positive ...
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Myelin/oligodendrocyte glycoprotein–deficient (MOG deficient) mice reveal lack of immune tolerance to MOG in wild type mice
... Myelin/oligodendrocyte glycoprotein (MOG), a 26- to 28-kDa glycoprotein, was first described as a tar- get antigen for the autoimmune demyelination response observed in animals immunized with ...
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Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination
... Myelin oligodendrocyte glycoprotein (MOG) is a myelin transmembrane protein exclusively expressed by oligo- dendrocytes within the central nervous system ...
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Schubart, Anna (2002): Aspects of the Immunobiology of Myelin Oligodendrocyte Glycoprotein (MOG)-induced Experimental Autoimmune Encephalomyelitis (EAE). Dissertation, LMU München: Fakultät für Biologie
... the myelin sheath is formed by an extension of the oligodendrocyte plasma membrane, which enwraps axons with multiple layers (10-150) of plasma membranes (Figure ...multilamellar myelin, which is ...
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The effect of vitamin A supplementation on stimulated T-cell proliferation with myelin oligodendrocyte glycoprotein in patients with multiple sclerosis.
... How to cite this article: Jafarirad S, Siassi F, Harirchian M, Sahraian M, Eshraghian M, Shokri F, Amani R, Bitarafan S, Mozafari S, Saboor- Yaraghi A. The effect of vitamin A supplementation on stimulated T-cell ...
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Immune profile of an atypical EAE model in marmoset monkeys immunized with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund’s adjuvant
... Background: Experimental autoimmune encephalomyelitis (EAE) in the common marmoset monkey (Callithrix jacchus) is a relevant preclinical model for translational research into immunopathogenic mechanisms operating in ...
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Immunization With Recombinant Myelin Oligodendrocyte Glycoprotein Identifies Autoreactive T Cells As A Limiting Factor In Autoreactive Germinal Center Maintenance
... of myelin oligodendrocyte glycoprotein (MOG), a commonly targeted autoAg in Multiple Sclerosis (MS), and streamlined the modification of the MOG protein’s ...
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CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin
... microglia. Myelin sheaths were in the process of disintegration and macrophages contained luxol fast blue (LFB)-stained myelin degradation prod- ...Damaged myelin had been removed from the axons and ...
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Identification of the Myelin Oligodendrocyte Glycoprotein as a Cellular Receptor for Rubella Virus
... E2 glycoprotein and MOG (7). This implied that the RV E2 glycoprotein and MOG may have a degree of protein sequence homologies and MOG may share some structural fragments with the RV E2 ...
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Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders
... that myelin oligo- dendrocyte glycoprotein (MOG), a glycoprotein localized on the outer surface of the myelin sheath and oligodendro- cytes [18], might be a target antigen in ...
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Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype
... against myelin oligodendrocyte glycoprotein (MOG) have been identified in a subgroup of pediatric patients with inflammatory demyelinating disease of the central nervous system (CNS) and in some ...
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