myeloid dendritic cells
Activation of myeloid dendritic cells, effector cells and regulatory T cells in lichen planus
... DC: dendritic cells; TLR: toll-like receptors; pDC: plasmacytoid dendritic cells; mDC: myeloid dendritic cells; IFN-α: interferon alpha; TNF-α: tumour necrosis factor ...
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Type I Interferon Released by Myeloid Dendritic Cells Reversibly Impairs Cytomegalovirus Replication by Inhibiting Immediate Early Gene Expression
... of myeloid dendritic cells (mDC) is biologically rele- vant for the inhibition of MCMV replication in vivo and in ...endothelial cells or fibroblasts with T cell subsets and/or ...
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Matrix Protein Mutant of Vesicular Stomatitis Virus Stimulates Maturation of Myeloid Dendritic Cells
... control. Cells treated with the TLR7 agonist loxoribine served as controls for the pres- ence of pDC, since mDC lack ...h, cells were harvested and stained with antibodies to the costimulatory molecules ...
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Ross River Virus Envelope Glycans Contribute to Type I Interferon Production in Myeloid Dendritic Cells
... Our results strongly suggest that viral complex/hybrid N- linked glycans promote IFN- ␣ /  responses in mDCs, which implicates a couple of potential mechanisms underlying this process. Though the mos-RRV and mam-RRV ...
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Vaginal Myeloid Dendritic Cells Transmit Founder HIV-1
... vaginal cells and tissues to elu- cidate the role of vaginal DCs in HIV-1 transmission ...Vaginal myeloid DCs that capture and transport T/F HIV-1 through vaginal mucosa efficiently transmit T/F viruses to ...
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Myeloid dendritic cells correlate with clinical response whereas plasmacytoid dendritic cells impact autoantibody development in rheumatoid arthritis patients treated with infliximab
... Although both subtypes of circulating DCs are reduced in active RA patients' peripheral blood, only mDC levels corre- lated with disease activity, suggesting a possible link to RA pathogenesis. The exact role of pDCs in ...
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Processing and Degradation of Exogenous Prion Protein by CD11c+ Myeloid Dendritic Cells In Vitro
... ScGT1-1 cells as observed by phase-contrast microscopy and immunofluorescence ...ScGT1-1 cells (Fig. 2B). The degenerated cells were sub- sequently engulfed by the DC in a manner similar to what has ...
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The antiviral compound BIT225 inhibits HIV-1 replication in myeloid dendritic cells
... cells when the source of HIV-1 was from de novo viral production, cis transfer (Fig. 2a). The antiviral effect of BIT225 increased over time following MDDC infec- tion, such that increased exposure to BIT225 ...
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Analysis of Plasmacytoid and Myeloid Dendritic Cells in Nasal Epithelium
... of dendritic cell precursors into the airway epithelium and that the initial wave of dendritic cell precursors arrives in advance of the neutrophil ...the dendritic cell precursors remain within the ...
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Original Article Immature CD11c+ myeloid dendritic cells with inflammatory and regulatory cytokine profile in human seminoma
... Th17 cells by secreting large number of IL-23p19, IL-6 and TNF-α, which results in IL-17 and IFN-γ-driven inflammation ...sertoli cells (Figure 4M) and IL-6 was localized in the cyto- plasm and nucleus of ...
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Interaction of Rotavirus with Human Myeloid Dendritic Cells
... T cells stimulated by RV (median, ...T cells were detected after stimula- tion with both RV and RV-infected MDC ...T cells secreting IL-2 was higher after stimulation of T cells with ...
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M27 Expressed by Cytomegalovirus Counteracts Effective Type I Interferon Induction of Myeloid Cells but Not of Plasmacytoid Dendritic Cells
... and myeloid dendritic cells compared with plasmacytoid den- dritic cell cultures, whereas plasmacytoid dendritic cells mounted more vigorous IFN-I ...of myeloid cells, ...
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Immune Activation and Regulation in Simian Immunodeficiency Virus-Plasmodium fragile-Coinfected Rhesus Macaques
... effector cells affect the balance between immune activation and ...blood myeloid dendritic cells (mDC) and monocytes were temporarily associated with acute parasitemic episodes and elevated ...
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Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis
... (SF) myeloid dendritic cells (mDCs) mature and release tumour necrosis factor alpha (TNF- α ) at comparable levels with healthy peripheral blood (PB) mDCs, but only SF mDCs release ...
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Targeting of Human Antigen-Presenting Cell Subsets
... These cells were stained for 1 h with 1 g/ml of the respective Nbs as well as antibodies that are directed against markers that allow discrimination of macro- phages (CD11b, CD11c, CD14), myeloid DCs ...
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Blood-derived dendritic cell vaccinations induce immune responses that correlate with clinical outcome in patients with chemo-naive castration-resistant prostate cancer
... T cells through antigen presentation since the sipuleucel-T products contained more than 60% CD3 + T cells and < 20% cells expressing the co-stimulatory molecule CD54, indicated as ...
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Distinct Intracellular Trafficking of Hepatitis C Virus in Myeloid and Plasmacytoid Dendritic Cells
... Huh7.5.1 cells and subsequently stained with anti-E2 (AP33) ...of cells staining positive for HCVcc E2 protein per 300 cells revealed that following 3 h of incubation with HCVcc, mDCs were ...
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Myeloid derived suppressor cells in transplantation: the dawn of cell therapy
... cells expressing CD80/86 that were defined as MDSCs. This study indicated that MDSCs had nonspecific immu- nosuppressive activity in vivo and in vitro involving the action of inducible nitric oxide synthase ...
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Differential Effects of Hepatitis C Virus JFH1 on Human Myeloid and Plasmacytoid Dendritic Cells
... HCV core protein has been previously reported to suppress DC function (16, 46). We found that HCV core protein exhib- ited similar effects compared to HCV JFH1 on DCs, except for inhibiting TLR ligand-induced mDC IL-6 ...
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Plasmacytoid Dendritic Cell Dynamics and Alpha Interferon Production during Simian Immunodeficiency Virus Infection with a Nonpathogenic Outcome
... plasmacytoid dendritic cells (PDC) in protection against AIDS in nonpathogenic simian immunodeficiency virus (SIVagm) infection in African green monkeys ...
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