Myxoid liposarcoma
FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro
... FGF receptors were already reported to play a role in various cancers and their inhibition is effectively applied in targeted therapies with specific small molecule inhibitors [32-38]. Even in sarcomas a role of FGF ...
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Single metastasis of myxoid liposarcoma from the thigh to thyroid gland: a case report
... but myxoid lipo- sarcoma is recognized to metastasize to unusual locations such as soft tissue, retroperitoneum, and spine ...that myxoid liposarcoma has a high incidence of osseous metastases and ...
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Case Report A case of myxoid liposarcoma of the breast
... [17] Antonescu CR, Tschernyavsky SJ, Decuseara R, Leung DH, Woodruff JM, Brennan MF, Bridge JA, Neff JR, Goldblum JR, Ladanyi M. Prognos- tic impact of TP53 status, TLS-CHOP fusion transcript structure, and histological ...
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A rare case of myxoid liposarcoma of the adult foot diagnosed using fine needle aspiration cytology (FNAC)
... that myxoid liposarcomas include myxoid malignant fibrous histocytomas, myxoid chondrosarcomas, dermatofibrosarcoma protuberans, and ...A myxoid malignant fibrous histocytoma contains ...
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Myxoid liposarcoma: a rare soft tissue tumor with a misleading benign appearance
... It is often well defined with little adherence to the adja- cent structures. The clinical diagnosis of malignancy of this adipose tumor is thus difficult but findings of an important size (> 5 cms) and rapidly growing ...
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Solitary metastasis of myxoid liposarcoma from the thigh to intraperitoneum: a case report
... tissue. Myxoid/round-cell liposarcoma (myx- oid liposarcoma) is one of the major subtypes of liposar- coma characterized by lipomatous differentiation with a myxoid stroma and accounts for ...
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Efficacy of first-line doxorubicin and ifosfamide in myxoid liposarcoma
... response curve, with doxorubicin given at doses of 75 mg/ m 2 and ifosfamide at 10 gm/m 2 providing the best effi- cacy-to-toxicity ratio [10-12]. As a result, this regimen was adopted a decade ago as the standard of ...
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Case Report Dendritic fibromyxolipoma of the parotid gland: a case report and review of the literature
... Lev DC, Lazar AJ, López-Terrada DH. Detection of myxoid liposarcoma-associated FUS-DDIT3 rearrangement variants including a newly identified breakpoint using an optimized RT- PCR assay. Mod Pathol 2010; 23: ...
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Case Report Retroperitoneal liposarcoma manifested as an inguinoscrotal mass: a case report
... determines the treatment and prognosis. Primarily, liposarcomas have a tendency to spread by local extension. Generally, hematog- enous and lymphatic spread is a late event associated with high-grade tumors. Atypical ...
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Clinical and Molecular Spectrum of Liposarcoma.
... Well-differentiated liposarcoma is the most common subtype and is associated with indolent behavior, local recurrence, and insensitivity to radiotherapy and ...ferentiated liposarcoma represents focal ...
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Management of Retroperitoneal Liposarcoma: A Case Report
... [2]. Liposarcoma can be histologically subdivided into five subtypes: well-differentiated, myxoid, round cell, pleomorphic and poorly differentiated ...and myxoid liposarcoma are ...
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Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and pre-operative radiation therapy
... colleagues also saw adipocytic differentiation as early as six weeks in tumors from three patients treated with tro- glitazone, a PPARγ agonist. These changes coincided with an increased expression in mRNA associated ...
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Diagnosis of extraskeletal myxoid chondrosarcoma in the thigh using EWSR1 NR4A3 gene fusion: a case report
... malignant myxoid soft tissue tumor, such as myxoid liposarcoma, myxofibrosarcoma, or metastatic carcinomas, including myoepithelial tumor and neuroendocrine tumor, and performed an incisional biopsy ...
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Case Report A chondroid lipoma in the muscle of the trunk back: a rare case report and review of the literature
... Chondroid lipomas are very rare benign lipoma- tous tumors which may be easily mistaken as myxoid liposarcoma and myxoid chondrosarco- ma. It is important for an appropriate diagnosis to avoid ...
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Dedifferentiated liposarcoma of the gallbladder: first reported case
... vides liposarcoma into four types: atypical lipomatous tumor (ALT), myxoid liposarcoma (MLS), pleomorphic liposarcoma (PL), and dedifferentiated liposarcoma (DL) ...
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Maxillofacial sarcomas: a ugandan epidemiological survey
... Neoplasm Kaposi’s sarcoma Rhabdomyosarcoma Osteosarcoma Embryonal rhabdomyosarcoma Chondrosarcoma Hemagio pericytoma Malignant fibrous hystiocytoma Myxoid liposarcoma Fibro sarcoma Derma[r] ...
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High-grade pleomorphic liposarcoma of the breast
... subtypes. Myxoid/round cell liposarcomas are characterized by translocation t(12;16) (q13;p11) fusing genes FUS at 16p11 and CHOP at 12q13 or, rarely, translocation t(12;22) (p13;q12) fusing CHOP with ...in ...
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Case Report Parachordoma/myoepithelioma of the kidney: first report of a myxoid mimicry in an unusual location
... CK. Myxoid liposarcoma was easily excluded on the morphological basis of Sudan III stain, and the detected Fus-CHOP fusion gene break-apart rearrangement was ...extraskeletal myxoid chondrosarcoma ...
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Extraskeletal myxoid chondrosarcoma with massive pulmonary metastases
... extraskeletal myxoid chondrosarcoma; TKI: tyrosine kinase inhibitor; STS: soft tissue sarcoma; NGS: next generation sequencing; TMB: tumor mutational burden; Mb: megabase; VEGF2: vascular endothelial receptor 2; ...
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Advances in the targeted therapy of liposarcoma
... study analyzing subtype-specific genomic alterations in 207 STS patients. These findings suggest a potential role for a deregulated Akt pathway in myxoid liposarcomas (MLS)/ round cell LPS (RCL) and support ...
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