N-acetyl-L-cysteine
Influence of N-acetyl-L-cysteine against bisphenol a on the maturation of mouse oocytes and embryo development: in vitro study
... [32–34]. N-Acetyl-L-cysteine (NAC) is less toxic and can increase intracellular glutathione (GSH) levels [35, 36], and GSH plays a key role in preventing oxidative stress in oocytes ...
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Suppression of methylmercury-induced MIP-2 expression by N-acetyl-l-cysteine in murine RAW264.7 macrophage cell line
... of l-cysteine, is a sulfhydryl-containing antioxidant, which has been used for the treatment of heavy metal toxicity and can act as an antiinflammatory agent ...
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Original Article Protective effect of N-Acetyl-L-Cysteine (NAC) on endosulfan-induced liver and kidney toxicity in rats
... Abstract: Endosulfan-induced systemic toxicity arises from oxidative stress and glutathione depletion. This study aims to investigate the possible protective effect of N-acetyl-L-cysteine ...
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AMELIORATIVE EFFECT OF N ACETYL L CYSTEINE ON SODIUM DICHROMATE INDUCED ALTERATIONS OF HAEMATOBIOCHEMICAL PARAMETERS IN RATS
... Protective effect of antioxidant N-acetyl-L-cysteine (NAC) on sodium dichromate induced-haemato-biochemical alterations was study. Rats were divided into four treatment groups of ten rats ...
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Direct Potentiometric Determination of N-acetyl-L-cysteine (NAC) in Real Samples by Using “home made” Iodide ISE
... N-acetyl-L-cysteine (NAC) is modified amino acid cysteine, which is synthesized in the body either in taken with food. NAC, can significantly increase the level of glutathione, an ...
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N-Acetyl L-Cysteine does not protect mouse ears from the effects of noise*
... compound N-acetyl-L-cysteine (L-NAC) can protect the hearing of chinchillas from the effects of a single exposure to ...noise. L-NAC is used in clinical medicine and is very ...
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A Comparative Assessment of Petroff’s and N-Acetyl-L-Cysteine- Sodium Hydroxide Method in the Diagnosis of Pulmonary Tuberculosis
... Tuberculosis (TB) stays one of the deadliest communicable disease and responsible for almost two million deaths every year worldwide. The objective of the present study is to compare Petroff’s and ...
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N acetyl L cysteine amide protects retinal pigment epithelium against methamphetamine induced oxidative stress
... Reliasil ODS-1 C18 column (5 µm packing material) with 250 mm × 4.6 mm i.d. (Column Engineering, Ontario, CA). The mobile phase (70% acetonitrile and 30% water) was adjusted to a pH of 2 with acetic acid and o-phosphoric ...
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Development and Validation of an Analytical Method for Related Substances in N-acetyl–L-cysteine Effervescent Tablets by RP-HPLC
... • In the present work a stability indicating high-performance liquid chromatographic method was developed for the quantification of the related substances in N-acetyl cysteine [NAC] effervescent ...
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Effects of N-acetyl-L-cysteine on Postoperative Intrabdominal Adhesion in a Large Animal Model
... under local anesthesia by 2%Lidocaine (1cc/1cm incision). The animals were prepared for aseptic surgery and positioned on left lateral recumbency. A 10 cm ventrolateral incision was made and the abdomen opened. The ...
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EFFECT OF L-PENICILLAMINE, N-ACETYL CYSTEINE AND a-TOCOPHEROL ACETATE ON BUFFALO (BUBALUS BUBALIS) SPERM KINEMATICS IN VITRO
... of L- penicillamine at 75 mM concentration increased the motility in vitro of ram sperm (El-Shahat et ...of N-acetyl-L-cysteine at 15 mM increased significantly the progressive motility ...
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Aflatoxicosis in rabbits with particular reference to its control by n acetyl cysteine and probiotic
... AFB1-mediated toxicity was also found to be related to its pro- oxidant potential. This is because reactive oxygen species (ROS) including superoxide anion (O-), hydrogen peroxide (H2O2) and hydroxyl radical (-OH) that ...
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Caffeine Protects Skin from Oxidative Stress-Induced Senescence through the Activation of Autophagy
... Co-treatment with 1 mM n-acetyl-L-cysteine (NAC), a known antioxidant, significantly suppressed the growth inhibition effect of AAPH in A375 cells ( Figure 1B , P < 0.05), confir[r] ...
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Non enzymatic upregulation of tissue factor expression by gamma-glutamyl transferase in human peripheral blood mononuclear cells
... Results: Equine GGT increased PCA, an effect insensitive to GGT inhibition by acivicin suggesting mechanisms independent of its enzymatic activity, a possibility confirmed by the maintained stimulation in response to ...
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Jingfukang induces anti cancer activity through oxidative stress mediated DNA damage in circulating human lung cancer cells
... DOC 156 kb Abbreviations AJCC: American Joint Committee on Cancer; CTCs: Circulating tumor cells; DCFH-DA: 2,7-Dichlorodihydrofluorescein diacetate; NAC: N-Acetyl-L-cysteine; NSCLC: Non-[r] ...
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N Acetyl L alanine
... other N-acetyl derivatives of the 20 common l-amino acids: N-acetylglycine (Mackay, 1975), N- acetyl-l-phenylalanine (Stout et ...2000), ...
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In vivo transfer of nitric oxide between a plasma protein bound reservoir and low molecular weight thiols
... Plasma albumin reacts with nitric oxide (NO) to form the bioactive adduct, S-nitroso-albumin (S-NO-albumin). The limited intracellular access of S-NO-albumin suggests the need for a vascular transfer mechanism of NO from ...
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Effect of N-Acetyl Cysteine on Liver Function in General Anesthesia with Isoflurane
... Toxicity with volatile anesthesia usually takes place after their decomposition in the body and this molecular decomposition results in peroxidation of fats. N-acetylcysteine (NAC) is the acetylated compound of ...
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Effect of Hypobaric Hypoxia on Cognitive Functions and Potential Therapeutic Agents
... that N-acetyl cysteine (NAC) administration during HBH exposure ameliorated the hypoxia-induced impairments in spatial working memory ...that acetyl-L-carnitine supplementation improved ...
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Simultaneous Determination of N Acetyl Cysteine and Taurine by HPTLC Method in Active Pharmaceutical Ingredient and Pharmaceutical Dosage Form
... [14] Holdiness, M.R., Morgan, L.R., Gillen, L.E. and Harrison, E.F. (1986) High Perfor- mance Liquid Chromatographic Determination of N-Acetyl Cysteine in Human Se- rum Following Acetaminophen Over ...
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