N-Acetylgalactosamine
Identification and upregulation of galactose/N acetylgalactosamine macrophage lectin in rat cardiac allografts with arteriosclerosis
... Using differential mRNA display to uncover potential mediators associated with chronic rejection, we identified a cDNA fragment induced in Lewis to F344 rat cardiac allografts with arteriosclerosis but not Lewis ...
10
Mucopolysaccharidosis type IVA N acetylgalactosamine 6 sulfate sulfatase exonic point mutations in classical Morquio and mild cases
... Mucopolysaccharidosis type IVA (MPS IVA) results from a genetic deficiency of N- acetylgalactosamine-6-sulfate (Gal-NAc6S) sulfatase. We have identified two different exonic mutations causing GalNAc6S ...
6
Polymorphisms in Tunisian patients with N-acetylgalactosamine-6-sulfate sulfatase gene deficiency: Implication in Morquio A disease
... enzyme N-acetylgalactosamine-6-sulfate sulfatase (GALNS; ...hydrolyses N-acetylga- lactosamine-6-sulfate and galactose-6-sulfate in glycosa- ...
5
N acetylgalactosamine 6 sulfate sulfatase in man Absence of the enzyme in Morquio disease
... Human N-acetylgalactosamine-6-sulfate sulfatase (6-sulfatase) activity is measured by using as a substrate a sulfated tetrasaccharide obtained by digesting purified chondroitin-6- sulfate (C-6-S) with ...
6
UDP N Acetylglucosamine 4 Epimerase Activity Indicates the Presence of N Acetylgalactosamine in Exopolysaccharides of Streptococcus thermophilus Strains
... mophilic EPS producers have been studied by homologous and heterologous expression and seem to be the determining fac- tors for EPS biosynthesis, monomer composition, and linkages (38, 39, 46, 47). These enzymes form a ...
9
Specific and differential binding of N acetylgalactosamine glycopolymers to the human macrophage galactose lectin and asialoglycoprotein receptor
... to the mannose/fucose selective human lectin Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin (DC-SIGN; CD209). The effect of sugar ligand valency on the binding (so-called ‘glycoside ...
34
A biologically active peptide mimetic of N acetylgalactosamine/galactose
... 5 mM, within the range typical of binding of sugars to lectins [11]. HPA binds to the single O-linked α-GalNAc on the serum macrophage activating factor (GcMAF) [12]. A M13 bacteriophage library consisting of randomized ...
6
Monocyte galactose/N-acetylgalactosamine-specific C-type lectin receptor stimulant immunotherapy of an experimental glioma. Part 1: stimulatory effects on blood monocytes and monocyte-derived cells of the brain
... Abbreviations: GCLRP, peptide mimetic of a ligand of C-type lectin receptor; CD, cluster of differentiation; MDCB, monocyte-derived cells of the brain; FACS, fluorescence-. activated ce[r] ...
15
Monocyte galactose/N-acetylgalactosamine-specific C-type lectin receptor stimulant immunotherapy of an experimental glioma. Part II: combination with external radiation improves survival
... Immunohistochemistry with anti-cluster of differentiation 68 confirmed fluorescence- activated cell sorting data: ( A ) the combination of cranial external radiation with adm[r] ...
10
Regulation of lutropin circulatory half life by the mannose/N acetylgalactosamine 4 SO4 receptor is critical for implantation in vivo
... The N-linked oligosaccharides on the four members of the glycoprotein hormone family contribute to the biologic function of these hormones at multiple lev- ...
9
A systematic review of new advances in the management of mucopolysaccharidosis VI (Maroteaux-Lamy syndrome): focus on galsulfase
... Mucopolysaccharidosis VI (MPS VI), also known as Maroteaux-Lamy syndrome, is caused by the deficiency of N-acetylgalactosamine-4-sulfatase (arylsulfatase B, ASB) and the resultant tissue storage of dermatan ...
10
Impact of enzyme replacement therapy and hematopoietic stem cell transplantation in patients with Morquio A syndrome
... Recombinant N-acetylgalactosamine-6-sulfate sulfatase (GALNS) in Escherichia coli BL21 (DE3) (erGALNS) and in the methylotrophic yeast Pichia pastoris (prGALNS) has been produced as an alternative to the ...
17
Characterization of simian virus 40 receptor moieties on the surfaces of Vero C1008 cells.
... Sialic acid NeuAc protein modifications in the form NeuAc-a2,3Gal-P1,3GalNAc, where Gal is galactose and GalNAc is N-acetylgalactosamine, either 0-linked or possibly as components of N-l[r] ...
6
Research, diagnosis and education in inborn errors of metabolism in Colombia: 20 years’ experience from a reference center
... GALNS: N-acetylgalactosamine-6-sulfate sulfatase; GBA: Glucocerebrosidase; GC-MS: Gas chromatography – mass spectrometry; HA: Hydroxyapatite; Hex: β -N-acetylhexosaminidases; HPLC: High performance ...
12
Recombinant antigen based avidin biotin microtiter enzyme linked immunosorbent assay for serodiagnosis of invasive amebiasis
... An immunoscreening approach was used to isolate a strongly positive cDNA clone from an Entamoeba histo- lytica HK-9 cDNA expression library in the phage vector l ZAP-II. The 1.85-kb cDNA insert was found to be truncated ...
6
Haematological Response of Broiler Chickens to Bio-control method of Aflatoxin mitigation
... Aflatoxin is toxic, carcinogenic and ubiquitous in nature affecting both crops and livestock. Mitigating aflatoxin effect using toxin binders has not been very effective. Information on the use of biological methods in ...
9
SUSTAINABILITY OF TURKEY (MELEAGRIS GALLOPAVO) PRODUCTION IN GASHUA, YOBE STATE, NIGERIA
... 13. Ogundu, U.E., Okoro, V.M.O., Okeke, G.U., Durugo, N., Mbaebie, G.A.C., Ezebuike, C.I. (2013). Effects of age, breed and sex on the serum biochemical values of Turkeys (Meleagris gallopova) in South-eastern ...
6
Crystal structure of N [3 (dimethylamino)propyl] N′,N′,N′′,N′′ tetramethyl N (N,N,N′,N′ tetramethylformamidiniumyl)guanidinium bis(tetraphenylborate)
... between 1.388 (3) and 1.506 (3) A ˚ , indicating single- and double-bond character. Furthermore, four C—N bonds have double-bond character. Here, the bond lengths range from 1.319 (3) to 1.333 (3) A ˚ . ...
17
Morphological Indices and Stepwise Regression of Koroji Sheep
... From the morphometric traits morphological indices were calculated such as Length Index (LI), Pelvic Index (PI), Body Index (BI), Proportionality (Ipr), Thoracic Develo[r] ...
6
CROP-LIVESTOCK PRODUCTION SYSTEMS CONTRIBUTIONS TO LIVESTOCK DIET AND FARMERS’ LIVELIHOOD IN IBADAN/ IBARAPA AREA, OYO STATE, NIGERIA
... The study took place in the selected locations of Oyo State of Nigeria an ethnically heterogeneous area with a high concentration of smallholder crop and livestock farmers, considered as the occupational group with a ...
9