N-Methyl- D-Aspartate
Original Article Vagus nerve stimulation causes wake-promotion by affecting neurotransmitters via orexins pathway in traumatic brain injury induced comatose rats
... (OX1R), N Methyl D Aspartate receptor-1 (NMDAR1), 5-hydroxytryptamine 2A receptor (5-HT 2A R), histamine 1 receptor (H1R), norepinephrine α1 receptor (α1-AR) were higher and gamma aminobutyric ...
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Single nanoparticle tracking of N methyl d aspartate receptors in cultured and intact brain tissue
... s, n ¼ 3253 trajectories; unspecific ¼ 3.41 s, n ¼ 46;096 trajectories; p ¼ ...specific, D ¼ 0.0448 IQR 0.01 to 0.124 μm 2 ∕s, n ¼ 3;253 trajectories; unspecific, D ¼ ...∕s, n ¼ ...
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Neuroendocrine mechanism of onset of puberty Sequential reduction in activity of inhibitory and facilitatory N methyl D aspartate receptors
... through N-methyl-D-aspartate (NMDA) ...15 d) and could no longer be observed by the end of puberty (at 50 ...(15 d), a highly potent inhibitory control of pulsatile GnRH ...
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Anti N methyl D aspartate receptor encephalitis with an imaging invisible ovarian teratoma: a case report
... Case presentation: A 25-year-old white woman with anti-N-methyl-D-aspartate receptor encephalitis presented with behavioral changes and seizures that were confirmed to be secondary to ...
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Anti N Methyl D Aspartate (NMDA) Receptor Encephalitis with Frustrated Diagnosis Course: A Case Report
... Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a rare disease with uncertain etiology and pathogenesis that affects young women. Its diagnosis can be delayed because of the nonspe- ...
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Novel hypoglycemic injury mechanism: N methyl D aspartate receptor mediated white matter damage
... (C) WM during hypoglcemia. With severe hypoglycemia, or aglycemia, energy metabolism persists until glycogen and other substrates, like glutamate, are exhausted (#1). In the absence of glucose, glutamate is consumed in ...
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Atypical presentation of anti N methyl D aspartate receptor encephalitis: two case reports
... ANA: Antinuclear antigen antibodies; beta-HCG: Beta-human chorionic gonadotropin; CSF: Cerebrospinal fluid; CT: Computed tomography; EEG: Electroencephalography; EKG: Electrocardiogram; HLA: Human leukocyte antigen; ...
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Adenosine and anoxia reduce N methyl D aspartate receptor open probability in turtle cerebrocortex
... Cortical sheets were supported by nylon mesh and held in place by a coil of platinum wire in a tissue-slice recording chamber (Fine Science Tools Inc., N. Vancouver, British Columbia). Cell-attached patch-clamp ...
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The importance of N methyl d aspartate (NMDA) receptors in subtraction of electrosensory reafference in the dorsal nucleus of skates
... At the peripheral zone of the dorsal nucleus, the somas and the apical and basal dendrites of the retrogradely labeled AENs were stained with rabbit anti-NR1 antibody (Fig.3A–D, Fig.4). The NR1 antibody staining ...
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Anti N Methyl D Aspartate Receptor Encephalitis with Concomitant Detection of Epstein Barr Virus
... Anti- N -methyl- D -aspartate receptor (NMDAR) encephalitis is a newly recog- nized leading cause of encephalitis worldwide. It is characterized by subacute cognitive and behavioural symptoms, ...
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N Methyl d Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection
... ZIKV induces massive neuronal damage of primary cultured neurons. Mecha- nisms underlying cell death induced by ZIKV have not been fully elucidated. To address this question, we prepared primary cultures of glial and ...
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Glutamate as a Neural Stress Factor in Humans and Animals
... tion of Glu and Asp by the presynaptic membrane. Glu can also be reabsorbed (reuptake) into neurons for later use [2]. Excess Glu released in synapses is con- verted to Gln (a compound devoid of excitotoxic properties) ...
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Case Report Anti-N-methyl-D-aspartate receptor encephalitis with occult ovarian teratoma: a case report
... Accumulating data suggest that tumor removal is a effective treatments for anti-NMDAR encephalitis. Dalmau et al. proposed that the tumor should be removed when present [9]. When tumor is not present, the first-line ...
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Original Article Clinical application of plasma exchange in pediatric anti-N-methyl-D-aspartate receptor encephalitis
... Abstract: Objective: To retrospectively analyze the efficacy and adverse events of plasma exchange (PE) in the treat- ment of children with anti-N-methyl-D-aspartate receptor (anti-NMDAR) ...
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The Beneficial Effect of Enriched Environment on Pathogenesis of Alzheimer’s Disease
... in N-methyl-D-aspartate receptor knockout mice and promote cog- nitive and spatial memory in aged rats via enhancing glutamate decarboxylase activity and hippocampal synaptic density [111] ...
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Meta analyses of nine polymorphisms of six genes with the risk of schizophrenia
... [9]. N-methyl D-aspar- tate 1 (GRIN1) encodes a critical subunit of N-methyl-D- aspartate receptors (NMDAR) that plays a pivotal role in glutamate neurotransmitter ...
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AMLEORATIVE ROLE OF ESCULETIN􀇧MEDIATED RENOPROTECTION AGAINST GENTAMICIN􀇧INDUCED NEPHROTOXICITY AND POSSIBLE INVOLVEMENT OF N􀇧METHYL􀇧D􀇧ASPARTATE RECEPTORS
... In the present study, genta (100 mg/kg; i.p) was administred to Wistar rats for 7 days. After 7 days of administration of genta resulted in considerably renal damage. Histopathological examination of genta- treated rats ...
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AMELIORATIVE EFFECT OF PAPAIN ON BEHAVIORAL AND BIOCHEMICAL ALTERATIONS IN IN SILICO AND IN VIVO MODELS OF NEUROPATHIC PAIN IN RATS
... on N-methyl D-aspartate (NMDA) receptor down-regulation pathway by using in-silico studies and on oxidative stress in-vivo model of neuropathic pain in rats via partial sciatic nerve ligation ...
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A femtomolar acting neuroprotective peptide
... (N-methyl d-aspartate), with the beta amyloid peptide (putative cytotoxin in Alzheimer's disease), and with tetrodotoxin (electrical ...
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Original Article Effects of N-methyl-D-aspartate receptor on remifentanil-induced hyperalgesia
... hyperalgesia. N-methyl and D-aspartate-related receptor (NMDAR) is widely found in animal and plays an important role in central nerve system and ...of ...
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