N-Methyl-N-nitrosourea
A high protein moderate carbohydrate diet fed at discrete meals reduces early progression of N-methyl-N-nitrosourea-induced breast tumorigenesis in rats
... Breast cancer is the most prevalent cancer in American women. Dietary factors are thought to have a strong influ- ence on breast cancer incidence. This study utilized a meal-feeding protocol with female Sprague-Dawley ...
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Suppression of N Methyl N Nitrosourea Induced Retinal Damage in Mice by Oligonol, an Oligomerized Polyphenol Formulation
... Oligonol is a lychee fruit-derived functional food that contains oligomerized polyphenol com- pounds. Oligonol exhibits a number of beneficial biological effects, primarily due to its antioxidant activity. Retinitis ...
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Anticancer potential of nutraceutical formulation through antioxidant, anti-inflammatory, and antiproliferative mechanisms in N-methyl-N-nitrosourea-induced mammary cancer
... our previous investigation, we prepared four nutraceutical formulations (nutraceutical formulation [NF], NF fortified, self-fortified NF [SFNF], and self-fortified NF fortified cow urine distillate [SFNFCUD]) using fine ...
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Cranberry Extract as a Supplemented Food in Treatment of Oxidative Stress and Breast Cancer Induced by N-methyl-N-nitrosourea in Female Virgin Rats
... Breast cancer is the most common cancer and a major cause of death in women. The present study was designed to evaluate the antioxidant and anticancer potential of cranberry extract against ...
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Antimutagenic components in Spatholobus suberectus Dunn against N-methyl-N-nitrosourea
... against N-alkyl-N-nitrosoureas in umu ...against N-methyl-N-nitrosourea (MNU) in the Ames assay with Salmonella typhimurium strain TA1535 and to elucidate the antimutagenic ...
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EVALUATION OF THE ANTITUMOR ACTIVITY OF AYURVEDIC FORMULATION KANCHANARA GUGGULU ON N-METHYL-N-NITROSOUREA (NMU) INDUCED MAMMARY TUMOR IN SPRAGUE-DAWLEY RATS .......
... Tumor is a major health problem all over the world. In India the incidence of mammary tu- mor (Breast cancer) is on the rise and it has become the number one cancer in females. Although many drugs are available for the ...
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Modulation of N methyl N nitrosourea induced mammary tumors in Sprague–Dawley rats by combination of lysine, proline, arginine, ascorbic acid and green tea extract
... In a previous study [5] we demonstrated the antiprolifera- tive and anti-invasive potential of a specific formulation (nutrient supplement [NS]) of lysine, ascorbic acid, proline, and green tea extract on human breast ...
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Chemotherapeutic effect of Ulmus pumila leaves methanolic extract against N-methyl-N-nitrosourea-induced mammary carcinoma in female rats: An in vitro and in vivo study
... Switzerland). N-Methyl- N-nitrosourea, dimethyl sulfoxide (DMSO), penicillin, streptomycin, trypan blue, 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT), and ...
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Isolation and characterization of antimutagenic components of Glycyrrhiza aspera against N-methyl-N-nitrosourea
... against N-methyl-N-nitrosourea (MNU) based on the Ames assay with Salmonella typhimurium ...in n-hexane, carbon tetrachloride, dichloromethane, ethyl acetate, and ethanol, and each ...
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Adeno-associated virus-mediated neuroglobin overexpression ameliorates the N-methyl-N-nitrosourea-induced retinal impairments: a novel therapeutic strategy against photoreceptor degeneration
... The N-methyl-N-nitrosourea (MNU)-administered mouse is used as a pharma- cologically induced RD animal model in various therapeutic ...
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Rapid in vivo Taxotere quantitative chemosensitivity response by 4.23 Tesla sodium MRI and histo-immunostaining features in N-Methyl-N-Nitrosourea induced breast tumors in rats
... different features but not conclusive while sodium MRI signal intensities differed by SQ and IR methods mainly for apoptosis (A) and cyst (C) along with other tumor fea- tures as shown in Figure 5 (rightmost panel) and ...
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Influence of murine leukemia proviral integrations on development of N-methyl-N-nitrosourea-induced thymic lymphomas in AKR mice.
... Box 389, Smithville, Texas 78957,1 and Department of Microbiology, The University of Texas Medical Branch, Galveston, Texas 775502 The AKR mouse strain is characterized by a high inciden[r] ...
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Preventive effect of <em>Oenothera rosea</em> on N-methyl-N-nitrosourea- (NMU) induced gastric cancer in rats
... Conclusion: Considering the histopathological signs and the antioxidant activity in vivo as well as hematological and biochemical parameters of ethanolic extract of OR, we concluded t[r] ...
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TarGo: network based target gene selection system for human disease related mouse models
... Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson ...
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4 Methyl N (4 methylphenylsulfonyl) N phenylbenzenesulfonamide
... generated by twofold rotational symmetry. The N atom is located on the twofold rotation axis and has a trigonal-planar geometry. It is bonded by two S atoms of two symmetry- related 4-methylphenylsulfonyl groups ...
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Methyl 2 (N methoxycarbonylmethyl N methylsulfamoyl)benzoate
... of methyl 2-(4-methoxypyrimidin-2-ylcarbamoylsulfamoyl)benzoate, (II) (Ma et ...planar methyl ester moiety (O1/O2/C7/C8) and SO 2 group at dihedral angles of ...
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Methyl N hydroxy N (2 methylphenyl)carbamate
... products and biologically active compounds. The title compound, which was readily synthesized from (N)-(2-methyl- phenyl)hydroxylamine, act as an intermediate for the synthesis of Strobilurin fungicide ...
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N (4 Methoxy 6 methyl 1,3,5 triazin 2 yl) N methyl N′ (2,3,4 trifluorophenyl)urea
... hydrogen bonds, N—H F, N—H N, C—H O and C— H N (Desiraju & Steiner, 1999), are observed in the mol- ecule (Table 2, Fig. 1). In the crystal structure, the molecules are stacked along the a ...
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Methyl N′ cyano N (3 pyridylmethyl)imidothiocarbamate
... and N—H···N interactions (Table ...cyano N atom also accepts a third hydrogen bond that crosslinks neighboring hydrogen-bonded rings via N···H1B ...cyano N atom is a trifurcated ...
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O Methyl N phenylthiocarbamate
... of 1.6708 (11), 1.3293 (13) and 1.3288 (15) AÊ, respectively, suggest some delocalization of -electron density over the central atoms. The closest structure available for comparison is that of the O-ethyl analogue, viz. ...
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