N-Nitro-L-Arginine
Effect of Hydrogen sulphide (H2S) on the electrophysiological properties of bovine articular chondrocytes
... donor. L-Arginine was used as a substrate for nitric oxide synthases. N-ω-Nitro-L-Arginine was used as an inhibitor of nitric oxide ...with L-Glutamine and 15mM HEPES was ...
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Vasorelaxation by the Aqueous Extract of Juliana Adstringens on Rat Aortic Rings
... In endothelium-intact rings, a cumulative concentration-response curve to norepinephrine (10 -8 to 10 -5 M.) was constructed as a control response. In presence of Juliana adstringens extract (1 ml) added to the tissue ...
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Cyclic AMP induces a relaxation response in the bullfrog Rana catesbeiana, but nitric oxide does not
... Cholecystokinin octapeptide (CCK), acetylcholine (ACh) and ceruletide have been shown to produce contraction in bullfrog (Rana catesbeiana) gallbladder strips. Agents capable of relaxing the bullfrog gallbladder are less ...
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Early treatment with hydroxychloroquine prevents the development of endothelial dysfunction in a murine model of systemic lupus erythematosus
... inhibitor N ω -nitro-L-arginine methyl ester (L-NAME, 100 μM; Sigma-Aldrich) or the antioxidant ascorbic acid (10 mM, 30-minute preincubation; Sigma- ...with L-NAME and ascorbic ...
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Hypotensive effect of Gentiana floribunda is mediated through Ca++ antagonism pathway
... Results: Gf.Cr which tested positive for presence of flavonoids, saponins, sterols, tannins and terpenes caused dose-dependent (3.0-100 mg/kg) fall in arterial blood pressure (BP) of rats under anaesthesia. In rat aortic ...
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Changes in pulmonary vascular tone during exercise Effects of nitric oxide (NO) synthase inhibition, L arginine infusion, and NO inhalation
... (a) N omega-nitro-L-arginine, 20 mg/kg intravenously, a selective inhibitor of NO synthase; (b) L-arginine, 200 mg/kg intravenously, substrate for NO synthase; (c) combination of ...
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Nitric oxide synthase lies downstream from vascular endothelial growth factor induced but not basic fibroblast growth factor induced angiogenesis
... by L -arginine analogs such as N v -mono-methyl- L -arginine (L-NMMA) and L v -nitro- L -arginine methyl ester (L-NAME), while D -isomers are ...
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Original Article Nesfatin-1 acts as an inhibitory factor in human gastrointestinal smooth muscle cells in diabetes mellitus-induced delayed gastric emptying
... HGSMC isolated from the human stomach were obtained from ScienCell Research Labo- ratories (San Diego, CA, USA). Cells were grown in Smooth Muscle Cell Medium (SMCM, Cat. #1101; Beijing Yuhengfeng Biotech Co., LTD, ...
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Antidiabetic and antihypertensive effect of dehydrozingerone in model of streptozotocin induced diabetic and nω nitro l arginine methyl ester hydrochloride (l name) hypertensive rats
... of N ω -Nitro-L-arginine methyl ester (L-NAME) 40 mg/kg bw dissolved in drinking water for 4 ...and L-NAME induced diabetic hypertensive ...
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Chronic nitric oxide inhibition in utero produces persistent pulmonary hypertension in newborn lambs
... in N omega-nitro-L-arginine-treated lambs; the increase in pulmonary blood flow and decrease in pulmonary vascular resistance were markedly attenuated compared to saline-treated ...
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A role for serotonin in the antidepressant activity of NG Nitro L arginine in the rat forced swimming test
... libitum. L-NA (Sigma Aldrich Ireland), m-hydroxybenzylhydrazine dihydrochloride (NSD-1015, Sigma) metergoline (Sigma), fluoxetine hydrochloride (Eli Lilly and ...USA), N-[4- ...
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Influence of Nitric Oxide in the Central Amygdala on the Acquisition and Expression of Morphine-Induced Place Preference in Morphine Sensitized Rats
... peripheral L-arginine administration which increased both the acquisition and expression of morphine-induced behavioral sensitization in mice (Zarrindast et ...of L-arginine resulted in ...
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Protein energy malnutrition increases arginase activity in monocytes and macrophages
... ses L-arginine to urea and ornithine; the latter is the main intracellular source for the synthesis of polyamines, which are necessary for parasite ...
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L arginine abrogates salt sensitive hypertension in Dahl/Rapp rats
... oral L-arginine than salt-sensitive rats on D- ...of L-NMMA acutely decreased, whereas intravenous L-arginine rapidly increased, urinary cGMP in both ...groups. L-arginine ...
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Nitric oxide modulates peristaltic muscle activity associated with fluid circulation in the sea pansy Renilla koellikeri
... In addition, the pharmacological data with NOS inhibitors suggest that NO is endogenously generated and that two distinct nitrergic pathways may be involved. The reduction of the amplitude of peristaltic contractions and ...
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L Argininium bis(dihydrogen phosphate)
... of L-arginine dihydrate (Karle & Karle, 1964), L-arginine chloride (Mazumdar et ...1969), L-arginine hydrochloride monohydrate (Dow et al., 1970), L-arginine ...
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Antibacterial Effect of Silver Nanoparticles along with L-Arginine against P. aeruginosa
... with L-arginine were ...that L- arginine had synergistic effects on AgNPs. Furthermore, L-arginine is a non-enzymatic antioxidant that can reduce the toxic effects of ...
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Synthesis and biological evaluation of new 1,3-thiazolidine-4-one derivatives of nitro-l-arginine methyl ester
... The ferric reducing antioxidant power of the compounds was quantified by the method described by [36] with slight modifications. The compounds were tested at dif- ferent concentrations (20, 10, 5, 2.5 mg/mL). To 0.5 mL ...
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Role of endothelium derived nitric oxide in the bleeding tendency of uremia
... rats. L-NMMA injection also increased ex vivo platelet adhesion but did not affect ex vivo platelet aggregation induced by adenosine diphosphate, arachidonic acid, and calcium ionophore ...of L-NMMA on ...
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Development and Validation of a New Rp-Hplc Method For Simultaneous Estimation of N-Acetylcysteine And L – Arginine In Combined Dosage form
... The mobile phase consisting of Phosphate Buffer (pH 4.5) : Methanol (HPLC grade) were filtered through 0.45µ membrane filter before use, degassed and were pumped from the solvent reservoir in a ratio of 90:10 v/v was ...
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