N-Nitrosodiethylamine
Protective Effects of Garlic Oil on Hepatocarcinoma Induced by N-Nitrosodiethylamine in Rats
... against N-nitrosodiethylamine (NDEA)-induced hepatocarcinoma in rats, Wistar rats were gavaged with GO (20 or 40 mg/kg) for 1 week, and then were gavaged with GO and NDEA (10 mg/kg) for the next 20 ...
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Effect of Prenatal Exposure to N-Nitrosodiethylamine on the Developing Myenteric Plexuses of Wistar Rats
... (NDEA), N-nitrosopyrrolidine (NPYR) and N-nitrosopipperidine (NPIP) [5, ...article, N-nitrosodiethylamine (NDEA) was explored. Few years ago, N-Nitrosodiethylamine was considered ...
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Chemo Preventive Effect of Rutin Against N-Nitrosodiethylamine-Induced and Phenobarbital- Promoted Hepatocellular Carcinoma in Wistar Rats
... Background: In recent years, a large number of natural compounds have been identified and proved to have a potential cancer chemopreventive importance due to their strong antioxidant and cytotoxic activities. Objective: ...
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PREVENTIVE EFFECT OF LEUCAS ASPERA METHANOLIC EXTRACT ON N NITROSODIETHYLAMINE INDUCED SUB ACUTE LIVER TOXICITY IN MALE WISTAR RATS
... INTRODUCTION: N-nitrosodiethylamine (ND EA), a chemical carcinogen present in many environmental factors and food stuffs such as milk and meat products, salted fish, alcoholic beverages and a few varieties ...
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CURATIVE EFFECT OF ELEPHANTOPUS SCABER LINN ON N’ NITROSODIETHYLAMINE INDUCED HEPATOCELLULAR CARCINOMA IN EXPERIMENTAL RATS
... Chemicals: N- nitrosodiethylamine and silymarin were purchased from Sigma Chemical Co. MO, USA. 5, 5 dithiobis-{2-nitrobenzoic acid} (DTNB), bovine serum albumin, 1-chloro-2,4 dinitrobenzene (CDNB) and ...
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Chemopreventive effect of Phyllanthus polyphyllus against N-nitrosodiethylamine induced liver tumors in wistar rats
... The aim of the study is to evaluate the chemopreventive effect of methanol extract of Phyllanthus polyphyllus (MPP) against N-nitrosodiethylamine (DEN, 200mg/kg) induced experimental liver tumors in male ...
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Protective Effect of Ethanolamine on Hepatic Preneoplastic Alterations Induced by the Administration of N Nitrosodiethylamine in Rats
... DOI: 10.4236/fns.2017.810067 940 Food and Nutrition Sciences Figure 2. Histopathological observation of the liver resected from a rat administered N -nitrosodiethylamine. (a) Clear cell foci and fibrotic ...
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N–nitrosodiethylamine cytochrome P450 induction and cytotoxicity evaluation in primary cultures of rat hepatocytes
... The primary routes of potential human exposure to N-nitrosodiethylamine (NDEA) are ingestion, inhala- tion, and dermal contact. Air, diet and smoking con- tribute to potential human exposure at levels of a ...
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Protection of liver from n nitrosodiethylamine induced hepatocellular carcinogenesis by a novel flavonol–luteolin
... to N-nitosodiethylamine induced rats provides protection against the oxidative stress caused by the carcinogen and thereby prevents hepatocellular ...to N-nitrosodiethylamine induced group of rats ...
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EFFECT OF CICHORIUM INTYBUS LEAVES ON N NITROSODIETHYLAMINE INDUCED HEPATOTOXICITY IN WISTAR RATS
... on N- nitrosodiethylamine induced hepatotoxicity, which is commonly present in foods, beverages, tobacco smoke, herbicides, pesticides, drinking water, and industrial ...
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Antioxidant and Hepatoprotective Eect of Cajanus cajan in N-Nitrosodiethylamine-Induced Liver Damage
... N-Nitrosodiethylamine (NDEA), a nitrosamine compound is a popular hepatotoxin and carcinogen causing liver damage [1]. They can be found in industrial processes, foodstuffs such as meat and milk, ...
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Umbelliferone and esculetin protect against N-nitrosodiethylamine-induced hepatotoxicity in rats
... 3.2 Effect of Umb and Esc on NDEA-induced lipid peroxidation To understand how Umb and Esc are acting to protect liver cells against NDEA, levels of lipid hydroperoxide LPO in liver were[r] ...
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CITRAL ATTENUATES N NITROSODIETHYLAMINE INDUCED LIVER CARCINOGENESIS IN EXPERIMENTAL WISTAR RATS
... The major causes of HCC are known as hepatitis B or C virus infection, food additives, alcohol, fungal toxins (aflatoxins), toxic industrial chemicals, air and water pollutants 4, 5 . Recent studies have indicated that ...
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Garlic Oil Suppressed Nitrosodiethylamine-Induced Hepatocarcinoma in Rats by Inhibiting PI3K-AKT-NF-κB Pathway
... N-nitrosodiethylamine (NDEA) is one of the most important environmental carcinogens, usually existing in cheese, soybean, processed meats, alco- holic beverages, tobacco products, cosmetics and ag- ...
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PHYTO-PHARMACOLOGICAL PROFILE OF BAUHINIA VARIEGATA
... B. variegata (EBV) was evaluated in N-nitrosodiethylamine (DEN, 200 mg/kg) induced experimental liver tumor in rats and human cancer cell lines. Oral administration of ethanol extract of B. variegata (250 ...
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Vol 48, No 1 (2018)
... The tolerance level of human exposure to nitrosamines varies between 5-10 μg/kg body weight. In many countries a program for monitoring the concentration of volatile nitrosamines in food is applied; for example, a ...
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CROP-LIVESTOCK PRODUCTION SYSTEMS CONTRIBUTIONS TO LIVESTOCK DIET AND FARMERS’ LIVELIHOOD IN IBADAN/ IBARAPA AREA, OYO STATE, NIGERIA
... The study took place in the selected locations of Oyo State of Nigeria an ethnically heterogeneous area with a high concentration of smallholder crop and livestock farmers, considered as the occupational group with a ...
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EFFECT OF MULTI-STAGE INCUBATOR TYPES ON HATCHABILITY AND CHICK QUALITY OF BROILER CHICKEN
... (2014).The effects of different eggshell temperatures on embryonic development, hatchability, chick quality and first-week broiler performance. Meeting embryonic requirement of bro[r] ...
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Effect of Leptadinea reticulata and chromium yeast (LAYPLUSR) Supplementation on the Growth and Haematological parameters of Japanese Quails (Coturnix coturnix japonica)
... Final body weight, average daily gain and feed conversion ratio indicated that Leptidenia reticulata and chromium yeast (LRCY) combination was effective in improving the[r] ...
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PREVALENCE OF SUBCLINICAL MASTITIS AND ITS MICROORGANISMS IN LACTATING COWS AT SATKHIRA DISTRICT OF BANGLADESH
... This research was committed to evaluate the prevalence of bovine subclinical mastitis for isolation and identification of the microbial agents and predisposing factors associ[r] ...
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