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n/sup +/-i-p/sup +/ injecting junction

Combined Therapeutic Effects of 131I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer

<p>Combined Therapeutic Effects of <sup>131</sup>I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer</p>

... 131 I and PEG-PLA- 131 I PEG-PLA-5Fu and PEG-PLA were labeled with 131 I via the chemical iodide ...131 I was added into PEG-PLA-5Fu or PEG-PLA (10 mg/mL, 1 ...131 I was removed by ...

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An integrated safety analysis of combined acetaminophen and ibuprofen (Maxigesic&reg;/ Combogesic&reg;) in adults

<p>An integrated safety analysis of combined acetaminophen and ibuprofen (Maxigesic<sup>&reg;</sup>/ Combogesic<sup>&reg;</sup>) in adults</p>

... Phase I clinical trials, 14 AEs were reported within 72 hours of drug administration amongst 10 patients (Table ...Phase I clinical trials had no reported AEs. During the other five Phase I studies, ...

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Comparison of head-mounted perimeter (imo&reg;) and Humphrey Field Analyzer

<p>Comparison of head-mounted perimeter (imo<sup>&reg;</sup>) and Humphrey Field Analyzer</p>

... Spearman’s rank-order correlation coefficient was calculated for correlations between HFA and i-H type, i-F type, and i-T. Bland–Altman plots were used to analyze the systematic errors of both; a ...

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IN.PACTTM AdmiralTM drug-coated balloons in peripheral artery disease: current perspectives

<p>IN.PACT<sup>TM</sup> Admiral<sup>TM</sup> drug-coated balloons in peripheral artery disease: current perspectives</p>

... DEEP trial, a total of 358 patients mostly with CLI were randomized to IN.PACT Amphirion DCB treatment group or BA treatment group. Coprimary efficacy outcomes were TLR and angiographic LLL at 12 months, and the primary ...

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Outcome Of MicroPulse&reg; Transscleral Photocoagulation In Different Types Of Glaucoma

<p>Outcome Of MicroPulse<sup>&reg;</sup> Transscleral Photocoagulation In Different Types Of Glaucoma</p>

... The statistical analysis was performed using IBM ’ s SPSS for Windows (version 22). Figures were created using Microsoft Excel ® 2013 (Microsoft Corporation, Redmond, WA, USA). The normality of the data was assessed ...

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Radiation therapy-induced reactive oxygen species specifically eliminates CD19+&nbsp;IgA+&nbsp;B cells&nbsp;in nasopharyngeal carcinoma

<p>Radiation therapy-induced reactive oxygen species specifically eliminates CD19<sup>+</sup>&nbsp;IgA<sup>+</sup>&nbsp;B cells&nbsp;in nasopharyngeal carcinoma</p>

... cells sup- press in fl ammation by secreting anti-microbial antibodies, whereas CD19 + CD138 − IgA + cells negatively regulate anti- tumor effectors by expressing PD-1 and producing TGF- β ...

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A Synthetic Peptide 2Abz23S29 Reduces Bacterial Titer and Induces Pro-Inflammatory Cytokines in a Murine Model of Urinary Tract Infection

<p>A Synthetic Peptide 2Abz<sup>23</sup>S<sup>29</sup> Reduces Bacterial Titer and Induces Pro-Inflammatory Cytokines in a Murine Model of Urinary Tract Infection</p>

... Since cytokines can play a pivotal role in the devel- opment and spread of the immune response to bacterial infections, in this study, we also examined the levels of pro-in fl ammatory cytokines including, MIP/2, IL-6, ...

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Pretreatment detection of circulating and tissue CD133+&nbsp;CD44+ cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer

<p>Pretreatment detection of circulating and tissue CD133<sup>+&nbsp;</sup>CD44<sup>+</sup> cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer</p>

... Descriptive data in the form of mean, median, range, SD, and percentages were used. Mann–Whitney U-test was used to find a relation between two groups of ordinal variables, chi-squared test between ≥ 2 groups of ...

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Designing of CD8+ and CD8+-overlapped CD4+ epitope vaccine by targeting late and early proteins of human papillomavirus

Designing of CD8<sup>+</sup> and CD8<sup>+</sup>-overlapped CD4<sup>+</sup> epitope vaccine by targeting late and early proteins of human papillomavirus

... In total, 80 CTL epitopes were predicted from the early proteins E1 (19), E2 (17), E4 (01), E6 (05), and E7 (14), and late proteins L1 (07) and L2 (17) of HPV45 based on MHC class I supertype by NetCTL 1.2 ...

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Laser-based measurements of 18O/16O stable isotope ratios (&delta;18O) in wine samples

Laser-based measurements of <sup>18</sup>O/<sup>16</sup>O stable isotope ratios (&delta;<sup>18</sup>O) in wine samples

... A commercial, OA-ICOS liquid water isotope analyzer (LWIA, Los Gatos Research, Mountain View, CA, USA) was used to measure natural waters, prepared ethanol-in-water standards, p[r] ...

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Safety And Efficacy Of Princess® FILLER Lidocaine In The Correction Of Nasolabial Folds

<p>Safety And Efficacy Of Princess<sup>®</sup> FILLER Lidocaine In The Correction Of Nasolabial Folds</p>

... Subjects received the initial treatment to both NLFs on day 0, with an optional touch-up treatment at week 2, if the investigator was not satis fi ed with the result of the fi rst treatmen[r] ...

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Evaluating Nephrocheck&reg; as a Predictive Tool for Acute Kidney Injury

<p>Evaluating Nephrocheck<sup>&reg;</sup> as a Predictive Tool for Acute Kidney Injury</p>

... The p-proteins block the effect of the cyclin-dependent protein kinase complexes (CyclD-CDK4 and CyclE-CDK2) on the cell cycle promotion, resulting in G1 cell-cycle ...

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Remicade&reg;&nbsp;(infliximab):&nbsp;20 years of contributions to science and medicine

<p>Remicade<sup>&reg;</sup>&nbsp;(infliximab):&nbsp;20 years of contributions to science and medicine</p>

... ACCENT I and II trials for luminal and fi stulizing disease, ...ACCENT I or 5 mg/kg in ACCENT II) or placebo maintenance q8w for 1 ...ACCENT I, at crossover, the dose was administered upon symptom ...

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Comparison of outcomes of conventional WaveLight&reg; Allegretto Wave&reg; and Technolas&reg; excimer lasers in myopic laser in situ keratomileusis

Comparison of outcomes of conventional WaveLight<sup>&reg;</sup> Allegretto Wave<sup>&reg;</sup> and Technolas<sup>&reg;</sup> excimer lasers in myopic laser in situ keratomileusis

... PlanoScan algorithm has a 240 Hz video-based infrared eye tracker with active x-and y-axis and passive z-axis tracking, and static compensation of cyclotorsion occurring when the patient moves from the upright to the ...

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Tobramycin administered by the TOBI&reg; Podhaler&reg; for persons with cystic fibrosis: a review

Tobramycin administered by the TOBI<sup>&reg;</sup> Podhaler<sup>&reg;</sup> for persons with cystic fibrosis: a review

... Notes: Gray circles, subjects randomized to receive 112 mg TiP twice daily; black circles, subjects randomized to receive 300 mg TiS twice daily; open circles, subjects randomized to receive matching placebo treatment ...

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Downregulation of CD44 reduces doxorubicin resistance of CD44+CD24- breast cancer cells

Downregulation of CD44 reduces doxorubicin resistance of CD44<sup>+</sup>CD24<sup>-</sup> breast cancer cells

... We carried out primary culture of 21 tumors from 21 differ- ent patients, 15 samples exhibiting tumors that had grown with many single cells surrounding the tumor tissue. Cells from 15 samples were left to freely ...

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Developments in administration of growth hormone treatment: focus on Norditropin&reg; Flexpro&reg;

Developments in administration of growth hormone treatment: focus on Norditropin<sup>&reg;</sup> Flexpro<sup>&reg;</sup>

... available in three doses, ie, 5 mg/1.5 mL, 10 mg/1.5 mL, and 15 mg/1.5 mL (Figure 1). The pen device must be refrigerated prior to first use, but after initial use, the pen devices can then either be stored outside of ...

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Partial sciatic nerve ligation leads to an upregulation of Ni2+-resistant T-type Ca2+ currents in capsaicin-responsive nociceptive dorsal root ganglion neurons

<p>Partial sciatic nerve ligation leads to an upregulation of Ni<sup>2+</sup>-resistant T-type Ca<sup>2+</sup> currents in capsaicin-responsive nociceptive dorsal root ganglion neurons</p>

... ricated from borosilicate glass capillaries (Science Products, Hofheim, Germany) using a P-97 Flaming/Brown Micro- pipette Puller (Sutter Instrument Company, Novato, CA, USA). One cell per culture dish was ...

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N-n-butyl haloperidol iodide inhibits H2O2- induced Na+/Ca2+-exchanger activation via the Na+/H+ exchanger in rat ventricular myocytes

<em>N</em>-n-butyl haloperidol iodide inhibits H<sub>2</sub>O<sub>2</sub>- induced Na<sup>+</sup>/Ca<sup>2+</sup>-exchanger activation via the Na<sup>+</sup>/H<sup>+</sup> exchanger in rat ventricular myocytes

... Fisher Scientific (Waltham, MA, USA). Anti-MEK, anti- phosphorylated (p)-MEK, anti-ERK, and anti-p-ERK antibodies were from Cell Signaling Technology (Danvers, MA, USA), anti- NCX from Santa Cruz ...

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An Immunoscore System Based On CD3+ And CD8+ Infiltrating Lymphocytes Densities To Predict The Outcome Of Patients With Colorectal Adenocarcinoma

<p>An Immunoscore System Based On CD3<sup>+</sup> And CD8<sup>+</sup> Infiltrating Lymphocytes Densities To Predict The Outcome Of Patients With Colorectal Adenocarcinoma</p>

... Overall, 106 patients with colorectal cancer were included (Table 1). The sex ratio (Men/Women: 64/ 42) was equal to 1.5 and the mean age for Men was 62.07 years [33 to 84 years], whereas for Women it was 61.98 years [25 ...

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