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n/sup +/-p/sup +/-p structure

Combined Therapeutic Effects of 131I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer

<p>Combined Therapeutic Effects of <sup>131</sup>I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer</p>

... The morphology and size distribution of nanoparticles were detected through TEM and DLS. As shown in Figure 1A, the obtained Cet-PEG-PLA-5Fu- 131 I nanoparticles showed uni- form size distribution with spherical shape. ...

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Daily consumption of the collagen supplement Pure Gold Collagen&reg; reduces visible signs of aging

<p>Daily consumption of the collagen supplement Pure Gold Collagen<sup>&reg;</sup> reduces visible signs of aging</p>

... hydrochloride (vitamin B6), extract of black pepper (Piper nigrum), copper, borage seed (Borago officinalis) oil, glycerol, soy lecithin, biotin soybean polysaccharide, malic acid, ascorbic acid (vitamin C), hyaluronic ...

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Efficacy and safety of tiotropium + olodaterol maintenance treatment in patients with COPD in the TONADO&reg; and OTEMTO&reg; studies: a subgroup analysis by age

<p>Efficacy and safety of tiotropium + olodaterol maintenance treatment in patients with COPD in the TONADO<sup>&reg;</sup> and OTEMTO<sup>&reg;</sup> studies: a subgroup analysis by age</p>

... years, n=749; 65 years to ,75 years, n=674; 75 years to ,85 years, n=186; $85 years, n=12) in OTEMTO and 5,162 patients (40 years to ,65 years, n=2,654; 65 years to ,75 years, ...

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PD-L1 in Lung Adenocarcinoma: Insights into the Role of 18F-FDG PET/CT

<p>PD-L1 in Lung Adenocarcinoma: Insights into the Role of <sup>18</sup>F-FDG PET/CT</p>

... Immunohistochemistry (IHC) staining was performed on 5- μ m thick formalin- fi xed, paraf fi n-embedded slides obtained from lung adenocarcinoma tissue. Antigen retrie- val was performed using EDTA buffer (pH 9.0) ...

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XEN&reg; Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma

<p>XEN<sup>&reg;</sup> Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma</p>

... In a prospective multicenter open-label study, Fea et al 33 compared 298 patients with Xen 45 solo (n=115) and Xen 45 combo (n=56) at 1-year results with 171 patients under- going more than 9 months ...

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An Immunoscore System Based On CD3+ And CD8+ Infiltrating Lymphocytes Densities To Predict The Outcome Of Patients With Colorectal Adenocarcinoma

<p>An Immunoscore System Based On CD3<sup>+</sup> And CD8<sup>+</sup> Infiltrating Lymphocytes Densities To Predict The Outcome Of Patients With Colorectal Adenocarcinoma</p>

... Overall, 106 patients with colorectal cancer were included (Table 1). The sex ratio (Men/Women: 64/ 42) was equal to 1.5 and the mean age for Men was 62.07 years [33 to 84 years], whereas for Women it was 61.98 years [25 ...

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Addition Of A Sleeve To The Etanercept Autoinjector (Enbrel&reg; MyClic&reg;) Improves Ease Of Use In Patients With Rheumatoid Arthritis

<p>Addition Of A Sleeve To The Etanercept Autoinjector (Enbrel<sup>&reg;</sup> MyClic<sup>&reg;</sup>) Improves Ease Of Use In Patients With Rheumatoid Arthritis</p>

... Patients and methods: Twenty-four adult patients (16 female) with RA and varying degrees of manual dexterity impairment took part in this user study. Written informed consent was supplied by each patient prior to ...

8

RNA m6A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway

<p>RNA m<sup>6</sup>A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway</p>

... attention. N 6 -methyladenosine (m 6 A), one of the most abundant and reversible modi fi cation on mes- senger RNA, was identi fi ed more than forty years ...

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Assessment of Acceptability and Ease of Use of Haemoglobin Spray (Granulox&reg;) in the Management of Chronic Wounds

<p>Assessment of Acceptability and Ease of Use of Haemoglobin Spray (Granulox<sup>&reg;</sup>) in the Management of Chronic Wounds</p>

... The concept of topical oxygen application has been investi- gated for many years. There are several ways oxygen may penetrate through the skin, which has porous and nonporous regions. Oxygen is a small molecule and can ...

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Solutol&reg;HS15+pluronicF127 and Solutol&reg;HS15+pluronicL61 mixed micelle systems for oral delivery of genistein

<p>Solutol<sup>&reg;</sup>HS15+pluronicF127 and Solutol<sup>&reg;</sup>HS15+pluronicL61 mixed micelle systems for oral delivery of genistein</p>

... shell structure. 30 This structure consists of the drugs being physi- cally incorporated into the micelles ’ hydrophobic inner cores by means of hydrophobic interactions while retaining the basic ...

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Comparing radiopaque markers and 13C-labelled breath test in diabetic gastroparesis diagnostics

<p>Comparing radiopaque markers and <sup>13</sup>C-labelled breath test in diabetic gastroparesis diagnostics</p>

... radiographer to produce pictures of suf fi cient quality. Our experience was that image quality sometimes was below the desired levels. This may have several explanations, such as different radiographers performing the ...

9

Calibrated measurement of acuity, color and stereopsis on a Nintendo&reg; 3DS&trade; game console

<p>Calibrated measurement of acuity, color and stereopsis on a Nintendo<sup>&reg;</sup> 3DS&trade; game console</p>

... A new game for the autostereoscopic screen on the Nintendo 3DS provided results that correlated well with conventional clinical tests of monocular near visual acuity, stereopsis and red [r] ...

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An integrated safety analysis of combined acetaminophen and ibuprofen (Maxigesic&reg;/ Combogesic&reg;) in adults

<p>An integrated safety analysis of combined acetaminophen and ibuprofen (Maxigesic<sup>&reg;</sup>/ Combogesic<sup>&reg;</sup>) in adults</p>

... Analysis of the safety data pooled from multiple repeated- dose Phase II/III clinical studies illustrates the excellent tolerability and safety of multiple FDC APAP/IBP oral tablet dos[r] ...

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Cost-effectiveness of adding Endocuff&reg; to standard colonoscopies for interval colorectal cancer screening

<p>Cost-effectiveness of adding Endocuff<sup>&reg;</sup> to standard colonoscopies for interval colorectal cancer screening</p>

... Conclusion: Endocuff ® for screening colonoscopies was expected to reduce interval CRC incidence and death, improve QoL, and be cost-effective to the device purchaser and cost- saving to[r] ...

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TearCare&reg; system extension study: evaluation of the safety, effectiveness, and durability through 12 months of a second TearCare&reg; treatment on subjects with dry eye disease

<p>TearCare<sup>&reg;</sup> system extension study: evaluation of the safety, effectiveness, and durability through 12 months of a second TearCare<sup>&reg;</sup> treatment on subjects with dry eye disease</p>

... the P-values were the result of separate tests of whether the mean difference = 0 for each follow-up time ...the P-values were from simple mixed-effects linear models (with no covariates) that allow for ...

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P53 Mutant p53N236S Regulates Cancer-Associated Fibroblasts Properties Through Stat3 Pathway

<p>P53 Mutant p53<sup>N236S</sup> Regulates Cancer-Associated Fibroblasts Properties Through Stat3 Pathway</p>

... Our previous study showed that p53 S/S mice manifested to an early onset of sarcomas that metastasized to various organs, such as liver and lung. 15 We attempted to under- stand the phenotypes resulting from the p53S ...

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Improving fluid resuscitation in pediatric shock with LifeFlow&reg;: a retrospective case series and review of the literature

<p>Improving fluid resuscitation in pediatric shock with LifeFlow<sup>&reg;</sup>: a retrospective case series and review of the literature</p>

... The Pediatric Advanced Life Support (PALS) Provider Manual speci fi cally calls for a 20 mL/kg fl uid bolus to be given over 5 mins for severe shock with hypovolemia or hypotension, noting[r] ...

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A Synthetic Peptide 2Abz23S29 Reduces Bacterial Titer and Induces Pro-Inflammatory Cytokines in a Murine Model of Urinary Tract Infection

<p>A Synthetic Peptide 2Abz<sup>23</sup>S<sup>29</sup> Reduces Bacterial Titer and Induces Pro-Inflammatory Cytokines in a Murine Model of Urinary Tract Infection</p>

... Since cytokines can play a pivotal role in the devel- opment and spread of the immune response to bacterial infections, in this study, we also examined the levels of pro-in fl ammatory cytokines including, MIP/2, IL-6, ...

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BetaEval Global: Prospective, Multinational, Observational Cohort Study of Patients Using BETACONNECT&reg;

<p>BetaEval Global: Prospective, Multinational, Observational Cohort Study of Patients Using BETACONNECT<sup>&reg;</sup></p>

... Conclusion: Overall, the results from BetaEval Global demonstrated that in this cohort of patients with RRMS or CIS on interferon beta-1b, use of the BETACONNECT autoinjector was associa[r] ...

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Evaluating Nephrocheck&reg; as a Predictive Tool for Acute Kidney Injury

<p>Evaluating Nephrocheck<sup>&reg;</sup> as a Predictive Tool for Acute Kidney Injury</p>

... deceased donor. 23 were diagnosed with DGF. There were no differences in age, gender, causes of end-stage renal disease, ischemic time, or degree of HLA mismatch between the patients with early graft function and DGF. In ...

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