N-terminal
Requirement of the N-Terminal Activation Domain of Herpes Simplex Virus ICP4 for Viral Gene Expression
... and N-terminal 520 and 274 amino acids, ...the N-terminal 210 amino acids of ICP4 are required for interactions with components of TFIID and mediator and, as a consequence, are necessary for ...
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Dissecting the Role of the N-Terminal Domain of Human Immunodeficiency Virus Integrase bytrans-Complementation Analysis
... an N-terminal domain is mixed with an IN from which the com- plete N-terminal domain has been removed, since no oli- gomerization can happen between the two mutant ...the ...
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Analysis of Mason-Pfizer Monkey Virus Gag Domains Required for Capsid Assembly in Bacteria: Role of the N-Terminal Proline Residue of CA in Directing Particle Shape
... The N-terminal proline of CA plays a critical role in defin- ing the structure assembled by ...the N terminus of CA from its adjacent sequences, HIV-1 CA undergoes a confor- mational change that ...
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Adenovirus Proteins II. N-Terminal Amino Acid Analysis
... the same type this N-terminal amino acid was The two fractions obtained after sucrose gradi- not found, suggesting that N-terminal methionine ent centrifugation of acetone-disrupted aden[r] ...
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Maternal type 1collagen N terminal telopeptide levels in severe hyperemesis gravidarum
... carboxyl terminal fragments, called telo- peptides, are bound to collagens with cross links and can be released into the circulation and excreted in the ...collagen N-terminal telopeptide (NTx) level ...
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The Functional Characterization of the N-terminal Domains of TUT4
... Once mutation of the N-terminal active site residues to alanine was confirmed by sequencing, all 4 mutants were transformed into BL21 C+ E. coli cells. Cells were grown to an OD600 of 0.6, followed by ...
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The N Terminal Membrane Spanning Domain of the Escherichia coli DNA Translocase FtsK Hexamerizes at Midcell
... FIG 1 Schematic representation of FtsK and its localization during cell divi- sion. (A) Diagrams representing the E. coli FtsK protein. The top diagram depicts the wild-type protein, while the bottom diagrams represent ...
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Improving the N-terminal diversity of sansanmycin through mutasynthesis
... the N- (MX-9) and the C-terminus (MX-10) respectively were ...the N-terminus to produce corresponding derivatives MX-7 and MX-8, ...the N-terminal amino acid, suggesting the precursors added ...
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Functional characterization of the N-terminal and C-terminal domains of a sesame group II phytocystatin
... Background: Phytocystatins are natural inhibitors of cysteine protease, and may regulate endo- or exo-genous proteolytic activities in plants. They are classified into Group I and II differing by the presence of ...
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The Ancestral N Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets
... hydrophobic N-terminal domain adopts a unique globular fold, and the C-terminal domain adopts a  -defensin-like ...hydrophobic N-terminal domain and are not impaired at high salt ...
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Characterization of the Redox Transition of the XRCC1 N-Terminal Domain.
... The DNA Polymerase Beta construct used for all experiments on the X1NTD-DNA Polymerase Beta complex contained amino acids 88-335 of full length DNA Polymerase Beta with a N-terminal hexa-histidine affinity ...
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Functional Analysis of N-Terminal Residues of Ty1 Integrase
... In the intragenic complementation analysis, the mutants in- I28A and in-V45A demonstrated nearly normal levels of trans- position when coexpressed with WT IN. Although this result seems contradictory to the GST pulldown ...
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Crystal Structure of the Oligomerization Domain of the Phosphoprotein of Vesicular Stomatitis Virus
... The N-terminal and C-terminal domains of SeV P bind N, while the central domain (residues 320 to 446) is responsible for oligomerization of a tetramer, as shown in the crystal struc- ture ...
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Monomeric annexin A2 is an oxygen-regulated toll-like receptor 2 ligand and adjuvant
... human ANXA2m (69 μM; AbD Serotec and Aviva Systems Biology), 6.5 μg/ml purified bovine ANXA2t (69 μM, Meridian), 5 μg/ml imiquimod, 2.6 μg/ml hu annexin A5 (69 μM, AbD Serotec), or 200 μg/ml ANXA2-OVA ...
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Production of antibodies of predetermined specificity against herpes simplex virus DNA polymerase and their use in characterization of the enzyme.
... Also shown is the remaining polymerase activity when 10 ,ul of N-terminal serum preincubated with equal volumes of N-terminal peptide or peptide 2 coupled to BSA was used.. HSV-1 % Neutr[r] ...
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Regulation of SAGA by the N-terminus of Spt7 in Saccharomyces cerevisiae
... These N- terminal tails constitute approximately 30% of the mass of histones; however they are not visible when subjected to crystallography due to their highly unstructured ...
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Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids.
... Here we demonstrate that the N-terminal region of HIV-1 Gag contains a bipartite membrane-targeting signal, consisting of the myristylated N-terminal 14 amino acids arld an additional re[r] ...
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In Situ Spatial Organization of Potato Virus A Coat Protein Subunits as Assessed by Tritium Bombardment
... the N-terminal residues form a separate domain, but this model was rejected because the tritium label- ing of the 2-strand (amino acids 17 to 20) is rather low and it does not fit well with structural ...
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Molecular basis for the control of motor-based transport of MHC class II compartments
... The N-terminal portion of ORP1L, consisting of the ankyrin repeat region (ANK; aa 1–237; ...the N-terminal Rab7- interacting ANK region of ORP1L suffi ces to specify this locali- ...
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Structure function analysis reveals that the Pseudomonas aeruginosa Tps4 two partner secretion system is involved in CupB5 translocation
... two N-terminal periplasmic POTRA (POlypeptide TRans- port Associated) domains and an N-terminal a-helix that is located within the ...the N-terminal helix of the trans- porter ...
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