NADH dehydrogenase
Impairment of NADH dehydrogenase and regulation of anaerobic metabolism by the small RNA RyhB and NadE for improved biohydrogen production in Enterobacter aerogenes
... the NADH dehydrogenase cluster, were knocked out in IAM1183 via the CRISPR-Cas9 gene-editing approach [28, 29] to create the double mutant IAM1183- CD (∆nuoC/∆nuoD) and triple mutant IAM1183-CDE ...
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NADH dehydrogenase of Trypanosoma brucei is important for efficient acetate production in bloodstream forms
... Trypanosoma brucei long slender bloodstream forms (BF) rely solely on glucose for their energy requirements; the glucose is metabolized primarily via glycolysis [6]. The mitochondria of these cells possess only two of ...
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Type 2 NADH Dehydrogenase Is the Only Point of Entry for Electrons into the Streptococcus agalactiae Respiratory Chain and Is a Potential Drug Target
... ABSTRACT The opportunistic pathogen Streptococcus agalactiae is the major cause of meningitis and sepsis in a newborn’s first week, as well as a considerable cause of pneumonia, urinary tract infections, and sepsis in ...
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Departure from Neutrality at the Mitochondrial NADH Dehydrogenase Subunit 2 Gene in Humans, but Not in Chimpanzees
... To test whether patterns of mitochondrial DNA (mtDNA) variation are consistent with a neutral model of molecular evolution, nucleotide sequences were determined for the 1041 bp of the NADH dehydrogenase ...
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Molecular Differentiation of Fasciola Species and Characterization of Genetic Diversity of F. gigantica Using NADH Dehydrogenase I (ND1) Gene in the Endemic Areas of Iran.
... The differential diagnosis between F. hepatica and F. gigantica infection is very important be- cause of their different transmission and epi- demiological characteristics. Fasciola hepatica and F. gigantica can ...
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A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging
... Mitochondrial dysfunction, and in particular impairment of the mitochondrial oxidative phosphorylation (OXPHOS) system, has been shown to result in various degenerative diseases and cancers [23; 24]. Deficits of the ...
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The respiratory NADH dehydrogenase of Escherichia coli
... this assertion comes from the demonstration that these soluble ubiquinone reductases can be isolated by treatment of high molecular weight type --1 NADH dehydrogenase, which itself has n[r] ...
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Mitochondrial targeting of human NADH dehydrogenase (ubiquinone) flavoprotein 2 (NDUFV2) and its association with early-onset hypertrophic cardiomyopathy and encephalopathy
... Pathogenic mutations found to affect protein localiza- tion are called mislocalization mutations. Modification in mitochondrial targeting signals can cause a protein not arriving at its final destination and eventually ...
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Molecular biology of the respiratory NADH dehydrogenase of Escherichia coli
... Page Chapter 3 Catalytic Activity of Purified and Reconstituted E.coli NADH Dehdyrogenase with different Ubiquinone Homologues INTRODUCTION 58 The Role of Ubiquinone in Electron Transpor[r] ...
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Isolated and repeated stroke-like episodes in a middle-aged man with a mitochondrial ND3 T10158C mutation: a case report
... of NADH dehydrogenase subunit 3 ( ND3 ), which has previously been thought to be associated with severe or fatal mitochondrial disorders that develop during the neonatal period or in ...
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Mitochondrial oxidase systems in neurospora
... The Mammalian-type Cytochrome System Experiments with wildtype mitochondria have shown that Neurospora has both an NADH dehydrogenase and a succinate dehydrogenase linked to the cytochro[r] ...
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Effects of tamarindus indica fruit pulp extract on abundance ofHepG2 cell lysate proteins and their possible consequential impact on metabolism and inflammation
... (UQCRC2), NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10 (NDUFA10), and NADH dehydroge- nase (ubiquinone) flavoprotein 1 (NDUFV1), were found to be reduced in abundance when HepG2 ...
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Proteomic profiling of the neurons in mice with depressive-like behavior induced by corticosterone and the regulation of berberine: pivotal sites of oxidative phosphorylation
... Further analysis revealed that many of the downregu- lated proteins caused by CORT are involved in the mito- chondrial respiratory chain. BBR also has a down- regulation effect on normal cells, but when used with ...
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A complete mitochondrial genome sequence of Asian black bear Sichuan subspecies (Ursus thibetanus mupinensis)
... ND1: NADH dehydrogenase subunit 1 gene; ND2: NADH dehy- drogenase subunit 2 gene; ND3: NADH dehydrogenase sub- unit 3 gene; ND4L: NADH dehydrogenase subunit 4L gene; ND4: ...
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Deficiency of the reduced nicotinamide adenine dinucleotide dehydrogenase component of complex I of mitochondrial electron transport Fatal infantile lactic acidosis and hypermetabolism with skeletal cardiac myopathy and encephalopathy
... rotenone-sensitive NADH oxidase, NADH-duroquinone reductase, and NADH-cytochrome c reductase) was 0-10% of controls, and NADH-ferricyanide reductase activity was 25-50% of controls in the ...
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The mitochondrial transcriptome of the anglerfish Lophius piscatorius
... Mitochondrial transcripts from L. piscatorius BF2 were generated by Ion S5 sequencing. About 145.2 mil- lion quality-filtered total RNA reads were obtained, including 510,484 reads (0.35%) unambiguously identi- fied as ...
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Mitochondrial cerebellar ataxia, renal failure, neuropathy, and encephalopathy (MCARNE)
... Mitochondrial NADH dehydrogenase 5 (MT-ND5) Asp393Asn missense mutation is estab- lished to cause mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes ...
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Electroanalytical Validation of a Novel Nanobiosensing Strategy and Direct Electrochemistry of Phenylalanine Dehydrogenase for Clinical Diagnostic Applications
... A novel and highly sensitive biosensor based on a nanocomposite consisting of starch, polyvinyl alcohol (PVA) and multi-walled carbon nanotubes (MWCNT) was first fabricated for immobilizing enzyme phenylalanine ...
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Neuromodulatory effect of solvent fractions of Africa eggplant (Solanium dadyphyllum) against KCN-induced mitochondria damage, viz. NADH-succinate dehydrogenase, NADH- cytochrome c reductase, and succinate-cytochrome c reductase
... Procedure The activities of NADH–cytochrome C re- ductase (NCR) and succinate–cytochrome C reductase (SCR) were measured in brain mitochondria as de- scribed previously [18]. Briefly mitochondrial protein (0.1 mg) ...
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Redox engineering by ectopic expression of glutamate dehydrogenase genes links NADPH availability and NADH oxidation with cold growth in Saccharomyces cerevisiae
... alcohol dehydrogenase Adh3 [35] (Fig- ure 1), plays a key role in the maintenance of the mito- chondrial redox balance ...glycerol-3-phosphate dehydrogenase [38], the enzyme encoded by GPD1 [39], and its ...
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