Nanostructured Lipid Carrier
Formulation and in-vitro drug Released Mechanism of CNS Acting Venlafaxine Nanostructured Lipid Carrier for Major Depressive Disorder
... Venlafaxine (VLX) is a first line, dual acting and unique antidepressant drug which belong to the class of serotonin and norepinephrine reuptake inhibitors. Oral administration of VLX has many adverse effects, poor ...
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Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model
... Abstract: Cancer nanotherapy is progressing rapidly with the introduction of many innovative drug delivery systems to replace conventional therapy. Although the antitumor activity of zerumbone (ZER) has been reported, ...
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Nanostructured lipid carrier surface modified with Eudragit RS 100 and its potential ophthalmic functions
... Abstract: This study was carried out to evaluate the ocular performance of a cationic Eudragit (EDU) RS 100-coated nanostructured lipid carrier (NLC). The genistein encapsulated NLC (GEN-NLC) was ...
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Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice
... in nanostructured lipid carrier (NLC) was found to be less toxic than pure ...in lipid carrier minimizes the toxicity of the ...
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Virgin coconut oil based nanostructured lipid carrier loaded with ficus deltoidea extract for skin barrier improvement
... of lipid peroxidation in ...for nanostructured lipid carrier (NLC) system in several studies (Pamudji et ...liquid lipid in NLC but also complements the system ...
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Development of ibuprofen-loaded nanostructured lipid carrier-based gels: characterization and investigation of in vitro and in vivo penetration through the skin
... ibuprofen-loaded nanostructured lipid carrier (IBU-NLC) was developed for enhanced skin penetration to improve the treatment of osteoarthritis and other musculoskeletal ...
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<p>Formulation, Preparation and Evaluation of Nanostructured Lipid Carrier Containing Naringin and Coix Seed Oil for Anti-Tumor Application Based on “Unification of Medicines and Excipients”</p>
... a nanostructured lipid carrier (NLC) with naringin (NG) containing coix seed oil (CSO) as liquid lipid based on the theory (NCNLC) in order to achieve synergistic antitumor activity against ...
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In vivo biodistribution, anti-inflammatory, and hepatoprotective effects of liver targeting dexamethasone acetate loaded nanostructured lipid carrier system
... into nanostructured lipid carrier ...novel carrier for DXMA, has potential for the treatment of liver diseases, increasing the cure efficiency and decreasing the side effects on other ...
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FORMULATION & CHARACTERIZATION OF NANOSTRUCTURED LIPID CARRIER (NLC) BASED GEL FOR TOPICAL DELIVERY OF ETORICOXIB
... loaded Nanostructured lipid carrier (NLCs) gel for topical delivery that could not only increase delivery of drug locally and improve the release of the drug for a prolonged period, but also reduce ...
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Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia cell line
... (ZER)-loaded nanostructured lipid carrier (NLC) prepared by hot high-pressure homogenization techniques in an acute human lymphoblastic leukemia (Jurkat) cell line in ...
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Nanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule
... Abstract: Nanostructured lipid carriers (NLCs) were employed to formulate a lipophilic drug into hydrophilic polymeric microneedles (MNs). Hyaluronic acid (HA) was selected as a hydrophilic and bioerodible ...
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DESIGN AND DEVELOPMENT OF BOSWELLIC ACID LOADED NANOSTRUCTURED LIPID CARRIER BASED ANTI PSORIATIC NANO GEL FOR DERMAL DELIVERY
... The Boswellic acid powder was highly crystalline it gives sharp peaks seen at the 2θ value in the x-ray scan (fig 4). It also shows the XRD patterns of freeze-dried Boswellic acid loaded NLC showing that peak intensity ...
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Development and evaluation of nanostructured lipid carrier-based hydrogel for topical delivery of 5-fluorouracil
... NLC-based drug delivery system can be targeted to the skin with reduced systemic access and side effects in comparison with conventional formulations such as cream, gel, and so on. Furthermore, the NLCs were formulated ...
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<p>Pumpkin Oil–Based Nanostructured Lipid Carrier System for Antiulcer Effect in NSAID-Induced Gastric Ulcer Model in Rats</p>
... Nanostructured lipid carriers (NLCs), second-generation solid lipid nanoparticles (SLNs), are high-performance phar- maceutical nanocarrier systems developed to enhance water solubility, stability as ...
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<p>Oleic acid-loaded nanostructured lipid carrier inhibits neutrophil activities in the presence of albumin and alleviates skin inflammation</p>
... ltration. Lipid-based drug delivery systems, such as NLC and SLN, have shown considerable promise in the cutaneous application of active ingredients that are dif fi cult to transport via conven- tional ...Moreover, ...
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<p>Methotrexate-Loaded Nanostructured Lipid Carrier Gel Alleviates Imiquimod-Induced Psoriasis by Moderating Inflammation: Formulation, Optimization, Characterization, In-Vitro and In-Vivo Studies</p>
... Optimization of MTX loaded NLCs was carried out by 3 2 factorial design to determine the effect of the two inde- pendent variables, amount of Compritol 888 (solid lipid), and amount of Capmul MCM (liquid ...
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FABRICATION, CHARACTERIZATION, AND IN VITRO EVALUATION OF PEGYLATED GLYCERIDE LABRASOL® NANOSTRUCTURED LIPID CARRIER COMPOSITES OF METHOTREXATE: THE PATHWAY TO EFFECTIVE CANCER THERAPY
... NLC carrier, primarily as an oily component and second as the PEG- containing substrate, thereby enhancing the biological half-life of the therapeutic and increasing the storage stability of nanocomposites ...
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FORMULATION AND PHYSICOCHEMICAL EVALUATION OF NANOSTRUCTURED LIPID CARRIER FOR CODELIVERY OF CLOTRIMAZOLE AND CIPROFLOXACIN
... (solid lipid polymer), oleic acid (liquid lipid polymer), and polyvinyl alcohol (surfactant) were utilized for formulating NLCs through solvent diffusion ...
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Rosuvastatin Loaded Nanostructured Lipid Carrier: For Enhancement of Oral Bioavailability
... tured lipid carrier were successfully prepared by High shear homogenisation followed by Ultra sonication ...in lipid concentration up to certain concentration range and further increase in ...
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Design of a nanostructured lipid carrier intended to improve the treatment of tuberculosis
... of the lipid nanoparticles. On the other hand, statistically sig- nificant changes in ζ -potential were observed with the manno- sylation process (P,0.05), since M-NLC and M-NLC-RFB exhibit a positive charge of + ...
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