Natural Killer
Therapeutic Depletion of Natural Killer Cells Controls Persistent Infection
... 8. Lang PA, Lang KS, Xu HC, Grusdat M, Parish IA, Recher M, Elford AR, Dhanji S, Shaabani N, Tran CW, Dissanayake D, Rahbar R, Ghazarian M, Brustle A, Fine J, Chen P, Weaver CT, Klose C, Diefenbach A, Haussinger D, ...
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Determination of natural killer cell function by flow cytometry.
... Natural killer cells (NK cells) are a subset of peripheral blood lymphocytes that mediate non-major histocompatibility complex-restricted cytotoxicity of foreign target ...
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Herpesvirus Evasion of Natural Killer Cells
... (ILCs), natural killer (NK) cells, belonging to the group I ILCs, are the best characterized population ...the natural cytotoxicity receptors (NCRs) ...of killer immunoglobulin-like receptors ...
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Transplantation and innate immunity: the lesson of natural killer cells
... Schematic representation of the main interactions occurring between normal natural killer (NK) cells (expressing both HLA class I-specific inhibitory receptors and activating receptors) and potential target ...
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Natural killer cells in human autoimmune disorders
... Natural killer (NK) cells are innate lymphocytes that play a critical role in early host defense against viruses. Through their cytolytic capacity and generation of cytokines and chemokines, NK cells ...
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Cocaine increases natural killer cell activity
... The administration of epinephrine to humans increases natural killer (NK) cell activity and numbers. If endogenous catecholamines regulate NK cells, then their activity should be increased by cocaine, an ...
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Natural killer cells and natural killer T cells in Lyme arthritis
... Natural killer T (NKT) cells, a subgroup of T cells comprising about 0.2% of lymphocytes, express surface antigens associated with both adaptive (T cell receptor) and innate (NK receptors) immunity [22]. ...
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Nasal and Nasal Type Natural Killer (NK)/T Cell Lymphoma: Immunophenotype and Epstein Barr Virus (EBV) Association
... Nasal and Nasal Type Natural Killer (Nk)/T Cell Lymphoma Immunophenotype and Epstein Barr Virus (Ebv) Association ORIGINAL ARTICLE Nasal and Nasal type Natural Killer (NK)/Y cell Lymphoma Immunophenot[.] ...
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Natural Killer Cells and Antifungal Host Response
... NK, natural killer cell; PAMP, pathogen-associated molecular pattern; PRR, pattern recognition receptor; TCR, T cell receptor; TLR, Toll-like receptor; RANTES, regulated upon activation, normal T-cell ...
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<p>Preparation of highly activated natural killer cells for advanced lung cancer therapy</p>
... Natural killer (NK) cells are a critical component of the innate immune system and are characterized by their rapid response to and strong cytotoxicity against virus- infected or malignant cells without ...
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Characterization of tumor infiltrating Natural Killer cell subset
... The presence of tumor-infiltrating Natural Killer (NK) within a tumor bed may be indicative of an ongoing immune response toward the tumor. However, many studies have shown that an intense NK infiltration, ...
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Transcriptional analysis of natural killer T cell development
... invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor ...express natural sequence variants of the canonical TCR-α and decreased affinity for self/CD1d ...
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Emerging role of Natural killer cells in oncolytic virotherapy
... Abstract: Natural killer (NK) cells constitute a subtype of lymphocytes that initiate innate immune responses against tumors and virus-infected cells. The ability of NK cells to kill target cells or to ...
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Natural Killer Cell Lymphoma in a Pediatric Patient With Inflammatory Bowel Disease
... Tumor necrosis factor ␣ (TNF- ␣ ) antibody agents are an effective ther- apy for the treatment of inflammatory bowel disease (IBD); however, because of the potential for immune suppression with these drugs, TNF- ␣ ...
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Dynamic changes of cytotoxic T lymphocytes (CTLs), natural killer (NK) cells, and natural killer T (NKT) cells in patients with acute hepatitis B infection
... RESEARCH Open Access Dynamic changes of cytotoxic T lymphocytes (CTLs), natural killer (NK) cells, and natural killer T (NKT) cells in patients with acute hepatitis B infection Jun Li1,2*?, Yaping Han[.] ...
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Natural killer cells and autoimmunity
... Murine models show that natural killer (NK) cells affect autoimmunity through several potential mechanisms. (a) NK cells limit viral-induced tissue damage by directly killing virally infected cells or by ...
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Active but not inactive granulomatosis with polyangiitis is associated with decreased and phenotypically and functionally altered CD56dim natural killer cells
... without natural cytotoxic response were all from patients in the non-remission group, except for the two patients with the lowest natural killer (NK)/target ratios within the remission group ...minor ...
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Natural Killer Cell Immunodeficiency in Siblings: Defective Killing in the Absence of Natural Killer Cytotoxic Factor Activity in Natural Killer and Lymphokine-Activated Killer Cytotoxicities
... Natural killer cells play important roles in the defense against tumor growth and viral infections.’ In the cytolytic event, natural killer cells first nec- ognize and bind to a target c[r] ...
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Exogenous Activation of Invariant Natural Killer T Cells by α Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza
... ABSTRACT Influenza A virus infection can predispose to potentially devastating secondary bacterial infections. Invariant natural killer T (iNKT) cells are unconventional, lipid-reactive T lymphocytes that ...
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Extranodal Natural Killer/T-cell Lymphoma in a Child with a Prior History of Nasal Trauma: a Case Report
... Extranodal natural killer/T-cell lymphoma (ENK/TCL) is a rare subtype of NHL with a poor prognosis that has some association with Epstein- Barr virus (EBV) (1, ...
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