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Natural Killer Cell

Autologous Natural Killer Cell/Natural Killer T Cell Immunotherapy of Malignant Diseases

Autologous Natural Killer Cell/Natural Killer T Cell Immunotherapy of Malignant Diseases

... NK cell activation, is prognostic of increased survival in breast cancer ...[17]. Natural killer cell number and/or function have been identified as independent prognostic factors in many ...

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Medullasin enhances human natural killer cell activity

Medullasin enhances human natural killer cell activity

... of natural killer cell activity by ...the natural killer cell activity of lymphocytes stimulated with ...human natural killer cell activity is regulated ...

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Induction of Natural Killer Cell Responses by Ectromelia Virus Controls Infection

Induction of Natural Killer Cell Responses by Ectromelia Virus Controls Infection

... Natural killer (NK) cells play a pivotal role in the innate immune response to viral infections, particularly murine cytomegalovirus (MCMV) and human ...NK cell cytotoxicity and/or gamma interferon ...

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Clinical utility of a novel natural killer cell activity assay for diagnosing non-small cell lung cancer: a prospective pilot study

<p>Clinical utility of a novel natural killer cell activity assay for diagnosing non-small cell lung cancer: a prospective pilot study</p>

... population, patients with benign lung disease, and non-small cell lung cancer (NSCLC) patients at Korea University Anam Hospital, between January 2016 and September 2017 and measured NKA for all groups. Healthy ...

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Natural Killer Cell Dysfunction in Hepatocellular Carcinoma: pathogenesis and clinical implications

Natural Killer Cell Dysfunction in Hepatocellular Carcinoma: pathogenesis and clinical implications

... narrow killer-cell immunoglobulin-related receptor (KIR) profile that indicates a clonal-like expansion ...receptor natural killer group 2 member A (NKG2A), which binds to the human leukocyte ...

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Pathogenesis of murine cytomegalovirus infection in natural killer cell-depleted mice.

Pathogenesis of murine cytomegalovirus infection in natural killer cell-depleted mice.

... 119 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The effect of natural killer NK cells on the course of acute and persistent murine cytomegalovirus MCMV infection wa[r] ...

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Inhibition of Human Natural Killer Cell Activity by Influenza Virions and Hemagglutinin

Inhibition of Human Natural Killer Cell Activity by Influenza Virions and Hemagglutinin

... NK cell apoptosis, as both the inac- tivated virion and HA did not increase NK cell ...target cell simulation, the activa- tion of the ␨ chain initiates a cascade signaling pathway, re- sulting in ...

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Role and Regulation of Myosin IIA in Natural Killer Cell Cytotoxicity

Role and Regulation of Myosin IIA in Natural Killer Cell Cytotoxicity

... Natural killer (NK) cells are lymphocytes of the innate immune system that provide critical defense against viral infections and ...NK cell activation takes place in a series of steps, beginning with ...

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Determination of natural killer cell function by flow cytometry.

Determination of natural killer cell function by flow cytometry.

... NK cell activity be- cause of possible correlations between NK cell activity and disease outcome or progression (6, 10, 11, 13, ...NK cell activity that could be incorporated into the evaluation of ...

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Characterization of tumor infiltrating Natural Killer cell subset

Characterization of tumor infiltrating Natural Killer cell subset

... the cell membrane, were positive for VEGF, represented as a green fluorescence, which was essentially localized in the cell cytoplasm, in both colon and breast tumor tissues and as expected, also in ...

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Lymphocyte, monocyte, and natural killer cell reference ranges in postpartal women.

Lymphocyte, monocyte, and natural killer cell reference ranges in postpartal women.

... immune cell subsets present in peripheral ...many cell subsets at 4 months in postpartal women com- pared to those in nonpostpartal women appear to indicate that recovery from the immunosuppression of ...

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PKM2 regulation of metabolism but not transcription is important for natural killer cell responses

PKM2 regulation of metabolism but not transcription is important for natural killer cell responses

... T cell receptor or antibodies, and so are different to their lymphocyte ...of natural cytotoxicity receptors (NCR) ...NK cell target cell identification is based on ‘missing ...NK cell ...

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Aggressive mature natural killer cell neoplasms: from epidemiology todiagnosis

Aggressive mature natural killer cell neoplasms: from epidemiology todiagnosis

... NK cell neoplasms comprise a wide spectrum of entities, from cases with an indolent disease course (chronic NK-cell lymphocytosis) to cases with aggressive clinical behavior (NKTCL and ...NK- cell ...

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Cocaine increases natural killer cell activity

Cocaine increases natural killer cell activity

... lymphocyte subsets, including NK cells. Intravenous cocaine (0.6 mg/kg) produced a three- to fourfold increase in NK cell activity in peripheral blood. The increase was accompanied by a marked and selective ...

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Natural Killer Cell Immunodeficiency in Siblings: Defective Killing in the Absence of Natural Killer Cytotoxic Factor Activity in Natural Killer and Lymphokine-Activated Killer Cytotoxicities

Natural Killer Cell Immunodeficiency in Siblings: Defective Killing in the Absence of Natural Killer Cytotoxic Factor Activity in Natural Killer and Lymphokine-Activated Killer Cytotoxicities

... Natural killer cells play important roles in the defense against tumor growth and viral infections.’ In the cytolytic event, natural killer cells first nec- ognize and bind to a target c[r] ...

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Natural Killer Cell Lymphoma in a Pediatric Patient With Inflammatory Bowel Disease

Natural Killer Cell Lymphoma in a Pediatric Patient With Inflammatory Bowel Disease

... Tumor necrosis factor ␣ (TNF- ␣ ) antibody agents are an effective ther- apy for the treatment of inflammatory bowel disease (IBD); however, because of the potential for immune suppression with these drugs, TNF- ␣ ...

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Unraveling human natural killer cell deficiency

Unraveling human natural killer cell deficiency

... NK cell–deficient individuals. However, NK cell deficiencies are rare, and more research is ...NK cell deficiency as mutation in the MCM4 gene, encoding minichromosome maintenance complex component ...

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The modulation of immunological activities in human NK cells by extracts of ginkgo

The modulation of immunological activities in human NK cells by extracts of ginkgo

... in natural killer (NK) cell activity and surface markers in human NK cells and by analyzing for surface ...Methods Natural killer cell activity was determined in peripheral blood ...

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First case of primary intraocular natural killer t-cell lymphoma

First case of primary intraocular natural killer t-cell lymphoma

... Case presentation: A 66 year-old woman without any systemic disease presented with blurred vision due to a severe vitreous opacity in the right eye. Flow cytometric analysis of the vitreous fluid suggested a ...

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Echinococcus multilocularis inoculation induces NK cell functional decrease through high expression of NKG2A in C57BL/6 mice

Echinococcus multilocularis inoculation induces NK cell functional decrease through high expression of NKG2A in C57BL/6 mice

... NK cells exert its function on pathogens, tumor cells, stressed hepatocytes, and HSCs via the production of cytokines (IFN-γ, TNF-α, IL-10, IL-12, IL-22, etc.) and cytotoxic molecules (granzyme B, Perforin, etc.) both in ...

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