Natural killer cells
Biology of interleukin-6 production by human natural killer cells
... Human natural killer (NK) cells are large granular lymphocytes that function predominantly as cytotoxic effector cells of the innate immune ...NK cells also function as regulators of ...
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Transplantation and innate immunity: the lesson of natural killer cells
... T cells, which, otherwise, could attack recipient-specific, either major (in large part) or minor histocompatibility, anti- gens, this resulting in extremely severe, often fatal, GVHD ...T cells in ...
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Natural killer cells responsiveness to physical exercise: A brief review
... NK cells, physical exercise and tu- mour proliferation/inhibition, a recent and very important study by Inbar et ...leukemia cells was administered, showed that when they were subjected to intermittent ...
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Recognition of Vaccinia Virus-Infected Cells by Human Natural Killer Cells Depends on Natural Cytotoxicity Receptors
... Natural killer cells are important components of the im- mune responses to many viruses, yet with the exception of NK recognition of cytomegalovirus-infected cells (17, 25), the mechanisms ...
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Natural killer cells and natural killer T cells in Lyme arthritis
... NK cells, patients with antibiotic-responsive arthritis had higher frequencies of iNKT cells in SF than PB, but these cells were often absent in SF in patients with antibiotic-refractory ...iNKT ...
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Contributions of natural killer cells to the immune response against Plasmodium
... NK cells killed iRBCs via ADCC and inhibited the growth of Plasmodium in vitro [52] ...NK cells at a 3:1 effector (NK) to target (late stage infected RBC) ratio with naïve (USA) serum or hyperimmune serum ...
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Increased CD160 expression on circulating natural killer cells in atherogenesis
... NK cells might be associated with an inflamed status in AS, which is supported by the following three ...NK cells positively correlated with the levels of serum IFN- γ , TNF- α and IL-6, three important ...
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Phenotypic and functional characterization of cord blood natural killer cells
... original cells that gave rise to the primary colony, especially when both the primary and secondary colonies are composed of multi-lineage cells (Carow et ...f cells in CB showed to be greater than ...
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Simulation of Tumor Growth Model and Its Interaction with Natural-Killer Cells and T Cells
... Tumor is a disease which is caused by abnormal growth of cells. There are two types of tumor namely benign tumor and malignant tumor (cancer). A malignant tumor or cancer is one of the eight leading causes of ...
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Intracellular Disposition of Fludarabine Triphosphate in Human Natural Killer Cells
... NK cells, and seemingly contradictory results have been ...NK cells do not require proliferation for their activity and that fludarabine exposure actually enhanced NK cell activity [12, ...-expressing ...
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Natural killer cells in patients with severe chronic fatigue syndrome
... MicroRNAs are non-coding small RNA molecules with regulatory roles in the expression of genes including translation repression or mRNA degradation [110, 111]. In CFS, NK cell expression of miR-10a, miR-21, miR-103, ...
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Natural killer cells: role in local tumor growth and metastasis
... NK cells kill tumor cells expressing MHC-I molecules or save autologous cells with absent MHC-I expression (Figure ...target cells but also the expression of inducible ligands of activating NK ...
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KLRD1-expressing natural killer cells predict influenza susceptibility
... of natural killer (NK) cells at baseline in discovery cohorts and the held-out validation ...progenitor cells (HSPCs) at ...cytotoxic cells, as KLRD1 expression at baseline correlated ...
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Natural killer cells are present in the normal human lung but are functionally impotent
... epithelial lining fluid exerted a profound suppressive effect on blood NK cell activity (P less than 0.001 for both) by inhibiting their ability to lyse target cells after binding (P less than 0.001). Though ...
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Pulmonary manifestations in Behçet disease: impaired natural killer cells activity
... BAL fluids recovered from BD patients were more cellu- lar than those from healthy controls and RA patients , containing significantly greater number of lymphocytes (P< 0.05) [Table 1]. Expression of retinoid-related ...
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Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells
... Additional studies focused on JAK family genes, since 2 of the 4 members of this family (JAK1 and JAK2) were identified in our screen. This family of kinases has been functionally well character- ized and is known to be ...
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Bench to bedside review: Natural killer cells in sepsis guilty or not guilty?
... NK cells has opened a new interest in their putative involvement in innate immune response to bacterial infections ...NK cells express the bacterial sensors TLR2, TLR4 and TLR9 at the protein level and that ...
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Alloreactivity and Association of Human Natural Killer Cells with the Major Histocompatibility Complex
... NK cells can mediate specific allogeneic target cell lysis (11); NK clones derived from single donors can recognize different al- lospecificities (12), and five different allospecificities have been defined ...
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Acute Clearance of Human Metapneumovirus Occurs Independently of Natural Killer Cells
... NK cells by flow cy- tometry in C57BL/6 (B6) mice (Jackson Laboratory) infected in- tranasally with 6 ⫻ 10 5 PFU HMPV (A2 clinical strain TN/94-49) (11) ...NK cells in mock-treated mice (inoculated with ...
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Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium
... committed cells into clonal MSCs (de Keizer, 2017; Ritschka et ...decidual cells upon uNK cell activation ensures that the embryo embeds in a prepon- derance of mature decidual ...+ cells trans- ...
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