Nd/sub 50/Fe/sub 40/Al/sub 10/
Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... g/mL, 10 µ g/mL, or 100 µ g/mL) for 24 hours in the absence or presence of N-acetylcysteine (NAC; 10 mM) (Sigma-Aldrich Co); NAC was added 3 hours before treatment with MgNPs-Fe 3 O 4 ...with ...
10
Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>@Au composite magnetic nanoparticles in vitro and in vivo
... that Fe 3 O 4 @Au composite MNPs were almost ingested and deposited in the liver because no nanoparticles and hemosiderosis were observed in other organs including heart, spleen, lung, kidney, and brain, ...
15
Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... that Fe 3 O 4 -PLGA-PEG 2000 -doxorubicin has dose-dependent and time-dependent cytotoxicity against the A549 lung can- cer cell line (IC 50 ...that Fe 3 O 4 -PLGA-PEG 3000 -doxorubicin has dose- ...
16
Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... sulfate [SDS], 20% glycerol) containing the protease inhibitor phenylmethanesulfonyl fluoride 0.1 mM/L. We separated 50 µ g of proteins on SDS–polyacrylamide gel electrophoresis 10%. Proteins were ...
8
Polyetherimide-grafted Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging
... from healthy Sprague Dawley rats was collected in heparin- coated tubes. The red blood cells (RBCs) were obtained by centrifugation at 1,500 rpm for 5 minutes, and the upper plasma was removed. The RBCs were then washed ...
13
Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... average weights of the three TiO 2 NP groups and three Fe 3 O 4 - TiO 2 NP groups were 399.16 ± 13.56 g, 401.50 ± 16.48 g, 409.80 ± 26.60 g, 427.83 ± 23.16 g, 396.71 ± 27.86 g, and 413.80 ± 25.74 g, respectively. ...
15
Magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells
... incubated in 96-well flat-bottomed plates (CoStar, Charlotte, NC). Different concentrations of adriamycin, daunorubicin, dexamethasone, MNP-Fe 3 O 4 , adriamycin + MNP-Fe 3 O 4 , daunorubicin + ...
6
Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>/DNR magnetic nanoparticles in the treatment of hematologic malignancies
... of Fe 3 O 4 ...experimental Fe 3 O 4 -MNPs/DNR groups and negative controls (P ...LD 50 of the Fe 3 O 4 -MNPs/DNR was ...experimental Fe 3 O 4 -MNPs/ DNR groups were ...Self-assembled ...
6
Biological responses to core–shell-structured Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-NH<sub>2</sub> nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy
... ± 10 g) were obtained from the SPF ...for Fe@Si NP intravenous adminis- tration: control group, low-dose 10 nm Fe@Si NP-exposure group (10L), low-dose 20 nm Fe@Si NP-exposure group ...
16
Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... The functional groups on the particles were identified by Fourier transform infrared (FT-IR) spectroscopy using a JASCO IR-4200 (JASCO Inc, Easton, MD, USA). The per- centage of Dex and alendronate that were coated onto ...
12
Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... Samples of tumor tissue weighing 0.1 g was collected from each mouse and homogenized for detection of P- glycoprotein, Bcl-2, Bax, and caspase-3. Briefly, the tissues were extracted with Triton X-100, and the proteins ...
9
The effects of magnetite (Fe<sub>3</sub>O<sub>4</sub>) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH<sub>3</sub>) cells and in RAW 264.7 macrophages
... therapeutics. Fe 3 O 4 NPs usually present super paramagnetic properties and by altering proton relaxation in the tissue microenvironment are ideal for magnetic resonance contrast ...
10
The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... with Fe 3 O 4 magnetic nanoparticles (Fe 3 O 4 -MNPs). The Fe 3 O 4 -MNPs were synthesized, and their characteristics such as particle size, zeta potential, and X-ray diffraction patterns were ...
6
Sub-10 nm Cu<sub>5</sub>FeS<sub>4</sub> cube for magnetic resonance imaging-guided photothermal therapy of cancer
... TEM was performed using a transmission electron micro- scope (JEOL JEM-2100 at 200 kV). X-ray diffraction (XRD) was carried out on a Rigaku D/MAX 2250 diffractometer with Cu/K α radiation at a scanning rate of 10 ...
10
In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... characterization, Fe m O n -SiO 2 composite flake-like and SiO 2 -Fe m O n core-shell IONPs demonstrated spherical shape with mean diameter of 98 ± 22 and 101 ± 19 nm, respectively (Figure ...2B–E). ...
11
Effect of Alkaline and Alkaline Earth Metal Oxides Addition on the Glass Formation and Crystallization of ZnO Al<sub>2</sub>O<sub>3</sub> SiO<sub>2</sub> Glasses
... surface tension [14]. As a result, surface energy decreases with temperature and the increase of surface energy is caused by the change of crystal size. The value of temperature dependence on surface energy is close to ...
13
<p>Nd<sub>2</sub>O<sub>3</sub> Nanoparticles Induce Toxicity and Cardiac/Cerebrovascular Abnormality in Zebrafish Embryos via the Apoptosis Pathway</p>
... However, there were other reasons for vascular disap- pearance. Some researchers considered that axonal trajec- tories of neurons correlated with blood vessel sprouting and formation of vascular networks. 24,25 Previous ...
14
Combination of PEI-Mn<sub>0.5</sub>Zn<sub>0.5</sub>Fe<sub>2</sub>O<sub>4</sub> nanoparticles and pHsp 70-<em>HSV</em>-<em>TK</em>/GCV with magnet-induced heating for treatment of hepatoma
... gene therapy and play a synergistic antitumor effect; the mech- anism may be as follows: 1) High temperature may increase the perfusion of capillary, then the distribution of the drug is changed with local drug ...
15
In vitro and in vivo targeting imaging of pancreatic cancer using a Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoprobe modified with anti-mesothelin antibody
... All initial reagents were obtained commercially and used as-received: sodium acetate, iron trichloride hexahydrate (FeCl 3 ⋅ 6H 2 O), ethylene glycol, ethanol, deionization water (DI water), ammonium hydroxide, ...
13
Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... After being cultured in RPMI-1640 containing 6 mg/L GA, 0.6 mg/L GA conjugated with 10 mg/L MNPs-Fe 3 O 4 or without GA at 37 ° C for 48 hours, K562 cells were collected and smeared. Some films were stained ...
9