Neonatal Alloimmune
Neonatal alloimmune thrombocytopenia
... Abstract: Neonatal alloimmune thrombocytopenia occurs in one in 1,000–1,500 live births and is the most common cause of severe thrombocytopenia and intracranial hemorrhage in term ...of neonatal ...
12
Resistance to Recombinant Human Granulocyte Colony-Stimulating Factor in Neonatal Alloimmune Neutropenia Associated With Anti-Human Neutrophil Antigen-2a (NB1) Antibodies
... ABSTRACT. Neonatal alloimmune neutropenia is the neutrophil counterpart of the erythrocyte disorder of he- molytic disease of the ...had neonatal alloimmune neutropenia associated with anti- ...
5
Neonatal Alloimmune Thrombocytopenia With Amegakaryocytosis, B Lymphopenia, and Villitis
... of neonatal alloimmune thrombocytopenia (NAIT) was not further investigated because fetal-maternal antigen incompatibility was found in the class I human platelet antigen (HPA) system (mother HPA-1a/a, ...
6
Neonatal Alloimmune Thrombocytopenia: Antenatal and Postnatal Imaging Findings in the Pediatric Brain
... PURPOSE: Neonatal alloimmune thrombocytopenia (NAIT) is a ma- ternal-fetal platelet antigen incompatibility disorder estimated to occur in one of 2000 to 5000 ...
9
Epidemiology and management of fetal and neonatal alloimmune thrombocytopenia
... and neonatal alloimmune thrombocytopenia (FNAIT) is a disease in pregnancy characterized by maternal alloantibodies directed against the human platelet antigen ...
8
Fetal and neonatal alloimmune thrombocytopenia: evidence based antenatal and postnatal management strategies.
... Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is one of the leading causes of thrombocytopenia in otherwise healthy newborns [1,2]. FNAIT results from maternal alloanti- body formation as a result ...
10
Fetal intracranial haemorrhages caused by fetal and neonatal alloimmune thrombocytopenia: an observational cohort study of 43 cases from an international multicentre registry
... and neonatal alloimmune thrombocytopenia (FNAIT) is the most common cause of intracranial haem- orrhage (ICH) in relation to thrombocytopenia in term- born ...for neonatal ICH from other ...
8
Antenatal management in fetal and neonatal alloimmune thrombocytopenia: a systematic review.
... Several strategies can be used to manage fetal or neonatal alloimmune thrombocyto- penia (FNAIT) in subsequent pregnancies. Serial fetal blood sampling (FBS) and intrauterine platelet transfusions (IUPT), ...
11
Current perspectives on fetal and neonatal alloimmune thrombocytopenia – increasing clinical concerns and new treatment opportunities
... Abstract: Differences in platelet type between the fetus and the mother can lead to maternal immunization and destruction of the fetal platelets, a condition named fetal and neonatal alloimmune ...
12
Foetal and neonatal alloimmune thrombocytopaenia
... Foetal/neonatal alloimmune thrombocytopaenia (NAIT) results from maternal alloimmunisation against foetal platelet antigens inherited from the father and different from those present in the mother, and ...
6
Neonatal alloimmune thrombocytopenia caused by anti HPA antibodies in pregnant Chinese women: a study protocol for a multicentre, prospective cohort trial
... Background: Neonatal alloimmune thrombocytopenia (NAIT), caused by maternal antibodies raised against alloantigens carried on foetal platelets, is a very common haematological abnormality in newborns ...
5
Molecular identification of T cells that respond in a primary bulk culture to a peptide derived from a platelet glycoprotein implicated in neonatal alloimmune thrombocytopenia
... Neonatal alloimmune thrombocytopenia induced by the human platelet alloantigen 1a (HPA1a) is characterized by generation of alloantibodies by a mother who is homozygous for the HPA1b alloantigen and almost ...
8
Incidence and Consequences of Neonatal Alloimmune Thrombocytopenia: A Systematic Review
... severe neonatal throm- bocytopenia due to NAIT and intracra- nial hemorrhage: PubMed, Embase, and ...Thrombocytopenia, Neonatal Alloim- mune ” [Majr] OR “ alloimmune throm- bocytopenia ” [ti] OR “ ...
9
Survey of platelet glycoprotein specific antibodies and HLA class 1 antibodies in a cross section of Nigerian multiparous women
... to neonatal alloimmune thrombocytopenia (NAIT), platelet refractoriness (PR) and post transfusion purpura (PTP) caused by platelet specific antibodies ...
5
Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: a laboratory study using an in vitro model
... and neonatal alloimmune thrombocytopenia (FNAIT) is a bleeding disorder caused by maternal antibodies against paternal human platelet antigens (HPAs) on fetal ...
8
Predictors of Neonatal mortality in Neonatal intensive care unit at referral Hospital in Southern Ethiopia: a retrospective cohort study
... that neonatal mortality is the out- come of complex relationship between neonatal, mater- nal and health care-related ...Ethiopia’s neonatal mortality dropped from 63 to 23 per 1000 live births with ...
9
Clincal Audit of Admission Pattern and its outcome in the NICU of Rehman Medical Institute, Peshawar
... A retrospective study conducted at the Neo- natal Intensive Care Unit (NICU), Department of Pediatrics, Rehman Medical Institute, Peshawar, Pakistan from June, 2006 to June, 2012. A total of 4900 neonates admitted to the ...
6
Perinatal Characteristics and Outcome of Neonates at NICU of a Tertiary Level Hospital in Bangladesh
... National Neonatal Perinatal Database which was recently launched in different institutes of the country including BSMMU will be a useful tool in analyzing newborn morbidity and mortality and also in the overall ...
6
Neonatal Morbidity and Mortality Trend in a Special Care baby Unit of a Tertiary Hospital in Yola: the Need to Educate Health Workers and Mothers on Quality Neonatal Health Practices
... Background: Neonatal morbidities like neonatal sepsis (NNS), prematurity and perinatal asphyxia constitutes the major causes of neonatal mortality worldwide, even though, there may be slight intra ...
5
Incidence, bacteriological profile and risk factor analysis of neonatal sepsis in a peri urban set up of North India
... helpful in guiding the priorities of health-programme and making policies to end preventable child deaths. In this study we report the incidence, risk factors, profile of pathogens causing neonatal sepsis and ...
6