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Neonatal mouse

A Neonatal Mouse Model of Coxsackievirus A16 for Vaccine Evaluation

A Neonatal Mouse Model of Coxsackievirus A16 for Vaccine Evaluation

... Both EV71 and CA16 have similar viral structures, because they belong to the same Enterovirus genus. Studies concerning the EV71 neonatal mouse model showed that EV71 was neurotropic and might enter the ...

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Multiple supporting cell subtypes are capable of spontaneous hair cell regeneration in the neonatal mouse cochlea

Multiple supporting cell subtypes are capable of spontaneous hair cell regeneration in the neonatal mouse cochlea

... 2014). Co-expression of β -galactosidase or tdTomato with HC markers after damage provided evidence that regenerated HCs were derived from the SC population. In addition, a small percentage of newly generated, ...

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Rotavirus Genome Segment 7 (NSP3) Is a Determinant of Extraintestinal Spread in the Neonatal Mouse

Rotavirus Genome Segment 7 (NSP3) Is a Determinant of Extraintestinal Spread in the Neonatal Mouse

... A neonatal mouse model of heterologous rotavirus infection was described, characterized, and used extensively to study rotavirus immunology and pathogenesis (25, ...the neonatal mouse as ...

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Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo

Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo

... the neonatal mouse cochlea is capable of spontaneous hair cell regeneration after damage in ...the neonatal cochlea might shed light on the competence of supporting cells to regenerate hair cells and ...

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Neuregulins are essential for spermatogonial proliferation and meiotic initiation in neonatal mouse testis

Neuregulins are essential for spermatogonial proliferation and meiotic initiation in neonatal mouse testis

... To determine the relationship between the NRGs/ERBB and the RA and FSH pathways, we first examined whether Nrg mRNA expression is activated by AM580 and FSH. Nrg1 and Nrg3 mRNA expression was stimulated by AM580 and FSH ...

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Selective Accumulation of Th2-skewing Immature Erythroid Cells in Developing Neonatal Mouse Spleen

Selective Accumulation of Th2-skewing Immature Erythroid Cells in Developing Neonatal Mouse Spleen

... Current thinking is that the immune system of the neonate is unique compared to that of adults and even older children, and that more sophisticated ap- proaches must be sought in order to achieve effective vaccination ...

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MicroRNAs and Their Targets Are Differentially Regulated in Adult and Neonatal Mouse CD8+ T Cells

MicroRNAs and Their Targets Are Differentially Regulated in Adult and Neonatal Mouse CD8+ T Cells

... Importantly, some miRNAs were expressed relatively uni- formly in the thymus, independent of age, whereas others varied by age (Figure 7B); this result indicated that changes in expres- sion of different miRNAs do not ...

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Large scale production of growing oocytes in vitro from neonatal mouse ovaries

Large scale production of growing oocytes in vitro from neonatal mouse ovaries

... from mouse neonatal ovaries is possible without the need for follicular cell ...in neonatal ovaries are usually very difficult to collect intact; their follicular structure is very ...

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GATA4 regulates Fgf16 to promote heart repair after injury

GATA4 regulates Fgf16 to promote heart repair after injury

... the neonatal stage, this endogenous regenerative capacity is lost with ...for neonatal cardiac ...for neonatal mouse heart regeneration. Using the neonatal mouse heart cryoinjury ...

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Study of Tnp1, Tekt1, and Plzf Genes Expression During an in vitro Three-Dimensional Neonatal Male Mice Testis Culture

Study of Tnp1, Tekt1, and Plzf Genes Expression During an in vitro Three-Dimensional Neonatal Male Mice Testis Culture

... tissue. Germ cell molecular changes are very valuable tools for improving spermatogenesis. The results obtained from this study revealed that the use of “α- MEM by KSR” can cause tissue survival and also can improve the ...

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Junctophilin-2 Protects Cardiomyocytes against Palmitate-induced Injury

Junctophilin-2 Protects Cardiomyocytes against Palmitate-induced Injury

... Figure 20: Inhibition of Ca 2+ release from RyR2 reduces JPH2 knockdown-induced CHOP protein expression in neonatal mouse cardiomyocytes.. 72.[r] ...

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Comparative virulence of human isolates of coagulase negative staphylococci tested in an infant mouse weight retardation model

Comparative virulence of human isolates of coagulase negative staphylococci tested in an infant mouse weight retardation model

... To further expand these studies with the neonatal mouse as the research model, reference and fresh clinical strains were identified to species level in the study reported here and were t[r] ...

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Ovariectomy enhances and estrogen replacement inhibits the activity of bone marrow factors that stimulate prostaglandin production in cultured mouse calvariae

Ovariectomy enhances and estrogen replacement inhibits the activity of bone marrow factors that stimulate prostaglandin production in cultured mouse calvariae

... cultured neonatal mouse calvariae of bone marrow supernatants (MSup) from sham-operated (SHAM), ovariectomized (OVX), or 17 beta-estradiol (OVX+E)-treated ...

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Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro.

Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro.

... In this article, we report i the attenuated phenotype of virus derived from TotollOl in the neonatal mouse system, ii the development of a Sindbis virus cDNA clone which produces virulen[r] ...

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Occurrence of multi-oocyte follicles in aquaporin 8-deficient mice

Occurrence of multi-oocyte follicles in aquaporin 8-deficient mice

... in neonatal mouse ovary, sug- gesting that altered granulosa cell or pre-granulosa cell function by AQP8 deletion is responsible for the forma- tion of ...of mouse granulosa cells, as AQP8 deletion ...

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Pemphigoid and pemphigus antigens in cultured epidermal cells

Pemphigoid and pemphigus antigens in cultured epidermal cells

... This study has shown, firstly, that the addition of pemphigoid and pemphigus IgG fractions alter the monolayer morphology of neonatal mouse epidermal cells grown in culture.. Untreated c[r] ...

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The hippo signaling pathway: implications for heart regeneration and disease

The hippo signaling pathway: implications for heart regeneration and disease

... to neonatal cells ...adult mouse heart, which causes increased Yap activation, also triggered increased cardio- myocyte proliferation [125], providing further evidence that Hippo signaling restrains adult ...

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The effects of melatonin on colonization of neonate spermatogonial mouse stem cells in a three-dimensional soft agar culture system

The effects of melatonin on colonization of neonate spermatogonial mouse stem cells in a three-dimensional soft agar culture system

... The present study makes noteworthy contributions by providing valuable tools for the in vitro investigation of SSC proliferation which can be useful in the treatment of male infertility. In the present study, we ...

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Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice

Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice

... the neonatal mouse brain was not significantly changed after HI compared with non-HI controls at 6 h, but it decreased at 24 h after HI (p = ...the mouse brain did not begin to increase until 24 h (p ...

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Neonatal influenza infection causes pathological changes in the mouse brain

Neonatal influenza infection causes pathological changes in the mouse brain

... Influenza A virus infections have been proposed to be associated with a broad spectrum of central nervous system complications that range from acute encephalitis/encephalopathy to neuropsychiatric disorders in humans. In ...

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