Neoplastic Cells
Neoplastic cells are a rare component in human glioblastoma microvasculature
... endothelial cells to label with p53 protein, and in double immunofluorescence/FISH experiments reported alterations in chromosomes 10, 19q, and 22q in neoplastic cells and a subset of endothelial ...
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Immunohistochemical characterization of neoplastic cells of breast origin
... and progesterone receptors (ER and PR), gross cystic disease fluid protein-15 (GCDFP-15), mammaglobin (MAG)-A and MAG-B [6-9]. Fritzsche et al. showed 73.3% and 72.1% cytoplasmic positivity for GCDFP-15 and MAG, ...
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Lateral inhibition of Notch signaling in neoplastic cells
... During normal development, several mechanisms are used to regulate Notch activity when groups of similar cells express both ligand and receptor, with the best studied of these being lateral inhibition. This ...
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The effect of erythropoietin on normal and neoplastic cells
... Abstract: Erythropoietin (Epo) is an essential hormone that binds and activates the Epo receptor (EpoR) resident on the surface of erythroid progenitor cells, thereby promoting erythropoiesis. Recombinant human ...
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Cytoskeletal mechanisms responsible for invasive migration of neoplastic cells
... suspended cells is covered with blebs or, more rarely, with ...these cells touch the substrate, they extend first filopodia and then lamellipodia in all directions, their central body becomes flattened so ...
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Posttranscriptional stabilization underlies p53 independent induction of p21WAF1/CIP1/SDI1 in differentiating human leukemic cells
... neoplastic cells from patients with various hematological malignancies as well as in normal bone marrow mononuclear cells and in myeloid and lymphoid cell lines independent of their p53 ...HL-60 ...
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Pathogenesis of follicular lymphoma
... the neoplastic cells are organized in follicles, express germinal center surface markers such as BCL6 and CD10, and have a characteristic gene expression profile of centrocytes and/or centroblasts (15, 18) ...
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Endosulfan Causes Neoplastic Changes in the Liver Cells of Mice
... and neoplastic growths in hepatocytes denotes neoplastic condition while degeneration in rough endoplasmic reticulum (RER) leads to cleavage of ribosomes from the RER making in free lying poly- ribosomes in ...
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Epithelioid and spindle-cell haemangioendothelioma in the brain of a dog: a case report T. Yaman*, A. Uyar, O.F. Keles, Z. Yener
... the neoplastic endothelial cells in this dog’s tumour exhibited a plump epithelioid or histiocytic appearance and a slightly differentiated spindled endothelial component, with a myxoid stroma similar to ...
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Increased CD70 expression is associated with clinical resistance to cisplatin-based chemotherapy and poor survival in advanced ovarian carcinomas
... on neoplastic cells of ovarian carcinoma and not on normal ovarian epithelial cells, making it an attractive target for antitumor drug development; however, the expression levels of CD70 in ovarian ...
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www.ijcep.com /ISSN: 1936-2625/IJCEP1205001 Case Report Intravascular large B-cell lymphoma with hemophagocytic syndrome (Asian variant) in a Caucasian Patient
... lymphoma cells are found exclusively within the lumen of small blood ves- sels and vascular spaces such as hepatic sinu- soid, and capillaries which makes recognition of the neoplastic cells in the ...
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Original Article Signet-ring cell in papilloma virus type 6 and 16-related non-neoplastic squamous cell lesion
... immature cells because neoplastic cells ex- press both squamous and adenocarcinoma hallmarks, including low molecular weight cyto- keratin, high molecular weight cytokeratin, MUC5AC and p63 ...
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Cerebral astrocytoma in a sheep
... Neoplastic cells typically have obvious astrocytic appearances histologically, although this can sometimes be difficult to distinguish from reactive astrocytosis, particularly in biopsy specimens taken from ...
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Case Report Mammary epithelioid myofibroblastoma mimicking invasive carcinoma: case report and literature review
... oid cells, which had variable pale to eosinophil- ic cytoplasm with stellate processes, and round to oval, central or eccentric nuclei with incon- spicuous or prominent basophilic ...epithelioid cells were ...
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An approach in the assessment of hematolymphoid neoplasms
... B cells undergo rearrangements of the T-cell receptor (TCR) and immuno-globulin (IG) genes, respectively, to generate diverse lymphoid populations with broad antigen detection ...of neoplastic cells ...
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Surgical Treatment of Hemangiopericytoma in the Lip of a Filly: A Clinical Report
... spindle-shaped cells surrounding the endothelial- lined vascular spaces. Neoplastic cells were arranged in short interlacing bundles and storiform whorls were randomly distributed throughout a ...
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Aldosterone-producing adrenocortical carcinoma with myxoid differentiation in a cat
... stroma. Neoplastic cells were moderate in size, polygonal, with moderate to abundant, occasionally granular, eosinophilic cytoplasm that contained a single round to oval nucleus, with finely clumped ...
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Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms
... and neoplastic cells, PNT1A and LNCaP cells were chosen to determine STEAP1 mRNA and protein stability through qPCR and western blot analysis, ...respectively. Cells were primarily cultured on ...
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FGF18 as a prognostic and therapeutic biomarker in ovarian cancer
... Conversely, neoplastic signaling could be conveyed by the presence of increased ligand (FGF18) without sig- nificant alteration in the expression level of the receptor ...
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The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms
... immortalized cells compared to a neuroblastoma cell line ...stem cells (MSC), rat cardiomyocytes (H9C2), a human hepatocyte cell line (MIHA) and human kidney cells (HK2), as well as the ...
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