Nephropathy and proteinuria
PREVALENCE OF PROTEINURIA AND NEPHROPATHY IN TYPE I DIABETES MELLITUS
... of proteinuria and further development of nephropathy among type 1 diabetic patients Sex: We noticed that there was slight male preponderance in the distribution of the ...
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Diabetic nephropathy is detected clinically by the presence of persistent microalbuminuria or proteinuria.
... Diabetic Nephropathy • Diabetic nephropathy is detected clinically by the presence of persistent microalbuminuria or ...of nephropathy is usually 15-25 years following onset of diabetes in type 1 but ...
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Spot urine protein/creatinine ratio as a reliable estimate of 24-hour proteinuria in patients with immunoglobulin A nephropathy, but not membranous nephropathy
... Background: Proteinuria is known to be associated with both kidney function deterioration and cardiovascular ...While proteinuria estimation from 24-h urine samples has traditionally been considered as the ...
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Addition of nonalbumin proteinuria to albuminuria improves prediction of type 2 diabetic nephropathy progression
... total proteinuria and albuminuria val- ues from each patient at baseline, we were able to estimate the amount of NAP through the following cal- culation: NAP-to-creatinine ratio (NAPCR) = protein- to-creatinine ...
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Retarding the Progression of Diabetic Nephropathy in Type 2 Diabetes Mellitus: Focus on Hypertension and Proteinuria
... of proteinuria has traditionally been viewed as a marker of renal injury, recent data suggest that proteinuria may actually be an independent modifiable risk factor for the progression of renal disease in ...
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Benazepril hydrochloride improves diabetic nephropathy and decreases proteinuria by decreasing ANGPTL-4 expression
... increased proteinuria in membranous nephropathy (MN) [8, ...decrease proteinuria in rats with MCD and DN [8, ...creases proteinuria in MCD rats, accompanied by a decrease of ANGPTL-4 ...
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‘Huang Qi Elixir’ for proteinuria in patients with diabetic nephropathy: a study protocol for a randomized controlled pilot trial
... Scr: Serum creatinine; TCM: Traditional chinese medicine; UAE: Urinary albumin excretion. Competing interests Xiang Tu and Sen Zhong are currently applying for patents concerning Flastem Milkvetch Seed and Huang Qi ...
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Divergent roles of Smad3 and PI3-kinase in murine adriamycin nephropathy indicate distinct mechanisms of proteinuria and fibrogenesis
... ADR nephropathy whereas others died from possible toxicity or even from exacerbation of the ...decreased proteinuria and fibrosis in ADR-treated mice, without affecting control ...
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Astragaloside IV attenuates proteinuria in streptozotocin-induced diabetic nephropathy via the inhibition of endoplasmic reticulum stress
... Diabetic nephropathy (DN) is a major cause of Chronic Kidney Disease and End-Stage Renal Disease throughout the world; however, the reversibility of diabetic nephropathy remains ...of proteinuria in ...
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Original Article Elevated baseline serum IgA may predict earlier proteinuria remission in IgA nephropathy patients
... of proteinuria in IgA nephropathy ...IgA nephropathy patients (proteinuria ...that proteinuria remission rate for patients with high serum IgA was 80%, 85%, 90%, 95% and 95% after 3, 6, ...
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High serum IgA/C3 ratio better predicts a diagnosis of IgA nephropathy among primary glomerular nephropathy patients with proteinuria ≤ 1 g/d: an observational cross-sectional study
... In China, there are many nephropathy patients with- out access to renal biopsy. This is for a variety of reasons – such as the uneven distribution of medical resources, the prevalence of rural hospitals without ...
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Original Article Calcitriol reduces proteinuria and improves bone mineral density in patients with diabetic nephropathy: a prospective randomized controlled study
... diabetic nephropathy (DN) is highly associated with proteinuria and bone mineral density ...on proteinuria and BMD in DN pa- ...with nephropathy due to type 2 diabetic mellitus (T2DM) to ...
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IP3R-Grp75-VDAC1-MCU calcium regulation axis antagonists protect podocytes from apoptosis and decrease proteinuria in an Adriamycin nephropathy rat model
... ADR-induced nephropathy model was used to assess whether inhibiting the transfer of Ca 2+ to mito- chondrial matrix can protect against ...decreased proteinuria accompanied by significantly improved ...
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Comparison of the effects of hydroxychloroquine and corticosteroid treatment on proteinuria in IgA nephropathy: a case-control study
... We used a case-control design and adhered to STROBE guidelines/methodology. We reviewed the medical records from an IgAN database at Peking University First Hospital. This database contained 1363 patients biopsied from ...
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Original Article Clinicopathological characteristics and renal outcomes in IgA nephropathy patients with nephrotic range proteinuria
... range proteinuria are ...range proteinuria (proteinuria ...subnephrotic proteinuria group, patients in nephrotic range pro- teinuria group had higher serum creatinine (SCr), higher ...
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Mesenchymal Stem Cells Ameliorate Podocyte Injury and Proteinuria in a Type 1 Diabetic Nephropathy Rat Model
... Podocytes play a major role in maintaining the integrity and permeability of the glomerular filtration barrier [43,44]. In DN, the effacement of podocyte foot processes and the loss of slit diaphragm proteins result in a ...
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Angiotensin receptor blockers for the reduction of proteinuria in diabetic patients with overt nephropathy: results from the AMADEO study
... Bichu et al and the downstream production of the extracellular matrix protein fi bronectin and have been shown to improve insulin sensitivity, reduce triglyceride levels and decrease the risk for atherosclerosis. This has ...
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The difference between patients with nephrotic syndrome and nephrotic range proteinuria in IgA nephropathy: a propensity score matched cohort study
... Currently, there are limited clinical studies focused on the association between serum albumin and the progres- sion of kidney disease in IgAN patients with massive pro- teinuria. We compared the data of patients with NS ...
Urinary kidney injury molecule-1 is related to pathologic involvement in IgA nephropathy with normotension, normal renal function and mild proteinuria
... Fifty-one patients, aged >14 years, with renal-biopsy- proven IgAN, from Tianjin Medical University General Hospital between October 2011 and November 2013 were enrolled. Normotension was defined as systolic blood ...
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Effect of Ramipril Treatment on Proteinuria and Advanced Glycation End Products in Type 2 Diabetes Mellitus Patients with Nephropathy: One Year Follow up Study
... Micro-albuminuria is an indicator of diabetic nephropathy particularly at the early stage when significant change in serum creatinine level is not observed. In the present study we evaluated urinary ACR, serum ...
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