nerve growth factor receptor
NGF Induces Proliferation and Aggressiveness in Prostate Cancer Cells.
... androgen receptor and nerve growth factor receptor in prostate cancer cells: implications for a new. 725[r] ...
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Trk Family Neurotrophin Receptors and p75 Receptor A Multiple Competing Hypothesis Case in the Nerve Growth Factor (NGF) History
... the nerve growth factor receptor ...p75 receptor, resulted in that the consistency of the group take patterns of compe- ...p75 receptor functions are described as “enigmatic”, ...
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Dependence receptor UNC5D mediates nerve growth factor depletion–induced neuroblastoma regression
... the nerve growth factor (NGF) receptors TRKA and p75 NTR and are dependent on NGF for survival; however, the underlying molecular mechanism remains ...dependence receptor that is directly ...
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Multiple domain 'nexus' proteins in receptor-mediated cell signaling
... the nerve growth factor (NGF) receptor tyrosine kinase TrkA, activated H-Ras, B-Raf, and MEK2 and facilitates their coordinated signaling to prolonged ERK ...growth factor. These ...
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<p>Role of Nerve Growth Factor in Orofacial Pain</p>
... unresolved. Nerve growth factor (NGF) is a member of a family of neurotrophins and regulates the growth, maintenance and develop- ment of ...
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Effects of Nerve Growth Factor shRNA Inhibition on Asthma Phenotypes in a Mouse Model of Asthma
... study, nerve growth factor shRNA alleviated airway hyper-responsiveness by preventing muscarinic acetylcholine receptor M3 overexpression and smooth muscle cell hyperplasia in a mouse asthma ...
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Anti-nerve growth factor in pain management: current evidence
... of nerve growth factor (NGF) and its interaction with tropomyosin receptor kinase A (trkA) have been well character- ized as important mediators of pain initiation and maintenance, and ...
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Role of nerve growth factor and its TRKA receptor in normal ovarian and epithelial ovarian cancer angiogenesis
... TRKA receptor expression in normal OSE ...such receptor in that epithelium could not be ...TRKA receptor (p-TRKA), proving that such receptor is chiefly activated as tissue differentiation is ...
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Identification and characterization of the Cucurbitacins, a novel class of small molecule inhibitors of Tropomyosin receptor kinase a
... transmembrane receptor tyro- sine kinase for the neurotrophin, nerve growth factor (NGF), plays an important role in the pathogenesis of psoriasis and associated pruritus [23, ...
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Nerve growth factor and receptor expression in rheumatoid arthritis and spondyloarthritis
... known human neurotrophins and their four corresponding receptors in the synovial compartment of arthritis patients. The presence of neurotrophic factors in the inflamed joint has been described earlier [2,3]. Focusing on ...
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Characterisation of ERK distribution and activity in rat pheochromocytoma cells : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Biology at Massey University
... Nerve growth factor NGF binds to the NGF receptor, TrkA, at the tips of nerve cell axons, sending a signal that prevents programmed cell death and causes survival, growth, and differenti[r] ...
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Topical administration of adrenergic receptor pharmaceutics and nerve growth factor
... -adrenergic receptor antago- nists in the retina suggests that they do not prevent diabetic retinopathy in ...-adrenergic receptor blockade mediated by receptor signal- ing in the retina are not ...
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Mechanism and therapeutic effectiveness of nerve growth factor in osteoarthritis pain
... its receptors is an issue of debate. Recently, the development of surface plasmon resonance technology has enabled evalu- ation of the inhibitory potential of ALE-0540, PD90780, Ro 08-2750, and PQC083. These compounds ...
6
Role of lapatinib in the first-line treatment of patients with metastatic breast cancer
... Abstract: Lapatinib is a dual tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR/ErbB1) and human epidermal growth factor receptor 2 (HER2/ErbB2). EGFR and HER2 ...
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Selective use of vandetanib in the treatment of thyroid cancer
... Rat sarcoma (RAS) genes encode proteins activating MAPK and PI3K pathways (Figure 1). RAS activation depends on epidermal growth factor receptor (EGFR), and is often overexpressed if mutated. RAS ...
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Skin Targeting Approaches in Cosmetics
... Neverthless, some agents that stimulate collagen pro- duction can also be served as targets for enhancing collagen production in the skin. In the past, topical application of soluble animal collagen was used in an ...
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Triple-negative breast cancer: new perspectives for targeted therapies
... Abstract: Breast cancer is a heterogeneous disease, encompassing a large number of entities showing different morphological features and having clinical behaviors. It has became apparent that this diversity may be ...
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Challenging issues in molecular-targeted therapy
... drug also needs to modulate the expression of multiple genes that contribute in tumor development and angiogenesis, and it is required to induce other inhibition of VEGF signaling and angiogenesis as it is depicted in ...
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Muscle growth and flesh quality of farmed Atlantic halibut (Hippoglossus hippoglossus) in relation to season of harvest
... of growth (Rowlerson et ...1998). Growth of the fast muscle involves the hypertrophy of the embryonic fibres until around 150 degree days (10 mm LS) after which additional myotubes are formed (Galloway et ...
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Regulation of the synthesis of nerve growth factor
... Regulation of NGF synthesis in peripheral target organs after nerve transections: the iris as a model svstem In a first approach to test whether the state of innervation Ebendal, Olson &[r] ...
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