Neural Progenitor Cells
Direct conversion of mouse astrocytes into neural progenitor cells and specific lineages of neurons
... atic cells into induced neural progenitor cells ...stem cells (iPSCs), more primitive stem cells than NPCs [4, ...somatic cells into self-renewable and lineage-restricted ...
15
Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells
... stem cells as well as ...or neural progenitor cells to further challenge through the involve- ment of the NLRP3 inflammasome pathway that acts as a sensor of cell metabolism and that finally ...
15
Borna Disease Virus Infects Human Neural Progenitor Cells and Impairs Neurogenesis
... tion, cells were analyzed at each passage for survival, at passages 2, 3, 4, 6, and 10 for infection, protein level, and morphology, and at passages 3 and 8 for ...the cells were infected as determined by ...
11
Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells
... of neural/glial progenitor cells [17] [20] [21] ...in neural progenitor cells upon PDGFB ...glial cells in the brain and tumor initiation ...of neural and glioma ...
9
Forcing neural progenitor cells to cycle is insufficient to alter cell-fate decision and timing of neuronal differentiation in the spinal cord
... of cells retaining neural progenitor characteristics found in the mantle layer have also been described ...proliferating cells are present in the mantle layer in the hindbrain of jmj mutant ...
16
Genetic screening and multipotency in rhesus monkey haploid neural progenitor cells
... stem cells (haESCs) have been extensively applied in forward and reverse genetic ...haploid cells are restricted to ...haploid neural progenitor cells (haNPCs), which maintained ...
9
ADAM23 promotes neuronal differentiation of human neural progenitor cells
... To elucidate possible mechanisms for ADAM23 effects on cell survival and neuronal differ- entiation, RNA microarray analysis was performed in triplicate on ADAM23 overexpressing and underexpressing cells 3 days ...
13
Lin28 promotes the proliferative capacity of neural progenitor cells in brain development
... Fig. 7. Igf1r and Hmga2 are functionally important targets of Lin28a/b. (A) Western blot analysis of Igf1r and Hmga2 expression using lysates from NPCs of wild-type and Lin28a − / − b +/ − compound mutant cerebral ...
12
Cellular therapy after spinal cord injury using neural progenitor cells
... pressing cells (Molecular Probes, Leiden, The Netherlands; at 1/1000) mouse- anti-A2B5 for glial committed progeni- tors (Chemicon, Hofheim, Germany; at 1/100), mouse-anti-GFAP for astroglia (Chemicon, Hofheim, ...
186
Challenges of Using MR Spectroscopy to Detect Neural Progenitor Cells In Vivo
... Future attempts to detect and measure NPCs should exploit alternative methods of signal processing that incorporate all known prior knowledge of the MR spectroscopy signals present in th[r] ...
6
CCL11 promotes migration and proliferation of mouse neural progenitor cells
... Fig. 3 Isolation of NPCs and migration assay. a The neurosphere from embryonic and infant mouse brains. Genes involved in proliferation and multipotency were expressed in cultured NPCs. Scale bar = 50 μ m. b ...
11
The potential of neural progenitor cells: an investigation into their fate in vitro and after transplantation
... Following from the observations that hippocampal progenitors cells produce neurons in vivo and that stem cells isolated from the ventricular zone can undergo in vitro neurogenesis Reynol[r] ...
158
Endocytic Regulation of Notch Signaling in Drosophila Melanogaster Neural Progenitor Cells
... Notch is a highly conserved signaling pathway that is used in many different contexts during development. In Drosophila, Notch plays a part in the development of almost all cell types, where its key role is to specify or ...
143
Exosomes released from neural progenitor cells and induced neural progenitor cells regulate neurogenesis through miR-21a
... + cells reduced significantly while that of GFAP + cells significantly increased when miR-21a expression was inhibited ...+ cells increased significantly while that of GFAP + cells decreased ...
10
Coxsackievirus Preferentially Replicates and Induces Cytopathic Effects in Undifferentiated Neural Progenitor Cells
... and cells were harvested after a period of time (days 3 and 14 ...comparison, cells from 5-day-differentiated cul- tures were infected with eGFP-CVB3 at a low MOI (MOI of ...Diff.] cells) were ...
15
Human neural progenitor cells retain viability, phenotype, proliferation, and lineage differentiation when labeled with a novel iron oxide nanoparticle, Molday ION Rhodamine B
... neuroprogenitor cells were effectively labeled with MIrB in ...neuroprogenitor cells were incubated with MIrB (20 µg Fe/mL) for 2 days (A, ...outgrowth cells contained MIrB ...outgrowth cells ...
8
Manifestation of Huntington’s disease pathology in human induced pluripotent stem cell-derived neurons
... stem cells (PSCs), have jointly engendered new disease models based on induced PSCs (iPSCs) derived from the som- atic cells of patients with particular afflictions [9, ...of neural progenitor ...
15
Post-CNS-inflammation expression of CXCL12 promotes the endogenous myelin/neuronal repair capacity following spontaneous recovery from multiple sclerosis-like disease
... that neural progenitor cells may in fact express both the CXCR4 receptor and its CXCL12 ...these neural cells may occur via auto- crine signaling mechanism [40, ...whether neural ...
19
Context-dependent functions of specific microRNAs in neuronal development
... cell-derived neural progenitor cells miR-9 is upregulated during in vitro neural differentia- tion of mouse ESCs [58] and adult neural stem/pro- genitor cells [59], and during ...
9
Molecular and cellular events underlying the response of CNS neurons to structural injury
... Specifically, adaptive injury-induced alterations included the activation of various cell populations, particularly neural progenitor cells, astrocytes and microglia, which may contribut[r] ...
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