Neuromuscular transmission
Transcription Factors in Muscle Atrophy Caused by Blocked Neuromuscular Transmission and Muscle Unloading In Rats
... The muscle wasting associated with long-term intensive care unit (ICU) treatment has a negative effect on muscle function re- sulting in prolonged periods of rehabilitation and a decreased quality of life. To identify ...
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Graded neuromuscular transmission in the heart of the isopod crustacean Ligia exotica
... synaptic transmission has been demonstrated in many nonspiking and spiking neurones in central and peripheral ganglia (for a review, see Pearson, ...excitatory neuromuscular junctions of both vertebrates ...
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Evidence for cholinergic inhibitory and serotonergic excitatory neuromuscular transmission in the heart of the bivalve Mercenaria mercenaria
... gastropod and cephalopod species, we have shown that neural cardiac excitation and inhibition are mediated by discrete EJPs and IJPs and that, in the gastropod heart, IJPs are ACh- mediated Cl − currents antagonized by ...
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Calpain activation impairs neuromuscular transmission in a mouse model of the slow channel myasthenic syndrome
... substrate was increased at the NMJ of dissociated muscle fibers. Inhibition of calpain using a calpastatin (CS) transgene improved strength and neuromuscular transmission. CS caused a 2-fold increase in the ...
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Neuromuscular Transmission in a Sea Anemone
... Neuromuscular transmission in a sea anemone Potentials could be recorded with an external suction electrode only from the upper margin of the column overlying the sphincter, the tentacle[r] ...
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The effects of myomodulin and structurally related neuropeptides on skeletal neuromuscular transmission in the locust
... Mytilus catch-relaxing peptide (CARP), which is a structurally related homologue of myomodulin A with two amino acid substitutions in its N-terminal region (Hirata et al. 1987), is only slightly less potent than ...
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Glutamatergic neuromuscular transmission in the heart of the isopod crustacean Ligia exotica
... Neuromuscular transmission between the CG and myocardium has been investigated in several ...the neuromuscular junction between the CG and myocardium in the heart of ...
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Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3
... For the first time, positive NCX3-ir was detected at the NMJ and in nerve ramifications between muscle fibers. Although a clear demonstration of the presence of NCX3 protein at the presynaptic level is currently lack- ...
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Effect of zidovudine and its interaction with rocuronium on neuromuscular transmission
... Neuromuscular weakness is often found in patients receiving zidovudine therapy due to mitochondrial damage. Effect of zidovudine was evaluated in indirectly and directly stimulated isolated rat phrenic nerve ...
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Neuromuscular transmission in Peripatus
... Spikes in DL muscle, i During reflex activation, ii, iii In response to single strong shock applied to a small piece of nerve cord nearby.. Lower traces are isometric force records..[r] ...
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Neurohormonal modulation of the Limulus heart: amine actions on neuromuscular transmission and cardiac muscle
... Amine modulation of heartbeat rate and duration are primarily due to effects upon cardiac ganglion pacemaker and follower neurones, while enhancement of heartbeat amplitude is due to eff[r] ...
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Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis
... Amyotrophic lateral sclerosis (ALS) is a debilitating and fatal neurodegenerative disorder affecting motor function, with mean survival of 3 years from disease onset. Considerable progress has been made in unrav- eling ...
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Temperature Effects on Neuromuscular Transmission (Opener Muscle of Crayfish, Astacus Leptodactylus)
... 13, the tension reached during a train of e.p.s.p.s is proportional to the product of suprathreshold depolarization and coupling factor: although the latter has a positive Qlo, the mean [r] ...
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Effect of lanthanum ions on neuromuscular transmission in insects
... Spontaneous release of transmitter The experiments on spontaneous release of transmitter were performed on the cockroach muscle in order to compare with the effect of cobalt at the cockr[r] ...
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Potentiation of Neuromuscular Transmission by an Octopaminergic Neurone in the Locust
... A The effect of spikes in DUMETi on the basal tonus of the extensor tibiae muscle and on the amplitude of twitch tension generated by stimulating the slow extensor tibiae motoneurone SET[r] ...
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Neuromuscular Transmission in the Longitudinal Layer of Somatic Muscle in the Earthworm
... vii The M.I.J.P.'S and I.J.P.'S elicited by stimulation of the inhibitory nerve reversed their polarities in a chloride-deficient solution.. viii Reversal potential for the I.J.P.[r] ...
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Allatostatin decreases stomatogastric neuromuscular transmission in the crab Cancer borealis
... invertebrate neuromuscular junctions, the amplitude of the muscle contractions produced by a given temporal pattern of motor neuron discharge can be influenced by neuromodulatory substances, which are either ...
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Neuromuscular transmission in the jellyfish Aglantha digitale
... This result could be accounted for if synapses between the lateral motor neurones and the myoepithelium were confined to the region up to 800 ^m from the motor giant axon and the respons[r] ...
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Loss of MUNC13-1 function causes microcephaly, cortical hyperexcitability, and fatal myasthenia
... In vitro analysis of neuromuscular transmission. The fre- quency of the spontaneous MEPPs was reduced to 2% of normal (table 1). Depolarization of the nerve terminals by increasing the external K 1 ...
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Myasthenia gravis: past, present, and future
... of neuromuscular transmission, which results from the binding of autoantibodies to proteins involved in signaling at the neuromuscular junction ...cause neuromuscular transmission ...
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