Neuron apoptosis
Protective effect of dexmedetomidine on the propofol-induced cognitive dysfunction and neuron apoptosis in rats
... excessive apoptosis of neurons is considered to be an important pathological link for the propofol to cause cognitive dysfunction [3] , but it is still unclear about the specific prevention and treatment methods ...
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Original Article The protective effect of the Rho-kinase inhibitor hydroxyfasudil on propofol-induced hippocampal neuron apoptosis in neonatal rats
... promote neuron growth and alleviate nerve ...the apoptosis of primary retinal gan- glion cells and relieves retinal nerve injury ...hippocampal neuron apoptosis induced by ...propofol-induced ...
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Original Article Dynamic change of SGK expression and its role in neuron apoptosis after traumatic brain injury
... on neuron death processes. Among apoptosis pathway, caspase-3 is a key ...and neuron apopto- sis, as shown in Figure ...in neuron apoptosis (Figure ...
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Segment specific prevention of pioneer neuron apoptosis by cell autonomous, postmitotic Hox gene activity
... Hox genes have been shown to activate apoptosis in post- embryonic neuroblasts and maxillary cells (Bello et al., 2003; Lohmann et al., 2002). However, the specific expression of Abd-B in posterior dMP2 neurons ...
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Nrdp1 increases neuron apoptosis via downregulation of Bruce following intracerebral haemorrhage
... Related evidence demonstrated that the degradation of the gigantic (530 kDa) inhibitor-of-apoptosis protein BRUCE/apollon is a crucial point in apoptosis. BRUCE has also been identified to be degraded in ...
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Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS
... underlined. The asterisks indicate the ALS-related mutations that occur in patients. Additional file 1: Figure S2 Large magnification of the motor neuronal cells indicating the localization of the proteins expressed in ...
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Original Article 2-BFI inhibits hippocampal neuron apoptosis and NMDA receptor expression in chronic epileptic rats
... Epilepsy is one of the most common central nervous system (CNS) diseases, secondary only to stroke [1]. It has been shown that the imbalance in inhibitory and/or excitatory neu- rotransmitters (such as γ-aminobutyric ...
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Original Article Down-regulation of GAP-43 by inhibition of caspases-3 in a rat model of neuropathic pain
... the neuron sprouting, the GAP-43 is massively synthesized accompanied by the growth of axons and has been applied as a marker of axon growth ...between neuron apoptosis and ...caspase-3 ...
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Hyperbaric Oxygen Pretreatment Improves Cognition and Reduces Hippocampal Damage Via p38 Mitogen Activated Protein Kinase in a Rat Model
... In summary, HBO pretreatment greatly improved the learn- ing and memory ability by inhibiting dendritic spine loss and reduced the neuron apoptosis, astrocyte activation, and TNF-α production in the ...
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<p>Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway</p>
... The incidence of ischemic stroke has continued to increase in recent years. 29 Cognitive impairment caused by learning and memory impairment is one of the most common complications of stroke. 30 The restoration of blood ...
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TNFRSF17 led to just the opposite phenomenon. Notably, the regulation effects of TNFRSF17 on apoptotic related genes and proteins under hypoxia
... cell apoptosis by the T-cell dependent activation of memory B cells ...[29]. Neuron apoptosis, which is the main cause of death, plays a key role in the pathological process of HIBD because it can ...
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Original Article Upregulation of miR-137 protects anesthesia-induced hippocampal neurodegeneration
... CA1 neuron apoptosis was significantly reduced, and mem- ory loss markedly rescued by miR-137 upregu- lation (Figure 2B-F), suggesting that miR-137, through its upregulation, played critical role in ...
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Intermittent hypoxia from obstructive sleep apnea may cause neuronal impairment and dysfunction in central nervous system: the potential roles played by microglia
... IH-induced neuron apop- tosis and CNS dysfunction could in fact be orchestrated largely by microglia-mediated oxidative stress and inflam- matory impairments at the cellular ...IH-induced neuron ...
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Single prolonged stress induces apoptosis in dorsal raphe nucleus in the rat model of posttraumatic stress disorder
... in apoptosis by transduction or magnification of apoptotic ...in apoptosis induced by the mitochondrial pathway ...of apoptosis in dorsal raphe nucleus in the rat model of ...
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Original Article MicroRNA-137 inhibits apoptosis of neuron cells in injured spinal cord by targeting calpain 2
... undergo apoptosis, resulting in progressive degenera- tion, loss of the tissue in the spinal cord and permanent neurological disability [9, ...neuronal apoptosis may be a therapeutic strat- egy of SCI ...
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Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors
... In some cancer cell contexts, effects of Gmnn inhibition have been shown to be independent of the mutational status of the tumor suppressor TP53, with Gmnn loss inducing accumulation of excess genomic DNA, G2/M ...
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Timing control of single neuron spikes with optogenetic stimulation
... Results in [12], [13] demonstrate that the Izhikevich model can produce the behaviors of different types of cortical neu- rons by appropriately tuning the parameters {a, b, c, d}, even though the model itself is not ...
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Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury
... that neuron-to-neuron α-syn passage involves active mecha- nisms between relatively healthy cells and is therefore most efficient when neuronal integrity is ...
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Axonal Transport Enables Neuron-to-Neuron Propagation of Human Coronavirus OC43
... autonomic circuitry. Indeed, the trigeminal nerve possesses nociceptive neurons, which are present in the respiratory epithelium of the nasal cavity (65) and can theoretically be infected by HCoV OC43 to invade the CNS, ...
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Mod 4 PPT.ppt
... • Dendrite – The branching extensions of a neuron that receive information and conduct impulses toward the cell body (soma).... Parts of the Neuron - Soma.[r] ...
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