neuropeptide Y (NPY)
Hypothalamus-adipose tissue crosstalk: neuropeptide Y and the regulation of energy metabolism
... of NPY treatment on lipid accumulation in 3 T3-L1 cells at 8 days post-differentiation ...of NPY on adi- pose tissue function were thought to occur mainly via NPYR1- and NPYR2-mediated pathways, although ...
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The effect of hydro-alcoholic extract of ephedra pachyclada on serum concentrations of neuropeptide Y and ghrelin hormones and body weight in male rats
... Neuropeptide Y (NPY) is considered as the most abundant peptide hypothalamus and its most important effect is stimulating food ...words, NPY gene is the candidate gene for obesity; it is the ...
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Neuropeptide Y functions as a facilitator of GDNF induced budding of the Wolffian duct
... as neuropeptide Y ...matching, NPY was also found to correlate most significantly to the budded condition with a high degree of connectedness to genes with developmental ...Exogenous NPY [as ...
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Adrenalectomy reduces neuropeptide Y–induced insulin release and NPY receptor expression in the rat ventromedial hypothalamus
... Obesity, which is an important risk factor for serious chronic illnesses such as insulin resistance, type 2 dia- betes, and heart disease is caused by an imbalance between energy intake and energy expenditure. There are ...
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Original Article Biological effects of electrical stimulation on pelvic floor muscle strength and neuropeptide Y expression
... evaluate neuropeptide Y (NPY) expression and pelvic floor muscle strength of stress urinary incontinence (SUI) and diabetes rats before and after ES (electrical stimulation), and to compare the ...
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Effects of opioid antagonists naloxone and naltrexone on neuropeptide Y induced feeding and brown fat thermogenesis in the rat Neural site of action
... specific neuropeptide Y antagonists are not yet available, previous studies had shown that the opioid antagonist naloxone blocked neuropeptide Y- induced feeding when both drugs were injected ...
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Characterizing the Role of the Neuropeptide Y-Y5R System in Breast Cancer
... bi-directionally. NPY secretion has been found to be increased in transgenic mice that over-express tumour necrosis factor (TNFα) and inhibited in human astrocytes by interleukin ...29,30 NPY plays a ...
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Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells
... and NPY in an independent hema- topoietic trafficking model, we used the CXCR4 antagonist ...intact, NPY enhanced mobilization by AMD3100 and was associated with decreased EC VE-cadherin expression suggests ...
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Synergistic action of neuropeptide Y and adrenaline in the eel atrium
... Fig. 4. Time courses of the effects of eel NPY (eNPY) and adrenaline. Changes in the contractile force (A) and the beating rate (B) were plotted against time after the addition of 10 −7 mol l −1 eNPY ( d ), 3 × 10 ...
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Levels of neuropeptide Y in synovial fluid relate to pain in patients with knee osteoarthritis
... of NPY in infection and inflammation, as well as in auto- immunity, has been suggested ...of NPY in the dorsal root ganglia and spinal cord has been shown in various models of inflammatory and neuropathic ...
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The Impact of the Neuropeptide Y System on the Progression of Breast Cancer
... The immune system influences microenvironmental interactions between tumor cells and the host–tissue; such interactions mediate primary tumor development and play an important role in the metastatic cascade. Thus, in ...
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Neuropeptide Y inhibits interleukin-1β-induced phagocytosis by microglial cells
... major by a monocyte/macrophage murine cell line [43]. Since infection of phagocytes is a crucial step for repli- cation of Leishmania major, inhibiting phagocytosis results in a protective action [44]. Moreover, the ...
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Ethanol-induced locomotor sensitization and ethanol consumption : the role of neuropeptide Y
... 1992). NPY is widely expressed throughout the central nervous system (Gray & Morley, 1986) and modulates a wide-range of neurobiological functions (Heilig & Widerlov, ...for NPY in the regulation of ...
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Production, characterization, and expression of neuropeptide Y by human pheochromocytoma
... tissue NPY levels simultaneously as well as to study its release and expression in patients with either adrenal or extraadrenal ...Plasma NPY levels were higher (P < ...
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Neuropeptide y binding sites in rat brain and their relevance to the possible anxiolytic-like activity of receptor ligands
... cannula (Figure 2.1). The internal cannula was attached to a 50|il H am ilton syringe via a 40cm length of connecting tubing (Plastics One Inc.). The syringe and connecting tube were filled w ith saline and a small air ...
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Synthesis, Characterization and Biological activity of Novel 6 Methyl 2 oxo N (4 (Piperidin 1 yl) Phenyl) 1,2,3,4 Tetrahydropyrimidine 5 Carboxamide Derivatives
... and neuropeptide Y (NPY) antagonists, explains the widespread presence of studies related to the “Biginelli compounds in the specialized literature,[5] not to mention the fact that several marine ...
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Reproduction and beyond, kisspeptin in ruminants
... ARC neuropeptide Y (NPY) gene expression and a decrease in proopiomelanocortin gene expression ...in NPY-GFP transgenic mice found that Kiss1r mRNA was produced in NPY neurons ...
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Toxic_Stress_and_Obesity_AG.pdf
... activity. Neuropeptide Y (NPY), a neuropeptide released centrally when the stress system is activated, will be addressed, as it interacts with both the HPA axis, GCs, and these peripheral ...
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Neuromodulation of metabolic functions: from pharmaceuticals to bioelectronics to biocircuits
... ACh: Acetylcholine; AgRP/NPY: Agouti-related peptide/neuropeptide Y; ANS: Autonomic nervous system; AP: Artificial pancreas; ARC: Arcuate nucleus; BAT: Brown adipose tissue; CGM: Continu[r] ...
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Peripheral sympathetic mechanisms in orofacial pain
... Abbreviations: CGRP, calcitonin gene-related peptide; Ne, norepinephrine; NGF, nerve growth factor; NPY, neuropeptide Y; SCG, superior cervical sympathetic ganglion; SNS, sympathetic n[r] ...
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